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Late Deprescribing of Angiotensin-Converting-Enzyme Inhibitors and Renin-Angiotensin Blockers in Patients with Advanced Cancer Receiving Palliative Care

Background: Treatment with antihypertensives in patients with advanced cancer is often continued until very late in the disease trajectory, despite a considerable risk of hypotension. Objectives: The aim of this study was to investigate the time of deprescribing of antihypertensive agents in patients with cancer receiving palliative care during their last year of life. The monitoring of blood pres

Measuring the effects of pitch accent realization and the patterning of head and eyebrow gestures on perceived multimodal prominence

Co-speech head and eyebrow gestures often align with pitch accents in spoken language production, thereby likely instantiating what we could refer to as multimodal prominence. Indeed, when speech is perceived audio-visually, controlled experimental studies have shown that both pitch accents and head and eyebrow gestures, when independently manipulated, have sizable effects on perceived prominence.

Decompression at 1.3 versus 1.6 bar and Nitrogen Elimination and Venous Gas Emboli : A Randomized Controlled Trial

INTRODUCTION: The optimal depth for decompression stops is unclear. We hypothesize that a decompression stop at 1.3 bar, compared with 1.6 bar, decreases post-dive whole-body nitrogen washout volumes and venous gas emboli (VGE).METHODS: In this randomized crossover trial, divers performed wet air dives of 40 minutes at 3.4 bar (340 kPa) with a seven-minute-long decompression stop at either 1.3 bar

Methanol for marine propulsion

This chapter reviews methanol's properties as a fuel for marine use in general terms and then specifically for combustion engines and fuel cells. It discusses the different engine technologies being either investigated or demonstrated that allow methanol to be used in marine engines. Their potential in terms of power density, emissions, and efficiency, as well as their maturity are reviewed. The e

Experimental Philosophy, Ethnomethodology, and Intentional Action : A Textual Analysis of the Knobe Effect

In "Intentional action and side-effects in ordinary language” (2003), Joshua Knobe reported an asymmetry in test subjects’ responses to a question about intentionality: subjects are more likely to judge that a side effect of an agent’s intended action is intentional if they think the side effect is morally bad than if they think it is morally good. This result has been taken to suggest that the co

Autonomous navigation with convergence guarantees in complex dynamic environments

This article addresses the obstacle avoidance problem for setpoint stabilization tasks in complex dynamic 2-D environments that go beyond conventional scenes with isolated convex obstacles. A combined motion planner and controller is proposed that integrates the favorable convergence characteristics of closed-form motion planning techniques with the intuitive representation of system constraints t

Parameter Identification For Inter Turn Fault Detection In Permanent-Magnet Synchronous Motors Using Stator Flux Linkage DC Offset Monitoring

The parameters of PMSM with inter-turn fault are identified using a time-stepping finite element method (FEM). Analytical expressions (AE) uses the estimated parameters for fault analysis similar to FEM analysis. The fault waveforms, terminal voltages, obtained from the AE models are used for inter turn fault (ITF) detection, using Stator Flux Linkage DC offset (SFDO). A comparison is made between

Nanoconfined circular DNA

Studies of nanoconfined circular DNA are of interest both from a biological as well as a fundamental polymer physics perspective. We here present the use of nanofluidic channels as a tool for comparing statics and dynamics of the linear and circular configuration of the same DNA molecule.

Why can't I sit with my friend ? The complexity in diverse anti-discriminatory practices in school.

The UN Convention on the Rights of the Child state that in all actions concerning children the best interests of the child shall be a primary consideration. Children are capable of forming their own views and have the right to express those views freely. The school plays an important role in empowering children in this socialization process and Swedish schools have in its educational assignment a