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Despite rapid clinical translation, induced pluripotent stem cell (iPSC)-derived therapies face limited global adoption. Harmonized quality control (QC) remains absent, with even fundamental parameters evaluated inconsistently across laboratories. To address this, we conducted two international Quality Assessment Rounds (QARs): QAR 2019 (18 sites, 11 countries) and QAR 2023 (23 sites, 12 countries

A search for heavy pseudo-scalar (A) and scalar (H) Higgs bosons decaying into a top-quark pair (tt¯) has been performed with 140 fb−1 of proton-proton collision data collected by the ATLAS experiment at the Large Hadron Collider at a centre-of-mass energy of s = 13 TeV. Interference effects between the signal process and Standard Model (SM) tt¯ production are taken into account. Final states with

Dermatan sulfate epimerase 1 (DS-epi1) is a key enzyme in the biosynthesis of the glycosaminoglycan chondroitin sulfate/dermatan sulfate, catalyzing the conversion of glucuronic acid to iduronic acid at the polymer level. Chondroitin sulfate/dermatan sulfate chains are found on at least 32 proteoglycans, many of which are implicated in human diseases and syndromes, as well as in both malignant and

ObjectivesAthletes competing in blind football have consistently been highlighted as at risk for injuries, and potential concussions. This study described the incidence of injuries sustained by athletes competing in blind football (Football 5-a-side) at the London 2012, Rio 2016 and Tokyo 2020 Paralympic Games. This study described injury proportions and incidences by age, period of competition, o

Properties of the underlying-event in pp interactions are investigated primarily via the strange hadrons KS0, Λ and Λ¯, as reconstructed using the ATLAS detector at the LHC in minimum-bias pp collision data at s=13 TeV. The hadrons are reconstructed via the identification of the displaced two-particle vertices corresponding to the decay modes, Λ→π-p and Λ¯→π+p¯. These are used in the construction

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A search for a new heavy boson produced via gluon-fusion in the four-lepton channel with missing transverse momentum or jets is performed. The search uses proton-proton collision data equivalent to an integrated luminosity of 139 fb−1 at a centre-of-mass energy of 13 TeV collected by the ATLAS detector between 2015 and 2018 at the Large Hadron Collider. This study explores the decays of heavy boso

Sveriges totalförsvar står inför ett behov av snabb återuppbyggnad. Det försämrade säkerhetspolitiska läget i Europa, i kombination med ökade och mer komplexa risker för störningar i samhällskritiska funktioner, har gjort detta arbete allt viktigare. Behovet av att säkra tillgången på varor och tjänster som är avgörande för befolkningens överlevnad och samhällets funktionalitet vid kriser och krig

Book review.

INTRODUCTION: Amyloid-induced tauopathy drives clinical decline in Alzheimer's disease (AD). Because age and sex shape tau trajectories, defining patient-centered amyloid thresholds for tauopathy onset could facilitate pre-tauopathy AD identification and aid treatment decisions and prognosis. METHODS: By including two samples (Alzheimer's Disease Neuroimaging Initiative [ADNI, n = 301]; and 18F-AV

Contributing to global urban history, planning theory and the geography of ideas, this article discusses the travels of Henri Lefebvre’s The Right to the City in the wake of May 1968, in France. That year, under the direction of Mario González and Max Baquero, a small team including the Italian architect Vittorio Garatti, French planner Jean-Pierre Garnier and Spanish architect Eusebio Azcue, at t

Olof Palme förknippas ofta med sin utrikespolitik. Men på hemmaplan fattades beslut som fick stora ekonomiska konsekvenser. Fem av dem formade Sverige – och rymmer tydliga lärdomar, skriver Lars Jonung.

Abstract – Background: Neutrophils, previously viewed as short-lived microbial killers, are now recognized as highly adaptable regulators of innate immunity. Advances in transcriptomic, metabolic, and epigenetic profiling reveal their remarkable heterogeneity and ability to adopt microenvironment-specific phenotypes. In the lung, this plasticity gives neutrophils a double role: they fight infectio

The evacuation dynamics of children have been attracting growing research interest. Compared to adult populations, the evacuation behaviours and self-rescue abilities of children can be limited due to their developmental changes. However, considering developmental differences among children of various ages is crucial to avoid oversimplifications. This chapter focuses on evacuation of children in t