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The utility of the GHOST(3) cell assay has been evaluated for testing coreceptor use of primary human immunodeficiency virus type 1 (HIV-1) isolates. GHOST(3) cells were derived from the human osteosarcoma cell line, HOS, and have been engineered to stably express CD4 and one or another of the chemokine receptors CCR3, CCR5, CXCR4, Bonzo, or the orphan receptor BOB. The Indicator cell line carries
The fine-structure splittings of highly excited F-states in Cs were measured using high-resolution laser spectroscopy. The 12 and 132F states were found to be inverted with splittings ?E (122F)=-522(3) MHz and ?E (132F)=-416(3) MHz.
Anti-proliferative drugs have been used for immunosuppression since the introduction of clinical transplantation. Most transplant centres include azathioprine (Aza) and cyclosporine (CyA) in their standard regimens, despite several controlled studies having failed to confirm the benefit of this combination. Aza is still. the most commonly used anti-proliferative drug, although no major differences
In a long-term prospective study, 39 preterm children born before 35 completed weeks of gestation and 23 full-term children were followed up at 19 years of age. Information about somatic and mental health was obtained through interviews and confirmed by medical records. Self-esteem and quality of life were assessed from the subjects' perspective. Significantly more preterms than full-terms had som
The current study was made to develop a biosensor based on a single-chamber microbial fuel cell in which anaerobes were retained in the anode compartment separated from the cathode compartment by a proton exchange membrane. In the sensor a replaceable anaerobic consortium was used for analyzing biodegradable organic matter. The anaerobes acted as biocatalysts in oxidizing organic matter and transf
This study aimed to examine the association between the interval from ejaculation to analysis and epididymal and accessory sex gland function in relation to sperm motility. Ejaculates from 1079 men assessed for infertility were analyzed according to World Health Organization guidelines. Biochemical markers were measured in semen to assess the function of the epididymi;s (neutral alpha-glucosidase
The breakpoints in chromosome 22 were determined in five children with Philadelphia-positive chronic myeloid leukemia. All had rearrangements within the major breakpoint cluster region (M-bcr). Four patients had breakpoints in the 5' region of M-bcr (zones 1-3), whereas one had a rearrangement in the 3' region (zone 4). The patient with the 3' rearrangement was the only one to develop a lymphoid b
BACKGROUND: Collagenous colitis is a disease characterized by chronic watery diarrhea, and on microscopic examination of colonic tissue, a typical thickening of the subepithelial collagen layer is seen. The etiology and pathophysiology behind this disease state are largely unknown. METHODS: We have used in situ hybridization and immunohistochemistry to study the expression of transforming growth f
Popular Abstract in Swedish Avhandlingen studerar olika aspekter av internationell ekonomi knutna till utländska direktinvesteringar, produktionsmönster och handelsflöden. Dessa behandlas i ljuset av en globalt tilltagande internationalisering såväl som fördjupad ekonomisk integration på regional nivå. I kapitel två studeras effekten av utländska direktinvesteringar av multinationella företag på vThe study analyses various aspects of international economics related to foreign direct investment, trade and specialisation. These issues are considered in view of the increased internationalisation - through trade and foreign direct investment - in recent decades. Special interest is devoted to the effects of economic integration. Chapter two examines the importance of FDI and country capabiliti
Tomatoes are a rich source of antioxidants; and they are commonly used for meat cooking in Mediterranean countries. The effects of tomato antioxidants on the formation of carcinogenic/mutagenic heterocyclic amines were investigated. A liquid model system containing as precursors creatinine, glucose and glycine in molar concentrations comparable to those present in bovine meat (chemical model syste
Den här rapporten utgår från en litteraturstudie avseende vissa trafiksäkerhetsfrågor som genomfördes vid Rättssociologiska avdelningen i Lund, på uppdrag av Vägtrafikinspektionen i Borlänge, under våren 2005. Studien syftade till att kartlägga befintlig kunskap avseende möjligheterna att med ökad trafikövervakning och strängare sanktioner uppnå högre grad av regelefterlevnad i trafiken. Studien s
Background and Purpose - Regular endurance exercise has been shown to reduce the age-related increase in arterial stiffness that is thought to contribute to cardiovascular risk. The aim of this study was to evaluate the influence of age and habitual physical activity on carotid artery wall thickness and stiffness in a population of young to middle-age subjects at low cardiovascular risk. Methods -
Popular Abstract in Swedish Ultraljudsundersökningar av bäckenbottens fysiologi och förlossningsrelaterade skador i mellangården ¨Perineum, det sista hinder som fostret vid förlossningen har att öfvervinna, drager sig ofta blodigt sargad tillbaka ur den hårda brottningen, äfven om under densamma en rådig och insigtsfull hand blifvit räckt till dess bistånd. Den biståendes anseende och rykte kan hRepair of obstetric perineal tears is one of the most frequent procedures in surgical practice. Despite repair such tears may result in anal and urinary incontinence and prolapses of the pelvic floor, problems in need of surgical repair later in life. Descriptions of the structures injured during vaginal delivery and their topographic relations in the perineum are missing in most textbooks. Trans
