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Streptococcus agalactiae and Streptococcus pyogenes are two related human pathogens causing different diseases. This thesis focuses on a number of surface proteins expressed by S. agalactiae and S. pyogenes and, more specifically, the molecular and biological characterization of these proteins. The first paper describes the novel Blr protein of S. agalactiae, which together with the previously de

The MAX IV storage rings, currently under construction in Lund, Sweden, will use third harmonic cavities operated passively to lengthen the bunches and alleviate collective instabilities. These cavities are an essential ingredient in the MAX IV design concept and are required for achieving the final design goals in terms of stored current, beam emittance, and beam lifetime-such performance challen

Depression and bipolar disorder, collectively known as mood disorders, are devastating, common and often chronic illnesses. Imaging studies of patients with mood disorders have demonstrated structural changes in several brain regions implicated in mood regulation. Furthermore, bipolar disorder is associated with white matter abnormalities and post mortem analysis of brain tissue from patients with

The rise of MEMS and µTAS techniques has created a whole new family of microfluidic devices for a wide range of chemical and biomedical analyses to be performed on small Lab-on-a-chip platforms. The operations often include small samples of particle or cell suspensions on which separation, mixing, trapping or sorting is performed. External fields and forces are used for these operations, and this

Extreme climatic events such as the El Nino Southern Oscillation profoundly affect many plants and animals, including amphibians, which are strongly negatively affected by drought conditions. How amphibians respond to exceptionally high precipitation as observed in La Nina events, however, remains unclear. We document the correlation between the exceedingly wet 2010-2012 La Nina and community-leve

In this work the sensitivity-increasing effect of single-walled carbon nanotubes (SWCNTs) in amperometric biosensors, depending on their average length distribution, was studied. For this purpose the SWCNTs were oxidatively shortened and subsequently length separated by size exclusion chromatography. Transmission electron micrographs of different fractions of SWCNTs were collected. Diaphorase "wir

Laminar burning velocity of lean hydrogen + air flames at standard conditions is still a debated topic in combustion. The existing burning velocity measurements possess a large spread due to the use of different measurement techniques and data processing approaches. The biggest uncertainty factor in these measurements comes from the necessity to perform extrapolation to the flat flame conditions,

Background: Thrombolysis is a common method in the treatment of lower extremity bypass graft occlusion. The purpose of this study was to investigate the results of thrombolytic therapy in the management of acute bypass graft occlusion and to identify risk factors for technical failure and amputation. Methods: All patients at two tertiary referral centers undergoing thrombolysis for acute graft occ

In this article we look at examples of three predominant kinds of Swedish retail places – the pedestrianised city centre, the neighbourhood centre and the regional shopping mall – all of which play important (winning or losing) roles in contemporary retail development. This investigation is based on an empirical study of the Malmö region (in southern Sweden) and the findings suggest that the diffe

Objectives - Aneurysmal subarachnoid hemorrhage (SAH) is frequently associated with delayed neurological deterioration (DND). Several studies have shown that DND is not always related to vasospasm and ischemia. Experimental and clinical studies have recently documented that it is possible to diagnose and separate cerebral ischemia and mitochondrial dysfunction bedside. The study explores whether c

OBJECTIVE: Describe the clinical course and predictors of change in self-reported outcomes and objectively assessed physical function over time in middle-aged subjects at high risk of, or with knee osteoarthritis (OA). METHODS: We examined 259 subjects (mean age 52.6 [SD 10.4]) at mean 18 and 25 years after previous meniscectomy and 50 population-based age- and sex-matched reference subjects with

Background The safety of long-acting beta(2) agonist (LABA) therapy in asthma remains controversial but no large scale analyses have been published of LABA safety in children. Methods The frequency of asthma-related deaths and hospitalisations following formoterol use in children (4-11 years) and adolescents (12-17 years), compared with non-LABA treatment, was assessed in all AstraZeneca-sponsored

Purpose: We investigated the distribution of cannabinoid receptor subtypes 1 and 2 in the detrusor of different species and studied the effects of cannabinoid receptor 1 and 2 agonists on bladder function. Materials and Methods: Cannabinoid receptor 1 and 2 expression was studied with Western blot and immunohistochemistry in rat, monkey and human detrusors. Co-staining was done for markers of sens

Objectives. Cone beam computed tomography (CBCT) was introduced to Norwegian dental clinics in 2007. The aim of the study was to investigate how dental clinics use this imaging modality, including factors related to workflow and image quality, and to evaluate dentists' opinions on and experiences of using it. Materials and methods. A web-based 59-item questionnaire regarding the clinical use of CB

Electrochemical oxidation is an effective method in removal of organic pollutant from high salinity waste-water (NaCl), by producing active chlorine at anode or hydrogen peroxide at cathode. To solve the existing problems including low efficiency, high cost and energy consumption, a Ti/SnO2-Sb anode (TSSA)-air diffusion cathode (TSSA-ADC) system was investigated for methyl orange (MO) removal from

OBJECTIVE-Using the genome-wide association approach, we recently identified the glucokinase regulatory protein gene (GCKR, rs780094) region as a novel quantitative trait locus for plasma triglyceride concentration in Europeans. Here, we sought to study the association of GCKR variants with metabolic phenotypes, including measures of glucose homeostasis, to evaluate the GCYR locus in samples of no

This article explores the “question of the animal” in Swedish artist Ann-Sofi Sidén’s project Queen of Mud, executed between 1988 and 2004. Queen of Mud revolves around a naked female creature, smeared from top to toe in wet mud, which interferes in human affairs and challenges thereby common assumptions about the human/animal divide and the human-animal continuum. By reading Queen of Mud over aga