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Det råder en global kontinuerlig teknikutveckling som präglar internet med nya innovationer. Många onlinetjänster på internet bedriver sina verksamheter med hjälp av datainsamling av de digitala konsumenterna. Teknikutveckling kräver en insats från både onlinetjänster som behöver vara fortsatt anpassningsbara och digitala konsumenter som behöver begripa vilka konsekvenser utveckling har. Datainsam

Three-part parenting is an approach that social services in Sweden should use in collaboration around a child placed in foster care. It describes how foster home, parents and social services share responsibilities for the welfare of the child. The purpose of this study was to illuminate the state of knowledge about the approach among social workers working with children and adolescents in Sweden.

Combining multiple III-V materials into axial nanowire heterostructures has enabled the fabrication of custom nanowire-based devices useful for a wide range of applications. However, our ability to form axial heterostructures between arbitrary combinations of III-V compounds is impeded by a lack of information on the dynamics of the heterojunction formation process, often resulting in suboptimal h

Human in vitro models of neural tissue with tunable microenvironment and defined spatial arrangement are needed to facilitate studies of brain development and disease. Towards this end, embedded printing inside granular gels holds great promise as it allows precise patterning of extremely soft tissue constructs. However, granular printing support formulations are restricted to only a handful of ma

The labour market consequences of early-onset or congenital disabilities have received little attention in the literature. In this paper, we study the consequences of cerebral palsy (CP), a lifelong early onset disability, and pathways through which it affects labour outcomes. We use data from multiple linked Swedish National Population Registers between 1990 and 2015 and apply both regression and

17 kap. 3 § rättegångsbalken (RB) omgärdas av omfattande begrepps- och teoribildning. Som exempel har det skrivit tre svenska avhandlingar som har bestämmelsen som huvudtema. När det kommer skiljeförfaranden enligt lagen (1999:116) om skiljeförfarande (LSF) är det en omdebatterad fråga i vad mån tvistemålsprocessens begrepps- och teoribildning bör tillämpas analogt. LSF har ingen uttrycklig bestäm

Three new cobalt complexes of the general formula [Co(II)(L)(CH3CN)]2+, where L is one of three pentadentate nitrogen-donor ligands based on the N4Py framework, have been synthesized and characterized. The capacity of the three complexes to effect photocatalytic proton reduction has been examined. Their photocatalytic activities in the presence of [Ru(bpy)3]2+, acting as a photosensitizer, and asc

Heterogeneous integration of III-V narrow bandgap transistors on silicon technology is desirable for high frequency circuit implementations. Such high-speed transistors must, however, scale to large gate widths to be suitable for general circuit design. Averaging among many variable channels is a key challenge for nanowire devices. A simplified, but high-speed compatible, nanowire device process w

Introduction: The rat Vra1 locus, containing glutathione S-transferase alpha 4 (Gsta4), regulates the degeneration of central nervous system (CNS) neurons in toxin-, protein-, and injury-based models. We hypothesize that Piebald Virol Glaxo.1AV1 (PVG) alleles in Vra1 confer protection and increased axonal outgrowth after peripheral nerve injury and repair. Methods: DA rats (n = 14) and DA rats wit

Det ena syftet med denna uppsats är att undersöka skillnaderna mellan den offentliga och den privata sektorn ifråga om arbetstagares kritikrätt. Det andra syftet är att undersöka konsekvenserna för denna rättighet av en dom från Europadomstolen, Fuentes Bobo mot Spanien. Offentligt anställda har en grundlagsskyddad yttrandefrihet, som kan utnyttjas i princip i vilken situation som helst. Begränsni

HIV-2 is less pathogenic compared to HIV-1. Still, disease progression may develop in aviremic HIV-2 infection, but the driving forces and mechanisms behind such development are unclear. Here, we aimed to reveal the immunophenotypic pattern associated with CD8 T-cell pathology in HIV-2 infection, in relation to viremia and markers of disease progression. The relationships between pathological diff

AIMS/HYPOTHESIS: Excess adiposity is differentially associated with increased risk of cardiometabolic disease in men and women, according to observational studies. Causal inference studies largely assume a linear relationship between BMI and cardiometabolic outcomes, which may not be the case. In this study, we investigated the shapes of the causal relationships between BMI and cardiometabolic dis

BackgroundCarotid artery disease is highly prevalent and a main cause of ischemic stroke and vascular dementia. There is a paucity of information on predictors of serious vascular events. Besides percentage diameter stenosis, international guidelines also recommend the evaluation of qualitative characteristics of carotid artery disease as a guide to treatment, but with no agreement on which qualit

BackgroundLow concentrations of serum selenium (Se) and its main transporter selenoprotein P (SELENOP) are associated with a poor prognosis following breast cancer diagnosis. Recently, natural autoantibodies (aAb) with antagonistic properties to SELENOP uptake have been identified in healthy subjects, and in patients with thyroid disease. Given the potential transport disrupting properties, we hyp

Grain boundary interaction with second-phase particles having different degrees of coherency is investigated using the phase field crystal (PFC) method. Both the enveloping and pass-through mechanisms are studied with regards to grain boundary pressure, passage time and interface evolution. It is found that coherent particles exert a stronger retardation effect on grain boundaries compared to incoGrain boundary interaction with second-phase particles having different degrees of coherency is investigated using the phase field crystal (PFC) method. Both the enveloping and pass-through mechanisms are studied with regards to grain boundary pressure, passage time and interface evolution. It is found that coherent particles exert a stronger retardation effect on grain boundaries compared to inco

6G systems, such as Large Intelligent Surfaces, will require distributed, complex, and coordinated decisions throughout a very heterogeneous and cell free infrastructure. This will require a fundamentally redesigned software infrastructure accompanied by massively distributed and heterogeneous computing resources, vastly different from current wireless networks.To address these challenges, in this6G systems, such as Large Intelligent Surfaces, will require distributed, complex, and coordinated decisions throughout a very heterogeneous and cell free infrastructure. This will require a fundamentally redesigned software infrastructure accompanied by massively distributed and heterogeneous computing resources, vastly different from current wireless networks.To address these challenges, in this

The fetal to adult switch in hematopoietic stem cell (HSC) behavior is characterized by alterations in lineage output and entry into deep quiescence. Here we identify the emergence of megakaryocyte (Mk) biased HSCs as an event coinciding with this developmental switch. Single-cell chromatin accessibility analysis reveals a ubiquitous acquisition of Mk lineage priming signatures in HSCs during the

This introduction provides an overview and commentary on the main chapters in the book. The book presents contemporary examples of European research that embrace both rigour and relevance. In doing so, the book demonstrates that both rigour and relevance is alive in entrepreneurship research. Many of the following chapters address agendas that are influenced by pragmatic questions as much as theor

Type 1 diabetes (T1D) is an autoimmune disease that results in the destruction of insulin producing pancreatic β-cells. One of the genes associated with T1D is TYK2, which encodes a Janus kinase with critical roles in type-Ι interferon (IFN-Ι) mediated intracellular signalling. To study the role of TYK2 in β-cell development and response to IFNα, we generated TYK2 knockout human iPSCs and directed