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Executive compensation is increasingly being linked to ESG outcomes. This paper examines whether ESG targets are consistent with shareholder welfare. Using granular information on compensation contracts of Swedish CEOs, we show that ESG and financial targets are competing. ESG-linked compensation is 5 percentage points more common in well-governed firms and 6.3 percentage points more likely for CE

OBJECTIVE: Quantitative susceptibility mapping (QSM) is a semi-quantitative method, i.e., only differences in magnetic susceptibility can be quantified. The lack of a stable internal reference hampers longitudinal and systematic comparisons among subjects. In this study, a phase-based approach, enabling the use of an external reference, is proposed.MATERIALS AND METHODS: By modeling the object geo

Dynamic glucose-enhanced (DGE) MRI is an emerging imaging technique that provides information on sugar uptake with contributions from delivery (perfusion), transport (membrane permeability), and metabolism in vivo. DGE MRI contrast reflects changes in water magnetization caused by changes in sugar concentration, which can be detected through chemical exchange between water protons and sugar hydrox

PURPOSE: Direct Saturation Dynamic Glucose Enhanced (DS-DGE) MRI is a novel technique that utilizes low B 1 strength and short saturation pulse duration to measure the effect of enhanced T 2 relaxation caused by the infusion of D-glucose, resulting in linewidth broadening of the direct water saturation (DS) signal in the water saturation spectrum (Z-spectrum). In this simulation-supported protoc

INTRODUCTION: Treatment response in high grade gliomas (HGG) is influenced by O6-methylguanine-DNA methyltransferase promoter methylation (MGMTpm). Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) is a non-invasive approach for potential molecular tumor characterization, although previous studies have reported inconsistent results for MGMTpm. This study investigates fl

From technoscience fiction to research, human encounters with animals and machines have unfolded and exposed issues of identity, affection, trust, intimacy and how artificial systems settle what kinds of relationships are possible. This is because relations matter to humans, and what makes others significant for us is not set in stone: we have co-evolved ways of communicating and constructing rela

This thesis investigates the use of performance bounds in radar signal processing, with particular emphasis on the Cramér-Rao bound (CRB) and its misspecified and Bayesian variants, the MCRB and the BCRB. These bounds characterize fundamental limits on estimation accuracy and can therefore be used to assess the performance attainable under a given signal model. However, they can also be used prosp

Using nationwide register data, individuals aged 15–60 years registered as suspects of firearm homicide, attempted firearm homicide, or conspiracy/preparation to commit such offenses (firearm homicide+) between 2000 and 2020 were matched to population controls. Conditional logistic regression examined the association between immigrant background and registered suspicion of firearm homicide+, adjus

PURPOSE: Patients with the traditional definition of multimorbidity, with 2 or more chronic diseases, are a very large and heterogeneous group who differ considerably depending on which set of disorders they suffer from. This paper describes the baselines characteristics of the GerMoT cohort and investigates if the GerMoT inclusion criteria could be used to identify a subgroup of multimorbid patie

INTRODUCTION: Although there are more women than men working in the healthcare system in Europe, reports of gender-related inequities within the healthcare workforce are still emerging. Our study aimed to gather insights from women, representing different healthcare professions, who work in the field of geriatric medicine and gerontology, to better understand their perspectives and experiences.MET

Medan opinionsmätningarna duggade tätt låg en annan fråga och skvalpade under ytan i valrörelsen: om framtiden för AI-bolagen och hur datacenter ska byggas och förses med el i det svenska landskapet. Här finns en skiljelinje som kan ha påverkat valutgången och kommer göra det framöver.

En av valrörelsens stora snackisar var om Liberalerna skulle klara spärren. Mycket tyder på att L åtnjöt en lika strid ström av taktiska röster från Moderatsympatisörer som Kristdemokraterna gjorde vid valet 2010.

Teamwork in complex organizational contexts is frequently characterized by a lack of clarity regarding which relationships are relevant at any given moment, that is, by in-situ membership ambiguity, often enacted as subgrouping. Leadership is particularly relevant in such moments, as an organizing force capable of enacting the full team as the in-situ relevant membership. Contemporary leadership tTeamwork in complex organizational contexts is frequently characterized by a lack of clarity regarding which relationships are relevant at any given moment, that is, by in-situ membership ambiguity, often enacted as subgrouping. Leadership is particularly relevant in such moments, as an organizing force capable of enacting the full team as the in-situ relevant membership. Contemporary leadership t

Gene therapy with AAV vectors carrying genes for neuropeptide Y and its receptor Y2 has been shown to inhibit seizures in multiple animal models of epilepsy. It is however unknown how the AAV serotype or the sequence order of these two transgenes in the expression cassette affects the actual parenchymal gene expression levels and the seizure-suppressant efficacy. To address these questions, we com

Epilepsy is a central nervous system disorder causing uncontrollable seizures. One-third of patients do not respond to current medications, necessitating new treatments. This study targeted epileptogenesis, the process leading to chronic epilepsy, using human mesenchymal stem cells (MSCs) in a rodent model. MSC transplantation can positively affect neurodegenerative diseases by modifying inflammat

I dag används ofta dukmembran tillverkade av termoplast i vägtunnlar eller andra undermarksanläggningar för att avleda läckande vatten från berget. Trafikverket har flera funktionskrav för dukmembran, varav ett berör brandskydd. Generellt gäller att en högre brandklass ofta innebär försämrade egenskaper inom andra områden, såsom styrka och tålighet. Därför används i många projekt dukmembran med br

Bacteria deploy virulence factors to subvert host immunity; yet the molecular details of these interactions often remain limited. Here, we reveal the structure and host interactome of the Streptococcus pyogenes nuclease A (SpnA). We characterize the structure and dynamics of SpnA using hydrogen-deuterium exchange mass spectrometry and single-particle electron cryo microscopy, yielding the first st

Educational change is not simply a matter of reform. The political project of changing education may itself turn education into a site of struggle over what education should be, what kinds of human beings – and, by extension, what kind of society – it is expected to produce, and what futures it should make possible. This thesis explores the Iranian state’s policy project of changing education afte