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Soluble urokinase plasminogen activator receptor in plasma is associated with incidence of CVD. Results from the Malmö Diet and Cancer Study.

BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) is a highly sensitive marker that reflects increased inflammation and is positively correlated with pro-inflammatory biomarkers. The aim of this study was to explore the relationship between suPAR, cardiovascular disease (CVD) risk factors and incidence of CVD. METHODS: suPAR was assessed in a random sample of participants (N=569

Low expression of SHP-2 is associated with less favorable prostate cancer outcomes.

ABSTACT: Src homology 2 domain-containing tyrosine phosphatase-2 (SHP-2) is an important regulator of cell signaling because of its ability to dephosphorylate receptors of growth factors as well as the cytokines and tyrosine-phosphorylated proteins associated with these receptors. In the current study, we used four different prostate cancer cell lines: PC3, DU145, LNCaP and LNCaP-IL6+. Tumor speci

Adrenomedullin is a marker of carotid plaques and intima-media thickness as well as brachial pulse pressure.

Adrenomodulin (ADM) is a peptide hormone secreted in response to cellular strain such as ischemia and is believed to have a beneficial effect on the cardiovascular system. However, the epidemiological relationships between ADM and measurements of haemodynamics, arteriosclerosis and atherosclerosis are not well established. The aim of this study was to investigate the association between the mid-re

Low Levels of Apolipoprotein B-100 Autoantibodies Are Associated With Increased Risk of Coronary Events.

OBJECTIVE: Previous smaller studies have indicated inverse associations between autoantibodies to oxidized low-density lipoprotein epitopes, and cardiovascular disease. The present study investigated associations between autoantibodies against the apolipoprotein B-100 peptides p45 and p210, respectively, and risk of incident cardiovascular disease in a large population-based cohort. APPROACH AND

Chromosome 9p21 genetic variation explains 13% of cardiovascular disease incidence but does not improve risk prediction.

OBJECTIVES: To evaluate the proportion of cardiovascular disease (CVD) incidence that is explained by genetic variation at chromosome 9p21 and to test whether such variation adds incremental information with regard to CVD prediction, beyond traditional risk factors. DESIGN, SETTING AND PARTICIPANTS: rs4977574 on chromosome 9p21 was genotyped in 24 777 subjects from the Malmö Diet and Cancer study

Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme

Early growth and differentiation of the pancreatic endoderm is regulated by soluble factors from the pancreatic mesenchyme. Previously, we demonstrated that N-cadherin-deficient mice lack a dorsal pancreas, due to a critical role of N-cadherin in dorsal pancreatic mesenchymal cell survival. Here, we show that restoring cardiac and circulatory function in N-cadherin null mice by cardiac-specific ex

Sources and Diagnostics for Attosecond Science

Ultrafast science refers to physical events that happen on the femtosecond (1 fs=10^-15 s) and attosecond (1 as=10^-18 s) timescales. Generation of attosecond pulses is usually achieved by interacting high-intensity femtosecond pulses with matter (typically gases), in a process called high-order harmonic generation (HHG). Under the correct conditions, this process leads to the creation of sub-fs p

Experimental Investigations of Heat Transfer in a Channel with Ribs and Obstacle

Popular Abstract in English This thesis concerns experiments of heat transfer in a rectangular channel with ribs and an obstacle. Liquid crystal thermography (LCT) is used to record the temperature fields in the experiments. LCT is based on measurement of the color response of a heated surface. When illuminated with a white light, the liquid crystals react to temperature changes by changing color,This thesis presents experimental investigations of local heat transfer in a rectangular channel (aspect ratio AR = 4) with continuous transverse ribs as well as an obstacle. Liquid crystal thermography (LCT) is employed to obtain the temperature fields in the heat transfer experiments. The liquid crystal applied here has a red start at 35°C and a bandwidth of 1°C. The work consists of (1) periodi

Worse glycaemic control in LADA patients than in those with type 2 diabetes, despite a longer time on insulin therapy.

AIMS/HYPOTHESIS: Our aim was to study whether glycaemic control differs between individuals with latent autoimmune diabetes in adults (LADA) and patients with type 2 diabetes, and whether it is influenced by time on insulin therapy. METHODS: We performed a retrospective study of 372 patients with LADA (205 men and 167 women; median age 54 years, range 35-80 years) from Swedish cohorts from Skåne (

Social Capital and Regional Innovation Systems : Bridging approaches and broadening understanding of knowledge sharing and innovation

This doctoral thesis takes as a starting point that geographical location remains fundamental to gain competitive advantage for some types of firms and activities even though economic activity in general has become more global. The region is seen as the key level in which the innovative capability of firms is shaped, coordinated and governed. This is in line with the regional innovation systems (R

Hohfeld relations and spielraum for action

The paper intends to show, (1) that W.N. Hohfeld’s theory of fundamental jural relations is relevant to economic theory, and (2) that Hohfeld’s system can be reconstructed by the concepts of ‘liberty space’ and ‘ability space’, understood as an agent’s Spielraum for action. The first half of the paper is devoted to an exposition of Hohfeld’s system and to the question of its relation to the econom

A comparison of the tetrapyrrole cofactors in nature and their tuning by axial ligands

This chapter illustrates how quantum chemical calculations can be used to elucidate structural and functional aspects of tetrapyrrole cofactors, focusing on porphyrins, cobalamins, coenzyme F430, and chlorophyll. A particular emphasis is put on the biochemical significance of axial ligands, which can tune the function of the tetrapyrroles. With the use of quantum chemical calculations, it is possi

Semiconductor ecosystem to be strengthened

Semiconductor ecosystem to be strengthened Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stän

https://www.lth.se/article/semiconductor-ecosystem-to-be-strengthened/ - 2025-12-19

Formulaic language in academic writing – Investigating the use of prefabs in linguistic abstracts

In this study, the use of prefabricated language in academic abstracts is investigated, as well as the functions of prefabricated expressions (prefabs) in this type of text. By analysing ten abstracts taken from peer-reviewed articles in the field of Linguistics, the amount of prefabs is calculated, and their pragmatic roles investigated. The results are then compared to previous research within t