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BACKGROUND: In this study, we combine proteomics with functional parameters and imaging to examine potential biomarkers that may identify patients at risk of developing persistent lung sequelae following coronavirus disease 2019 (COVID-19).METHODS: We performed multiplex profiling of serum and collected clinical data from intensive care unit (ICU)-treated patients with COVID-19 (n=43) at 4 and 10

Background: Palliative care (PC) can alleviate suffering and improve quality of life. Yet, disparities persist, particularly in Honduras. Training efforts in PC for non-health caregivers have proven to reduce burnout and stress while enhancing the quality of life for both caregivers and patients. Purpose: This study aimed to explore the feasibility of a PC training program for non-health caregiver

Acute dyspnoea is one of the most common presenting symptoms in the emergency department (ED) and has a variety of underlying causes. Calprotectin is a neutrophil activation marker associated with adverse outcomes in acute cardiovascular and infectious diseases. However, the usefulness of calprotectin in the risk stratification of patients with acute dyspnoea is unknown. The objectives were to, in

Background: Hemodynamically obstructive coronary plaques may contain more vulnerable plaque characteristics than nonobstructive lesions. Objectives: The authors aimed to assess whether pressure-wire–based physiologic indices in nonculprit lesions are associated with vulnerable plaque characteristics. Methods: In the PROSPECT II study, patients with recent myocardial infarction underwent coronary a

The overall aim of this research project is to investigate whether new service value interventions on an individual level can lead to maintained or even increased mobility through ageing, but also to identify reduced costs for society (e.g. costs for transport services) and a transition from private car use to more sustainable transport. The purpose of this study is therefore to identify challenge

Peritoneal dialysis (PD) is a kidney replacement therapy for patients with end-stage renal disease. It is becoming more popular as a result of a rising interest in home dialysis. Its effectiveness depends on several physiological and technical factors, which have led to the development of various computational models to better understand and predict PD outcomes. In this review, we traced the evolu

In this article, I present a modified reliabilist theory of knowledge which purports to solve many of the problems currently facing standard reliabilism. With the help of a dispositionally construed reliabilist theory of knowledge and justification (DRK and DRJ), tentative responses to the following problems for reliabilism are offered: The New Evil Demon Problem, The Clairvoyance Problem, The Mr.

Satellite-based Synthetic Aperture Radar Interferometry (InSAR) represents a promising supplement to traditional Structural Health Monitoring (SHM) methods, offering a non-invasive solution that eliminates the need for sensor installations and provides extensive spatial coverage. The European Ground Motion Service (EGMS), developed by the European Space Agency under the Copernicus program, marks a

Background and Purpose: Malignant melanoma is the most lethal form of skin cancer, characterised by a poor survival rate. One of the key factors driving the aggressive growth of melanoma cells is the elevated expression of the proto-oncogene Bcl-3. This study aims to optimise, evaluate and characterise a second-generation Bcl-3 inhibitor, using melanoma as a model to demonstrate its potential ther

Introduction: Attention-deficit/hyperactivity disorder (ADHD) frequently exists alongside psychiatric comorbidities. The coexistence of somatic diseases and ADHD constitutes a growing field of research. Method: This study aimed to examine the prevalence of common somatic diseases in adolescents with ADHD and compare them with those in adolescents without any psychiatric diagnoses. A cross-sectiona

Background: Psychiatric disorders have been associated with venous thromboembolism (VTE). However, to our knowledge, no nationwide study has examined the familial association between VTE and psychiatric disorders. Objectives: We took a pedigree-based approach and examined the risk of psychiatric disorders in offspring from extended pedigrees according to the densities of VTE in pedigrees. Methods: