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High-throughput proteomics, based on the microarray platform, requires stable, highly functional components that will yield a highly sensitive read-out of low, abundance protein. Although antibodies are the best characterized binding molecules for this purpose, only a fraction of them appear to behave satisfactorily in the chip format. Therefore, high demands need to be placed on their molecular d
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The purposes of this review are to summarize studies of cross-sections of autopsied whole muscles from previously physically healthy males and to focus on the cause of the ageing atrophy. The ageing atrophy begins around 25 years of age and thereafter accelerates. This is caused mainly by a loss of muscle fibres, and to a lesser extent by a reduction in fibre size, mostly of the proportion of the
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The influences of different types of cleaning agents on a polysulphone ultrafiltration (UF) membrane which had been used to treat oily waste water were investigated. The cleaning experiments were performed with samples of polysulphone membranes removed from a commercial plant in which oily waste water is treated. Five different cleaning agents were used and their influences on the fluxes were inve
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The CHIC Collaboration has performed a series of fermion interferometry experiments to study the space-time evolution of the emission sources in intermediate energy heavy ion reactions. Correlation functions of non-identical particles have allowed us to extract model independent information on the sequence of emission (chronology) of the particles. In this contribution, we discuss the order of emi
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Neural precursor cells transplanted to adult retina can integrate into the host. This is especially true when the neural precursor rat cell line RN33B is used. This cell line carries the reporter genes LacZ and green fluorescent protein (GFP). In grafted rat eyes, RN33B cells are localized from one eccentricity to the other of the host retina. In the present study, whole-mounted retinas were analy
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In 1982 the Swedish diplomat and philologist Gunnar Jarring (1907-2002) donated his unique collection of manuscripts from Eastern Turkestan to the University Library in Lund. The article presents this extremely rich collection.
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The sympathetic nervous system has been shown to exert a trophic influence on vascular smooth muscle cells (VSMC). Therefore, we studied the growth-regulating effects of the sympathetic cotransmitters ATP, neuropeptide Y (NPY), and norepinephrine (NE). ATP in concentrations of 1-100 microM greatly increased the incorporation of [3H]thymidine in VSMC from rat aorta and vena cava. ATP also increased
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The natural history of carotid artery disease was studied in a retrospective study of 609 angiograms performed during 1969-1979 on patients who had subsequently not been operated on. The indication for angiography differed, but was aimed at clarifying suspected cerebrovascular events. 578 patients could be followed-up after a median time of 10.4 years (0-22). The median survival time after angiogr
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During the development of a new circulatory support system, we have used different animal models with and without heart failure for hemodynamic testing. As the normally functioning heart does not always allow for proper evaluation of a circulatory support system, a good and adjustable animal heart failure model is needed. The aim of the study was to develop a left ventricular failure model in calv
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This article is the first part (Chroococcales and Oscillatoriales) of a study of little known planktic and metaphytic cyanoprokaryotes (cyanophytes, cyanobacteria) from ponds, lakes and water reservoirs in southern Africa. Thirty-three species were observed, of which 24 are presented with comments. Ten new species are defined, and one species, originally described as a taxonomic form, is recombine
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In this study, the geographical variation of the mortality rate in mid-Sweden was studied. Data on mortality from all causes and mortality from cardiovascular diseases, cerebrovascular diseases, ischaemic heart disease (IHD) and non-cardiovascular diseases for men and women 45-74 years of age living in 76 communities in mid-Sweden were obtained from the National Bureau of Statistics. After age sta
