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Genome-wide nonparametric linkage analysis of 480 sib-pairs affected with type 2 diabetes revealed linkage to a previously unreported susceptibility locus on chromosome 18p11. This result improved with stringent subphenotyping using age- and sex-adjusted BMI, ultimately reaching a logarithm of odds of 3.82 (allele sharing 0.6654) at a point between markers D18S976 and D18S391 when the most obese 2

Members of the parasitic dinoflagellate genus Amoebophrya lethally infect other marine dinoflagellates, including red tide forming and toxin-producing species. The known geographical distribution of Amoebophrya sp. parasites in costal waters of the northern hemisphere is more likely reflecting a lack of information from other areas rather than the actual picture. We investigated the presence of Am

The big Malmö newpapers Sydsvenska Dagbladet and Kvällsposten, both owned by the family Wahlgren, involved themselves heavily in Swedish party politics in the 1960s. The Social Democrats had in 1962 been in almost permanent power in Sweden since 1932. There was a desperate wish for change in power among many Swedishy voters. In this atmosphere Olof Wahlgren, Sydsvenska Dagbladet´s deputy editor,

BACKGROUND: To clarify the possible role of CagA positive (CagA+) Helicobacter pylori strains in the development of atrophic gastritis, the prevalence of antibodies to H. pylori and CagA (120 kD protein) was studied among subjects with atrophic and non-atrophic gastritis. METHODS: The study population was randomly selected among 12,252 Finnish men who were screened for atrophic corpus gastritis wi

We consider the stationary loss rate l(K) of a GI/G/1 queue with finite buffer of size K. Let X-n = U-n - T-n, n >= 1 where U-n is the service time, T-n is the interarrival time and let rho be the traffic intensity. We derive sharp asymptotics for the loss rate as K -> infinity, in the cases (i): rho > 1, and (ii): rho < 1 and X-n non-lattice with light tails. We also look at another reflection, r

The cyclicity of Arctic populations of small rodents is a subject with a long history and a large literature (Batzli, 1992) in which the question "What drives the cycle?" has received many answers, among them that the source of the cycle is either rodent interaction with food or the interaction with predators or both. Another question concerns the confinement of the cycle to Arctic conditions. The

The dynamical random graphs associated with a certain class of biological neural networks are introduced and studied. We describe the phase diagram revealing the parameters of a single neuron and of the synaptic strengths which allow formation of the stable strongly connected large groups of neurons. It is shown that the cycles are the most stable structures when the Hebb rule is implemented into

We have observed a feature at similar to2.5 eV binding energy (BE) in the valence band of La1-xSrxMnO3 single crystals not previously reported in the literature. The relative intensity of this feature decreases with increasing Sr concentration x and has a strong photon energy dependence. It also exhibits a complicated angle dependence. In this report we present a full set of angular-resolved photo

Five experiments examined explicit and implicit memory for information that is congruent with the physical attractiveness stereotype (i.e. attractive-positive and unattractive-negative) and information that is incongruent with the physical attractiveness stereotype (i.e. attractive-negative and unattractive-positive). Measures of explicit recognition-sensitivity and implicit discriminability revea

SiGe Esaki diodes have been realized by rapid thermal diffusion of phosphorous into an SiGe layer grown by ultra-high-vacuum chemical-vapor-deposition on an Si p(+)-substrate for the first time. The phosphorous-doped SiGe forms the n(+)-electrode, while heavily boron-doped Si0.74Ge0.26 and Si substrate is used for the p(+) electrode. The diodes show a peak current density of 0.18 kA/cm(2), a curre

Docetaxel-related skin toxicity, oral and gastrointestinal mucosal toxicity, and changes in blood cell counts were investigated as predictive factors for major infections in 143 women treated with 3-weekly docetaxel (100 mg/m(2)) as second-line therapy for metastatic breast cancer in a randomized trial. Each patient with a major infection (n = 37) was compared with two controls. Skin toxicity (odd