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Clinicopathological correlates and prognostic significance of KRAS mutation status in a pooled prospective cohort of epithelial ovarian cancer

Background: Activating KRAS mutations are common in ovarian carcinomas of low histological grade, less advanced clinical stage and mucinous histological subtype, and form part of the distinct molecular alterations associated with type I tumors in the dualistic model of ovarian carcinogenesis. Here, we investigated the occurrence, clinicopathological correlates and prognostic significance of specif

Future moisture loads for building facades in Sweden: Climate change and wind-driven rain

This work investigates the prospective impacts of climate change on wind-driven rain (WDR) and walls through simulating the hygrothermal performance of rain screen of common vertical wall constructions for the climatic conditions of Gothenburg in Sweden. While a substantial amount of work has been done on the impact of climate change on the thermal performance of buildings, this paper studies its

Decreased monoamine metabolites in frontotemporal dementia and Alzheimer's disease

The concentrations of the monoamine metabolites homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylglycol (HMPG) in the cerebrospinal fluid (CSF) of patients with clinical frontotemporal dementia (FTD; n = 30), early onset Alzheimer's disease (EAD; n = 33), late onset Alzheimer's disease (LAD, n = 27) and normal controls (n = 31) were determined using HPLC. A

Daily physical activity and its relation to aerobic fitness in children aged 8-11 years.

A positive relationship between daily physical activity and aerobic fitness exists in adults. Studies in children have given conflicting results, possibly because of differences in methods used to assess daily physical activity and fitness. No study regarding daily physical activity and fitness in children has been published, where fitness has been assessed by direct measurement of maximum oxygen

Space weather events in July 1982 and October 2003 and the effects of geomagnetically induced currents on Swedish technical systems

In this paper, we analyse in detail two famous space weather events; a railway problem on 13-14 July 1982 and a power blackout on 30 October 2003. Both occurred in Sweden during very intensive space weather storms and each of them a few years after the sunspot maximum. This paper provides a description of the conditions on the Sun and in the solar wind leading to the two GIC events on the ground.

Leaking roofs in Tunisia

Summary The leaking of water through roofs is a major problem in many parts of Tunisia. As a part of a collaboration between "École N: ionale d'Ingénieurs de Tunis" (E.N.I.T.) and Lund University, Institute of Science and Technology (L.N.T.H.), Sweden, a measuring method has been developed to compare the watertightness of different roofing membranes. With the method, three roof structues with diff

Effect of ticlopidine and prostaglandin E on endotoxin-induced pulmonary platelet sequestration in vivo

Prostaglandin E1 has earlier been shown to decrease pulmonary platelet trapping (PPT) following shock. This experiment was performed to evaluate a new method to study PPT in vivo, and to study the effect of prostaglandin E1 and a new antiplatelet drug (ticlopidine) on PPT in rabbits after i.v. administration of endotoxin. Following platelet labeling with In-111, the rabbits were placed under a sci

Variations of wettability and protein adsorption on solid siliceous carriers grafted with poly(N-isopropylacrylamide)

Poly(N-isopropylacrylamide), a thermally responsive polymer, was end-grafted to mercaptopropyl derivatives of silica gel, plane glass sheets and glass capillary tubing by free radical polymerization of the monomer in 1,4-dioxane at 100 degrees C. The polymer monolayer attached to the glass carriers provided them with thermally controlled wettability registered by two independent methods: direct me

Simulation of soil chemistry and nutrient availability in a forested ecosystem of southern Quebec - I. Reconstruction of the time-series files of nutrient cycling using the MAKEDEP model

The MAKEDEP model is used to reconstruct the time-series input files of deposition, forest growth, uptake and litterfall needed to run the dynamic biogeochemical model SAFE. The amounts and timing of N made available for tree growth is what determines most of the model output. In this paper, the sensitivity Of MAKEDEP to various amounts and timing of N availability, including increased supplies of

Assessing educational priorities in genetics for general practitioners and specialists in five countries: factor structure of the Genetic-Educational Priorities (Gen-EP) scale

Purpose: A scale assessing primary care physicians' priorities for genetic education (The Gen-EP scale) was developed and tested in five European countries. The objective of this study was to determine its factor structure, to test scaling assumptions and to determine internal consistency. Methods: The sample consisted of 3686 practitioners (general practitioners, gyneco-obstetricians, pediatricia

Hepatic and extrahepatic malignancies in autoimmune hepatitis. A long-term follow-up in 473 Swedish patients

Background/Aims: Autoimmune Hepatitis (AIH) is a liver disease which may lead to liver cirrhosis. Cirrhosis is a well-known risk factor for hepatocellular cancer. Lymphoma is a disease, where immune modulating drugs as well as the autoimmune disease itself may contribute to the elevated risk. The aim was to investigate the risks of malignancies in a large cohort of AIH patients. Methods: Four hund

Training Regions Research Strategy 2011-2013

Abstract in UndeterminedOur world is changing and cities and regions are increasingly understood not only asplaces, but also as vital hubs in national and global networks, through which people,capital, goods and services flow to ensure the functioning of society, as we know it. Peopleand capital are increasingly concentrated in these hubs, which aside of positive effects onefficiency also is assoc

