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We study the problem of tracking or disturbance rejection for signals beyond the Nyquist frequency in the sampled-data context. Given the well-established sampling theorem, one is inclined to infer that it is possible to track or reject only those signals below the Nyquist frequency. However, such a high-frequency signal may be detected as an aliased signal, and this opens a new possibility in tra

The loading of macroelements such as, dissolved organic carbon (DOC), totalnitrogen (N) and total phosphorus (P) from terrestrial soils to aquatic systems isincreasing in the northern hemisphere. This phenomenon has several ecologicaland biogeochemical consequences for inland and coastal water systems, which arelinked to bacterial cycling of DOC, N and P. During growth, bacteria assimilatemacroeleThe loading of terrestrially derived macroelements, such as dissolved organic carbon (DOC), total nitrogen (N), and total phosphorus (P), to inland and estuarine waters is increasing in the northern hemisphere. Thesemacroelements often limit heterotrophic bacterioplankton metabolism (production and respiration), which in turn influence food web structures, exchange of greenhouse gases between the

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) may result in severe bleeding, particularly fetal and neonatal intracranial haemorrhage (ICH). As a result, FNAIT requires prompt identification and treatment; subsequent pregnancies need close surveillance and management. An international panel convened to develop evidence-based recommendations for diagnosis and management of FNAIT. A rigorou

Few could have foreseen the consequences when the British Parliament, in 1807, passed the Slave Trade Act that sought to abolish slave imports into the British Empire. From population decreases in the British Caribbean to increased prices in the Cape Colony, historical evidence suggests that the effects of the Act were felt far and wide even though commercialization of slaves was still possible wi

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The objective of this review is to assess benefits and harms of non-invasive respiratory support for themanagement of transient tachypnea of the newborn.

Through geological time, cyanobacterial picoplankton have impacted the global carbon cycle by sequestrating CO 2 and forming authigenic carbonate minerals. Various studies have emphasized the cyanobacterial cell envelopes as nu

Severe lung inflammation and alveolar hemorrhage can be life-threatening in systemic lupus erythematosus (SLE) patients if not treated early and aggressively. Neutrophil influx is the driver key of this pathology, but little is known regarding the molecular events regulating this recruitment. Here, we uncover a role for IL-16/mir-125a in this pathology and show not only that IL-16 is a target for

The paper describes work done using synchrotron light to investigate the microstructure and how it behaves in 3D when a load is applied. Two different cast iron materials with different matrix structures and graphite morphologies were investigated; SiMo51, which is basically a spheroidal iron (SGI) alloyed with Si and Mo, and a lamellar graphite iron (LGI). The tensile test specimens were loaded i

Overexpression of recombinant proteins in bacteria may lead to their aggregation and deposition in inclusion bodies. Since the conformational properties of proteins in inclusion bodies exhibit many of the characteristics typical of amyloid fibrils. Based on these findings, we hypothesize that the rate at which proteins form amyloid fibrils may be predicted from their propensity to form inclusion b

Mouth ulcers are the most common ulcerative condition and encompass several clinical diagnoses, including recurrent aphthous stomatitis (RAS). Despite previous evidence for heritability, it is not clear which specific genetic loci are implicated in RAS. In this genome-wide association study (n = 461,106) heritability is estimated at 8.2% (95% CI: 6.4%, 9.9%). This study finds 97 variants which alt

In this study, a multiphysics model is presented that predicts creep in three months old concrete cylinders subjected to drying. The model includes concrete hydration, and a moisture transport model with relative humidity as the driving potential. These parameters are important to include in order to simulate creep. The model was implemented in the finite element software COMSOL Multiphysics. The