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Amyloida fibriller är aggregat av självassocierande proteiner som tillsammans skapar ett tätpackat inre med hög ordningsgrad. Dessa fibriller är ofta förknippade med neurodegenerativa sjukdomar, t.ex. Alzheimers- och Parkinsons sjukdom. I dagsläget saknas botemedel för dessa sjukdomar och därav finns det intresse för att studera amyloida fibriller. Grundläggande forskning om exempelvis fibrillernaAmyloid fibrils are aggregates of self-assembled peptides and proteins that forms a highly ordered and densely packed core of β-strands stacking perpendicular to the length of the fibril. Amyloid fibrils of the protein α-synuclein (α-syn) are associated with Parkinson’s disease. This study aims at contributing to the physiochemical basis of α-synuclein aggregation and dissolution, mainly in terms

Nanoparticles have gained considerable attention in the last decades, especially in the medical field. The nanoparticles could enter our bodies from anywhere in the surrounding environment and interact with objects in our biological fluids. However, there is little knowledge about this process. The protein competes for the nanoparticle's surface area, forming “corona” made of different proteinNanoparticles are small particles that the human eye cannot detect. They are particles of matter that are found in the natural world and created as a consequence of human activity. For a particle to be classified as a nanoparticle, it should have a diameter between 1 and 100 nm, larger particles up to 500 nm could be also classified as nanoparticles. Their submicroscopic size allows them to have d

In Sweden there has been an increase in neuropsychiatric disabilities over the last few years.This has led to many discussions, both in science and politics as well as amongst regular people. But the most valid and knowledgeable source of information about life with a neuropsychiatric disability is the people living with it themselves. The aim of this paper is to research individuals' experien

The purpose of this research was to investigate the mediating role of managerial cognition in the adoption and innovation of business models triggered by emerging digital technologies. Firstly, we explored how managers cognitively conceptualize emerging digital technologies (i.e., Artificial Intelligence, Blockchain, Cloud Computing, Internet of Things and Big Data, and the Metaverse) as enriched

Although states have begun to regulate influencer activities in areas such as advertising and consumer protection, that is not the case in tax law. This research analyses various Tax Authority’s guidelines on the matter and concludes that the rules already in place in most jurisdictions are applied to influencers’ activities. This demonstrates that a tax system with solid foundations can adapt to

I dagsläget står textilindustrin i Sverige inför flera utmaningar relaterat till dess negativa miljöpåverkan och brist på cirkularitet. Ett identifierat ämne inom detta område är klyftan mellan e-handlare av kläder och second hand-organisationer eller andra mottagare av kläder. Klyftan skapar en affärsmöjlighet i form av en affärsmodell för en digital tjänst som kan stödja cirkularitet genom att kToday, the textile industry in Sweden faces several issues regarding its negative environmental impact and lack of circularity. One identified topic within this area is the gap between fashion e-retailers and second-hand organisations or other receivers of garments. The gap creates a business opportunity in terms of a business model for a digital service that can support circularity by connecting

Aktivitetsanalys av enzymet PARP16 och dess koppling till cancerterapi Cancer är ett ord som troligtvis berör på ett eller annat sätt. Vare sig om man drabbas själv eller inte, så påverkar det alla om det så bara är en närstående till en som blivit drabbad. Studier inom proteinkemin har länge varit av stor betydelse då proteiner spelar en nyckelroll i DNA reparation. En enzymfamilj som är av storResearch in cancer is an ongoing project which not only includes finding more efficient treatment therapies, but also achieving a greater knowledge of how proteins of interest are targeted by inhibitors. Furthermore, research in this field can give us greater knowledge about the development of cancer cells if they are modified. One enzymatic protein family, the PARPs, has been widely studied for d

Purpose: The purpose of this thesis is to understand how a privatization process affects a company’s institutional logic in the presence of path dependence mechanisms, and to delineate the implications this has on the firm’s value creation strategy. Theoretical Perspectives: This thesis builds upon general ownership theories from the perspective of institutional logics. To these perspectives, path

Patent law has been prevalent in climate change discussions, as a factor linking technology, Intellectual Property Rights (IPRs) and the climate crisis. The inventive step, its set threshold and the environmental benefits for the assessment of its current state, are one of the paths where patent law can act as a potential promoter of green technologies. This paper aims to asses how patent law can

Euroscepticism is an old, but nevertheless still dangerous, phenomena for the European Union and for further European integration. Now more than ever, in the wake of Brexit and other crises of the 2000th century, public Euroscepticism is on the rise throughout the European Union member states. Notably, it has been determined that the rise is particularly large within rural areas. The residents of

This thesis scrutinises the concept of the European Super League in light of EU competition law and aims to provide an answer to the question whether the rules on prior authorisation by FIFA and UEFA infringe Article 101 and/or Article 102 TFEU, and whether the European Super League itself infringes Article 101 TFEU. The outcome of this thesis is that both questions must be answered in the affirma

This research aimed to explore the experiences of Lagos State residents during COVID-19 and the relationship between COVID-19 reportage in Lagos State and ethnic inter-relationship. The goal is to understand media influence in a society from the perspectives of people directly influenced by the COVID-19 media frames. This thesis is the first research to explore ethnic polarization in Lagos State w

Patients under the jurisdiction of the Scania Region of Sweden have since 2014 had the ability to choose their care provider regarding opioid substitution treatment, OST. This ability to choose has come from the advancements of the New Public Management, NPM, within Swedish health care. The goal of which has been to increase the availability of OST, as well as to strengthen the patient's auton

Spelreklam utgör idag en majoritet av all marknadsföring som sker. Måttfullhetskravet i spellagen utgör ett krav att spelaktörer ska iaktta måttfullhet vid marknadsföring av spel till konsumenter. Måtfullhetskravet har idag en vägledning som innebär rekommendationer och riktlinjer. Måttfullhetskravet ska förbli flexibelt i spellagen och vid sanktioner ska en helhetsbedömning göras. Detta lämnar 15Gambling advertising today constitutes a majority of all marketing that takes place. The requirement of moderation in the Gambling Act is a requirement that gambling players must observe moderation when marketing games to consumers. The requirement of moderation today has a guide that entails recommendations and marketing guidelines. The moderation requirements must remain flexible in the Gambl

Syfte Syftet med föreliggande studie var att undersökte om det finns en skillnad i upplevd rösthälsa i åldersgrupperna 65-70, 71-75 och 76-80, och ett samband mellan upplevd rösthälsa och omfattning och upplevelse av social delaktighet bland individer mellan 65 och 80 år. Metod En webbenkät avseende upplevd rösthälsa och social delaktighet skapades för allmänt friska deltagare som för närvarande Purpose The aim of this study was to examine whether there was a difference in subjective vocal health in age groups 65-70, 71-75 and 76-80, and an association between subjective vocal health and the extent and experience of social participation among individuals aged 65 to 80 years. Method An online questionnaire regarding subjective vocal health and social participation was distributed to subj

Circular economy has recently become a central part of European policy, bridging the environmental and economic policy domains closer than ever in an attempt to fulfil enhanced environmental ambitions. As economic operators seek to adopt innovative solutions, the issue of how established legal frameworks hamper or facilitate them becomes central. This thesis examines this point in relation to on

Denna masteruppsats baseras på en jämförande undersökning beträffande egennamn och benämningar i den norska och den svenska översättningen av J. K. Rowlings Harry Potter and the Philosopher’s Stone (1997). Syftet med denna uppsats är att undersöka skillnaderna i översättningsval mellan språken vad gäller kategorierna egennamn och benämningar samt om valen varierar beroende på kategori. Uppsatsen b

Transylvania’s countryside, characterized by a mostly agrarian society with a rich multicultural heritage is being threatened by Romania’s tendencies of chaotic modernization and rapid urbanization. This research aims to find a viable solution for sustaining the cultural, natural, and social environment in rural Transylvania, by analysing the potential of tourism development. Integrated Rural Tour

Bakgrund: Kontroll av gastrisk residualvolym (GRV) via aspiration sker på intensivvårdsavdelningar med syfte att säkerställa tillräcklig nutritionstillförsel och utvärdera risken för komplikationer relaterade till enteral nutrition (EN). Studier visar på oenighet huruvida stor GRV faktiskt ökar risken för negativa effekter, dessutom varierar rutiner för GRV-mätning gällande teknik, frekvens och mBackground: Checking gastric residual volumes (GRV) by aspiration is a method practiced on intensive care units with the purpose of lowering the risk of complications due to enteral nutrition (EN) as well as to ensure adequate delivery of EN. Studies have shown disagreement whether large GRVs increase the risk of negative effects, also the methods of measuring vary by technique, frequency and amou