Cross-border Unity or Fragmentation of the Kurds - A Qualitative Content Analysis on the KRG’s and the PYD’s Views on National Identity and Statehood

Med en befolkning på cirka 30 miljoner människor är kurderna den fjärde största etniska gruppen i Mellanöstern. Trots detta har kurderna inte sin egen självständiga stat vilket gör dem till en minoritetsgrupp i Turkiet, Irak, Iran och Syrien. Eftersom kurderna är utspridda över fyra olika stater är det av intresse att undersöka hur de hänvisar till varandra i förhållande till idén om att ha en suvWith a population of around 30 million people, the Kurds are the fourth largest ethnic group in the Middle East. Despite this, the Kurds do not have their own independent state which makes them a minority group in Turkey, Iraq, Iran and Syria. Since the Kurds are scattered over four different states it is of interest to examine how they refer to each other in relation to the idea of having an inde

Gräsligt beteende - En kvalitativ studie om hur media presenterar cannabis

The aim of our study was to investigate the image the Swedish media present of cannabis and in particular hasch. We gathered all articles published during one month in the year 2002 and in 2012 in three major newspapers in Sweden. The newspapers examined where Dagens Nyheter, Aftonbladet and Metro. Through a social constructive perspective and discourse analysis as method we divided the content in

All publicitet är bra publicitet, eller?

Denna studie syftar till att bidra till en bredare bild av varumärkeskommunikation med fokus på sambandet mellan provokativ marknadsföring samt attityder och beteenden. Frågeställningarna är utformade för att undersöka potentiella konsumenters upplevelser av provokativ marknadsföring och hur de talar om det i förhållande till varumärket. Studien bygger på ett teoretiskt ramverk baserat på strategiThis study aims to contribute to a broader picture of brand communication with a focus on the relationship between provocative marketing and attitudes and behaviours. The questions are designed to investigate potential consumers' experiences of provocative marketing and how they talk about it in relation to the brand. The study is based on a theoretical framework based on strategic brand manag

Valsedelns Empatiska Påverkan - En experimentell enkätstudie om selektiv empati i politiska in- och utgrupper

Denna studie sökte svar på huruvida människor tenderar att känna mer empati för personer som tillhör deras politiska ingrupp än de som befinner sig i utgruppen, och därmed om empati är selektivt i förhållande till politiska in- och utgrupper. Empati definieras här som (1) kognitiv empati, (2) affektiv empati, och (3) empatisk oro. Urvalet bestod av personer som identifierar sig som socialdemokrateThis study sought to answer whether people have a higher tendency to feel empathy towards people who are part of their own political ingroup, rather than those who are in the outgroup, meaning, if empathy is selective in relation to political in- and outgroups. Empathy is defined here as (1) cognitive empathy, (2) affective empathy, and (3) empathic concern. The sample consisted of people who symp

Musikens Magi: en kvantitativ studie i hur olika musikgenrer påverkar studenters prestation i matematikuppgifter.

Den här studien ämnade att undersöka huruvida olika musikgenrer; blues , klassisk musik och rockmusik, samt utan musik (kontrollgrupp), påverkar prestation i matematik. 52 personer deltog i studien och de blev alla tilldelade en av de fyra musikgenrerna genom en mellangruppsdesign. Studien bestod av två test. Första testet var ett standardiserat matematiktest bestående av 12 frågor (refereras tillThis study aims to investigate how listening to different music genres; blues, classical, and rock, as well as no music (control condition), affects mathematical performance. 52 individuals participated in the study and all were assigned to one out of the four music conditions using a between-subject design. The study includes two tests. The first test was a 12 question standardized mathematics te

Anställningsskyddets osäkra framtid - En uppsats om undantaget i turordningsreglerna

Inom svensk arbetsrätt är (SFS 1982:80) lagen om anställningsskydd den centrala lagstiftningen som reglerar anställningsform och hur en uppsägning får ske. Arbetstagaren har turordningsreglerna i 22§ Lag om anställningsskydd som skydd och i det anciennitetsprincipen (senioritetsprincipen), då arbetsgivaren anfört arbetsbrist inom verksamheten som uppsägningsskäl. Turordningsreglerna har varit In Swedish labor law (SFS 1982: 80), the Employment Protection Act is the central legislation that regulates the form of employment and how a termination may take place. The employee has the rules of priority in section 22 of the Employment Protection Act as protection and in the seniority principle, when the employer cites lack of work as a reason for termination. The rules of priority have been

Who am I without my stuff?

In a world where migration has dramatically increased over the last 30 years, migrant consumers have become an important market actor. When migrant consumers geographically relocate they potentially experience changes in their identity, while different factors influence their acculturation to the host culture. Consumer acculturation literature within Consumer Culture Theory has studied this topic

A Bland New Way To Imitate? A Qualitative Study Exploring the Phenomena of Blands Through Consumers' Perceptions

Thesis Purpose: The purpose of this thesis is to explore the phenomenon of blands – A rise of brands that potentially adhere to a similar blueprint while claiming to be disruptive, unique and extraordinary. Moreover, this thesis aims to create an understanding of how consumers perceive blands as well as well as how value is created. Methodology: The methodology takes a social constructivist stan