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Targeting tumour vasculature by inhibiting activin receptor-like kinase (ALK)1 function

Angiogenesis is a hallmark of cancer and is now a validated therapeutic target in the clinical setting. Despite the initial success, anti-angiogenic compounds impinging on the vascular endothelial growth factor (VEGF) pathway display limited survival benefits in patients and resistance often develops due to activation of alternative pathways. Thus, finding and validating new targets is highly warr

Surface Properties of Antigen-Antibody Complexes

In this paper, the authors show that liquid-liquid partition chromatography in an aqueous two-phase system offers unique possibilities of comparing the overall surface properties of intact antibodies in solution before and after binding of antigen. The authors demonstrate that the surface properties of antigen-antibody complexes are dependent on the variable regions of the antibodies, the nature o

Affinity fractionation of lymphocytes using a monolithic cryogel.

A new type of continuous, supermacroporous, monolithic, cryogel affinity adsorbent was developed, allowing specific fractionation and separation of human peripheral blood lymphocytes in a chromatographic format. The affinity adsorbent was used to design a novel cell separation strategy, which was based on the interaction of protein A from Staphylococcus aureus with cells bearing IgG antibodies on

How to apply

Please discuss the courses you want to apply for with your supervisor before completing the application form. If the number of applicants exceeds available places, applicants are prioritized as follows:PhD students from the Department of Psychology, Lund UniversityPhD students from the Faculty of Social Sciences, Lund UniversityPhD students from other faculties at Lund UniversityExternal PhD stude

https://www.psy.lu.se/how-apply - 2026-05-01

A recent intermezzo at the Ribosome Club

Two sets of ribosome structures have recently led to two different interpretations of what limits the accuracy of codon translation by transfer RNAs. In this review, inspired by this intermezzo at the Ribosome Club, we briefly discuss accuracy amplification by energy driven proofreading and its implementation in genetic code translation. We further discuss general ways by which the monitoring base