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We consider initial value problems (IVPs) where we are interested in a quantity of interest(QoI) that is the integral in time of a functional of the solution. For these, we analyze goal orientedtime adaptive methods that use only local error estimates. A local error estimate and timestepcontroller for step-wise contributions to the QoI are derived. We prove convergence of the error in theQoI for

BACKGROUND: The diagnosis of chronic obstructive pulmonary disease is based on the presence of persistent respiratory symptoms and chronic airflow limitation (CAL). CAL is based on the ratio of forced expiratory volume in 1 s to forced vital capacity (FEV1:FVC) after bronchodilation, and FEV1:FVC less than the fifth percentile is often used as a cut-off for CAL. The aim was to investigate if incre

AIMS: Identifying subjects at high and low risk of atrial fibrillation (AF) is of interest. This study aims to assess the risk of AF associated with electrocardiographic (ECG) markers linked to atrial fibrosis: P-wave prolongation, 3rd-degree interatrial block, P-terminal force in lead V1, and orthogonal P-wave morphology. METHODS AND RESULTS: P-wave parameters were assessed in a representative Fi

Phillipskurvan, dvs sambandet mellan inflation och arbetslöshet, är central i den penningpolitiska debatten. Högre arbetslöshet förutsätts vara kopplad till lägre inflation. Det är mot denna bakgrund som Sune Karlsson och Pär Österholm (2020) gett sig ut på jakt efter den svenska Phillipskurvan i första numret av Ekonomisk Debatt 2020. I sin jakt har Karlsson och Österholm enbart utgått från svens

Context. Reconstructing the Galactic evolution of lithium (Li) is the main tool used to constrain the source(s) of Li enrichment in the Galaxy. Recent results have suggested a decline in Li at supersolar metallicities, which may indicate reduced production. Aims. We exploit the unique characteristics of the Gaia-ESO Survey open star cluster sample to further investigate this issue and to better co

The rapidly expanding stream of path development studies recognises that translating observations from past paths to conscious path creation requires conceptually linking agency to path development frameworks. Actors frame issues about and for the future, coordinate their actions in the present and make sense of what may have transpired in the past. The main objective of the paper is to explore th

Aim: Head injury is the most common trauma occurring in syncope. We aimed to assess whether syncope as cause of head-trauma affects short-and long-term prognosis. Methods: From a database retrospective analysis of 97,014 individuals attending Emergency Department (ED), we selected data of patients with traumatic head injury including age, gender, injury mechanism, brain imaging, multiple traumas,

BACKGROUND: Urothelial carcinoma is the predominant (95%) bladder cancer subtype in industrialized nations. Animal and epidemiologic human studies suggest that hormonal factors may influence urothelial carcinoma risk. METHODS: We used an analytic cohort of 333,919 women from the European Prospective Investigation into Cancer and Nutrition Cohort. Associations between hormonal factors and incident

The growing acceptance and recognition of Surface Guided Radiation Therapy (SGRT) as a promising imaging technique has supported its recent spread in a large number of radiation oncology facilities. Although this technology is not new, many aspects of it have only recently been exploited. This review focuses on the latest SGRT developments, both in the field of general clinical applications and sp

Rather than exogenous endowments, natural resources can be seen as economically exploitable resources thanks to knowledge improvements. This underscores the need to understand why some natural resource abundant countries are able to develop their own technologies while others are not. We tackle this issue by looking at the evolution of engineering faculties and graduate engineers from 1850 to 1939

The interaction of ultrathin single-crystalline IrO2(110) films with the gas phase proceeds via the coordinatively unsaturated sites (cus), in particular Ircus, the undercoordinated oxygen species on-top O (Oot) that are coordinated to Ircus, and bridging O (Obr). With the combination of different experimental techniques, such as thermal desorption spectroscopy, scanning tunneling microscopy (STM)

Combustion of ammonia (NH3) as a carbon-free alternative fuel has been recently widely studied, with vast majority of the burning velocity data obtained at room temperature. In the present study, the laminar burning velocity SL of NH3/air mixtures has been measured at unburnt gas temperature Tu from 298 K to 448 K, covering equivalence ratios from 0.85 to 1.25 and at 1 atm using the heat flux meth