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Introduction Head and neck cancer of unknown primary (HNCUP) is a rare condition whose prognostic factors that are significant for survival vary between studies. No randomized treatment study has been performed thus far, and the optimal treatment is not established. Objective The present study aimed to explore various prognostic factors and compare the two main treatments for HNCUP: neck dissectio

Background: No previous paediatric study has evaluated the frequency of diagnostic disagreement between clinical standard histopathological assessment (CSHA) and retrospective, independent, histopathological assessment (RIHA) of gastrointestinal Graft-Versus-Host Disease (GI-GVHD). Methods: In a retrospective cohort study, based on gastrointestinal biopsies collected from allogeneic HSCT-treated c

The EC Directive 2013/59/Euratom states in article 56 that exposures of target volumes in nuclear medicine treatments shall be individually planned and their delivery appropriately verified. The Directive also mentions that medical physics experts should always be appropriately involved in those treatments. Although it is obvious that, in nuclear medicine practice, every nuclear medicine physician

The pharmaceutical approach to skin disease has been hugely successful, but despite effective drugs being available and used, there are still vast numbers of people who continue to have some level of persisting skin disease and continue to experience quality of life (QoL) impairment. So the question that needs to be answered, while we await further advances in our drug-based armamentarium, is how

Background: Patients in the late stages of parkinsonism are highly dependent on others in their self-care and activities of daily living. However, few studies have assessed the physical, psychological and social consequences of caring for a person with late-stage parkinsonism. Patients and methods: Five hundred and six patients and their caregivers from the Care of Late Stage Parkinsonism (CLaSP)

Vitamin D (Vit-D), an essential nutrient, interacts with different drugs including chemotherapeutic agents like busulphan, an alkylating agent used for conditioning prior to stem cell transplantation. The correlation between Vit-D plasma levels and busulphan clearance was investigated in an uncontrolled prospective study in patients and mice. Plasma 25(OH)D levels were measured and busulphan pharm

Concrete is the most commonly used material worldwide, often associated with an irreversible production process and waste generation at the end-of-life. As such, the concrete industry holds large untapped potentials for moving towards more circular economy (CE) practices. Product service system (PSS) offerings incentivize CE through extending product use, improving product performance and developi

Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is bas

Progress in the power conversion efficiency of solar cells based on metal-halide perovskite semiconductors has been astonishing for the past years. During their development, transient effects have been observed that gave rise to an uncertainty associated with the determination of device performance from current density-voltage (J-V) measurements. This effect becomes visible in a dependence of the

In the wake of global crises concerning, for example, inequalities, migration, pandemics, and the environment, ethical concerns have come to the fore. In this thematic issue, we are especially interested in the role that the planning, design, and materialities of the built environment can take in relation to ethics, and we present four different openings or themes into urban ethics that we also th

This article aims to understand how the introduction of blue-green solutions affects ethical concerns and expectations of an urban environment. Blue-green solutions are complementary technical solutions, introduced into urban water management, in order to deal with the impact of urbanisation and climate change. These kinds of solutions establish new affordances that have an impact on everyday life

INTRODUCTION: The pituitary gland has a high expression of somatostatin receptors (SSTRs) and is therefore a potential organ at risk for radiation-induced toxicity after 177Lu-DOTATATE treatment.OBJECTIVE: To study changes in pituitary function in patients with neuroendocrine tumors (NETs) treated with dosimetry-based 177Lu-DOTATATE to detect possible late toxicity.METHODS: 68 patients from a phas

PURPOSE: Current hypothesis regarding the mechanism of active tear drainage is based on studies performed ex vivo or under nonphysiological conditions. Novel ultra-high-frequency ultrasound has the advantage of generating images with superior resolution, enabling measurements of low flow in small vessels, and the tracking of tissue motion in real time. The purpose of this study was to investigate

Introduction: Sclerostin, an inhibitor of bone formation, has emerged as a potential negative regulator of glucose homeostasis. We aimed to investigate if serum sclerostin associates with insulin sensitivity, beta cell function, prediabetes or metabolic syndrome in healthy men. Materials and methods: Serum sclerostin was measured in basal and insulin-stimulated samples from 526 men without diabete

The understanding of diesel sprays is very important to enable a better and cleaner marine engine design, but unfortunately little knowledge is openly available on marine engine fuel sprays. In this paper, evaporating sprays for medium speed marine engines were studied in a constant volume combustion chamber by performing optical measurements through Schlieren and Mie diagnostic techniques. The ef

Glyphosate (GLY), N-(phosphonomethyl) glycine, is the most widely used herbicide in the world. It is a broad-spectrum herbicide, also used in crop desiccation. Agricultural workers may be occupationally exposed and general populations may be exposed to GLY mainly through diet. We studied the kinetics of GLY by measuring the parent compound and its metabolite aminomethylphosphonic acid (AMPA) in ur