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Triptans are agonists at 5-HT1B and 5-HT1D (where 5-HT is 5-hydroxytryptamine; serotonin) receptors and cause vasoconstriction of isolated blood vessels. The aim of the present study was to determine vasoconstrictor potency (EC50) of triptans in human coronary and cerebral arteries and to examine whether there was any relationship with the maximal plasma concentrations (Cmax; nM) of the drugs achi
To evaluate the potential use of tree-ring data as a proxy for fire activity at the scale of a large boreal region, we analyzed a set of regional tree-ring chronologies of Siberian larch (Larix sibirica L.), a spatially implicit annual fire record, and monthly climate data for the Komi Republic for the period 1950-1990. In most years, annually burned area was below 0.001% of the republic's foreste
A model for a special configuration in triaxial odd-odd nuclei is constructed which exhibits degenerate chiral bands with a sizable rotation, a manifestation of dynamical spontaneous symmetry breaking. A quantum number obtained from the invariance of the model Hamiltonian, which characterizes observable states, is given and selection rules for electromagnetic transition probabilities in chiral ban
A 120 kHz echo sounder, with two split-beam transducers, was used horizontally to monitor the behaviour of 0+ roach Rutilus rutilis, from June to August, in field enclosures. 0+ roach outside the vegetated area of the enclosures were registered both as schools and as single swimming fish. Combining echo counting and tracking with direct observation of echograms, an estimate of relative abundance o
In this paper propagation of transient electromagnetic waves in a reciprocal bi-isotropic medium is presented. The constitutive relations are convolution integrals with two susceptibility kernels that model the medium. The propagation problem is solved by the introduction of a wave-splitting technique. This wave-splitting is used to solve the propagation problem using either an imbedding approach
1. I tested the hypothesis that the potential for non-lethal effects of predators are more important for overall performance of the fast-growing exotic signal crayfish (Pacifastacus leniusculus Dana) than for the slower growing native noble crayfish (Astacus astacus L.). I further tested if omnivorous crayfish switched to feed on less risky food sources in the presence of predators, a behaviour th
Cosmological investigations, using high-redshift quasi-stellar object (QSO) absorption spectra, of possible variations of the fine-structure constant (alpha) require very accurate laboratory wavelengths for a number of resonance transitions from several different species. A change in alpha could be detected as a shift in the wavelengths of atomic transitions in the QSO systems and to accurately de
The oxidation of Pd(111) leads to an incommensurate surface oxide, which was studied by the use of scanning tunneling microscopy, surface x-ray diffraction, high resolution core level spectroscopy, and density functional calculations. A combination of these methods reveals a two-dimensional structure having no resemblance to bulk oxides of Pd. Our study also demonstrates how the atomic arrangement
OBJECTIVE: To describe the long-term influence of meniscectomy on pain, functional limitations, and muscular performance. To assess the effects of radiographic osteoarthritis (OA), gender and age on these outcomes in patients with meniscectomy. DESIGN: 159 subjects (35 women), mean age 53 years, were examined 19 (17-22) years after open meniscectomy. Self-reported symptoms and function were assess
A photochemistry study on nitrous oxide making use of site-selective excitation of terminal nitrogen, central nitrogen, and oxygen 1s-->3pi excitations is presented. The resonant Auger decay which takes place following excitation can lead to dissociation of the N(2)O(+) ion. To elucidate the nuclear dynamics, energy-resolved Auger electrons were detected in coincidence with the ionic dissociation
Purpose: We aimed to investigate associations between serum levels of the advanced glycation endproduct methylglyoxal-derived hydroimidazolone (MG-H1) and retinopathy in a sample of patients with type 1 diabetes. Methods: We conducted a cross-sectional study in a Scandinavian ophthalmology outpatient clinic on 61 randomly selected patients with type 1 diabetes. Blood samples and retinal photograph
Urokinase plasminogen activator (uPA) is involved in the activation of different proteases which participate in the degradation of extracellular matrix, thereby enhancing the invasive capacity of tumour cells. uPA has been shown to be of prognostic importance in breast cancer. We have analysed uPA with a new luminometric immunoassay (LIA), applicable in cytosol samples routinely used for oestrogen
EU negotiations are characterized bythe coexistence of a bargaining and a problem-solving approach. The permanence of EU negotiations discourages tough bargaining behaviour, as does the prevalence of strong consensus norms. On the other hand, evidence exists of very confrontational behaviour that often leads to lowest common denominator solutions. We argue that the mode of negotiation to be found
The Torrabaai-Koigabmond Complex (southern Kaoko Belt, Namibia) consists of three main intrusive rock types including metaluminous hornblende- and titanite-bearing quartz diorites, metaluminous hornblende- and biotite-bearing granodiorites and peraluminous garnet- and muscovite-bearing leucogranites. Uranium-Pb zircon data obtained on the granodiorites and leucogranites indicate concordia upper in
OBJECTIVE: The aim of this study was to investigate any association between vaginal carriage of Mycoplasma hominis and genital signs and symptoms, other microbial findings, and some risk behavior factors in women with and without bacterial vaginosis. STUDY DESIGN: Women who had attended two family planning clinics and a youth clinic for contraceptive advice were divided depending on the result of
The neotropical, freshwater copepod Notodiaptomus iheringi decreased the growth of small colonies in cyanobacteria-dominated plankton, indicating that they can be efficiently ingested and that they may represent an important food source for this copepod in reservoirs dominated by cyanobacteria. Cultured, colonial, toxic Microcystis aeruginosa was not affected, indicating that toxicity may cause a
The recent interest in photodynamic therapy of human prostate cancer is accompanied by a need for techniques for in vivo monitoring of optical and physiological characteristics. We propose time-of-flight (TOF) spectroscopy in combination with Monte Carlo evaluation as a reliable optical technique for quantitative assessment of absorption, scattering, hemoglobin content and tissue oxygenation in th
Nanofiltration (NF) has attracted increasing attention during recent years due to the development of new applications. The advantage of NF compared with reverse osmosis (RO) and ultrafiltration (UF) is that it is possible to separate organic substances from some types of salts. It is, furthermore, also possible to separate different kinds of salts due to the negatively charged groups on the membra
In a unifying way, the doorway mechanism explains spectral properties in a rich variety of open mesoscopic quantum systems, ranging from atoms to nuclei. A distinct state and a background of other states couple to each other which sensitively affects the strength function. The recently measured superscars in the barrier billiard provide an ideal model for an in-depth investigation of this mechanis
