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Extracellular vesicles (EVs) are membrane enclosed biological nanoparticles released by cells. In the past two decades, EVs have gained a lot of attention due to their role in numerous biological processes. However, their small nature complicates isolating them from biological fluids with cumbersome techniques, such as ultracentrifugation. Acoustic trapping is a technique that uses ultrasonic stan
According to traditional research in subjective well-being, the more pleasant emotions we experience, the more satisfied with life we are. But according to newer research, our physical and mental health, including satisfaction with life, also depends on the emotional diversity between the positive and negative emotions we experience, and the difference between the emotions we desire and those we a
Studiens syfte var att undersöka om det fanns ett samband mellan anställningsotrygghet och upplevt psykiska välmående med det sociala samspelet mellan kollegor som en medierande effekt. Detta undersöktes genom en webbaserad enkät, där upplevt psykiskt välmående, anställningsotrygghet och det sociala samspelet mättes med konstruktestade formulär. Deltagarna (N=87) var anställda i livsmedelsbutiker The purpose of the study was to examine if there is a covariance between job insecurity and the experienced mental well-being with the factor social interaction between co-workers as a mediating effect. This was studied through a web survey where experienced mental well-being, social interaction and job insecurity was measured with construct validated surveys. The participants (N=87) were employee
Metodutveckling i sökandet efter mikroplaster i tarminnehåll från tumlare Ett allt växande problem är ökande mängden mikroplaster i havet och hur de påverkar havslevande organismer. Mikroplast är små plastbitar som är mellan 0,1 - 500 mikrometer. De är uppdelade i primära och sekundära mikroplaster. Det har visat sig att båda typerna ackumuleras och stannar kvar i vattenlevande ekosystem där plasAn ever-growing problem is the increasing amount of microplastics in the sea and how they affect marine organisms. Microplastics are small pieces of plastic that are between 0.1 - 500 micrometres. They are divided into primary and secondary microplastics. Primary microplastics are those plastics that are intentionally produced to be microplastics. Secondary microplastics are generated from larger
Det har sagts att alla arkitekturepoker brukar nå sitt bottenmärke någonstans runt 30 år. Under en praktik på ett arkitektkontor upplevde jag det på egen hand när jag arbetade med ett område i Stockholm. Strategin för området är att riva stora delar av dess bebyggelse från 80- och 90-talet. Jag uppfattar strategin som ett uttryck för en allmän impopularitet av arkitekturen från denna period — den
This essay concerns the complementation of the English emotive verbs like, love, hate and prefer. In English, gerund-participial and infinitival complements often receive semi-synonymous semantic interpretations when complementing emotive verbs. All the while, both complement types supposedly convey separate semantic interpretations, resulting in that they commonly appear in contexts expressing ha
Registered Nurses (RNs) are in the immediate position to provide End-of-life (EOL) care and counselling for patients and families in various settings. However, EOL-care often creates feelings of uncertainty and inadequacy linked to inexperience, lack of education, and attitude. To identify and describe factors associated with RNs' attitudes towards EOL-care, and to identify whether and how these a
We performed a national population-based study of all patients diagnosed with diffuse large B-cell lymphoma (DLBCL) in Sweden in 2007–2014 to assess treatment intent and risk of relapsed/refractory disease, including central nervous system (CNS) relapse, in the presence of competing risks. Overall, 84% of patients started treatment with curative intent (anthracycline-based) (n = 3550, median age 6
Objective: Congenitally corrected and surgical atrial redirected transposition of the great arteries (TGA) represents states where the morphological right ventricle serves as a systemic ventricle (S-RV). The S-RV is prone to failure, but data on medical treatment on this problem is limited. The purpose of this study was to evaluate the survival in adults with S-RV, with or without heart failure tr
Objectives: To describe the clinical and ultrasound characteristics of adnexal torsion. Methods: This was a retrospective study. From the operative records of the eight participating gynecological ultrasound centers, we identified patients with a surgically confirmed diagnosis of adnexal torsion, defined as surgical evidence of ovarian pedicle, paraovarian cyst and/or Fallopian tube twisted on its
Objectives: The National Board of Health and Welfare in Sweden published the national guidelines for Parkinson's Disease 2016. The aim of this study was to summarize this evidence review and development of the guidelines, focusing on the economic evaluation of device-aided therapies (deep brain stimulation, pump-based infusion of levodopa-carbidopa intestinal gel or apomorphine) for Parkinson's di
Type 1 diabetes is a chronic autoimmune disease requiring insulin treatment for survival. Prolonged duration of type 1 diabetes is associated with increased risk of microvascular complications. Although chronic hyperglycemia and diabetes duration have been considered as the major risk factors for vascular complications, this is not universally seen among all patients. Persons with long-term type 1
The aim was to describe food intake over time in children and adolescents, with respect to age and gender. The present study was a repeated cross-sectional study using self-reported data from a health questionnaire. Data were collected from the School Health Services in south-east Sweden from 44 297 students, 10, 13-14 and 16 years of age, 48 % girls and 52 % boys from 2009/2010 to 2015/2016. Repo
In 2013, the drinking water for one-third of the households in Ronneby, Sweden, was found to be contaminated by perfluorinated alkyl substances (PFAS, >10,000 ng/L) from Aqueous Film Forming Foam (AFFF). In utero PFAS exposure can influence birth weight, but little is known about the effects at very high levels. This study aimed to examine the association between in utero PFAS exposure and birth w
Background: Osteoporosis is an underdiagnosed and undertreated disease worldwide. Recent studies have highlighted the use of simple vertebral trabecular attenuation values for opportunistic osteoporosis screening. Meanwhile, machine learning has been used to accurately segment large parts of the human skeleton. Purpose: To evaluate a fully automated deep learning-based method for lumbar vertebral
While a broad spectrum of technologies is integrated in everyday life and routines, most research on ageing, health and technology has focused on attitudes toward and adoption of digital technologies including e-health, or home based monitoring systems. The aim of this study was to explore differences and similarities in attitudes and experiences with different types of technologies and developmen
BACKGROUND: Little is known about the costs of HIV care in Ethiopia.OBJECTIVE: To estimate the average per person year (PPY) cost of care for HIV patients with and without anti-retroviral therapy (ART) in a district hospital.METHODS: Data on costs and utilization of HIV-related services were taken from Arba Minch Hospital (AMH) in southern Ethiopia. Mean annual outpatient and inpatient costs and c
Objective: This paper analyses intergenerational relationships in Sweden during the corona pandemic, with a special focus on practices of care. The research question is: How is care between generations – between grandparents, adult children and grandchildren – done during pandemic conditions? Background: In Sweden, where an extensive welfare state provides affordable child- and eldercare, the coro
Elastic fibers containing elastin play an important role in tendon functionality, but the knowledge on presence and function of elastin during tendon healing is limited. The aim of this study was to investigate elastin content and distribution in intact and healing Achilles tendons and to understand how elastin influence the viscoelastic properties of tendons. The right Achilles tendon was complet
