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This article uses empirical investigation of regional hydrogen investments and strategies in Northern Europe to develop a new conceptual approach to regional industrial path development which foregrounds politics and power as explanatory factors in understanding the logics, processes and outcomes of path development. This conceptualisation departs from Evolutionary Economic Geography approaches to
Introduction: Two large multicentre European hospital networks have estimated vaccine effectiveness (VE) against COVID-19 since 2021. Aim: We aimed to measure VE against PCR-confirmed SARS-CoV-2 in hospitalised severe acute respiratory illness (SARI) patients≥20 years, combining data from these networks during Alpha (March–June)- and Delta (June–December)dominant periods, 2021. Methods: Forty-six
Stingless bees (Meliponini) are important pollinators in tropical ecosystems and very abundant in the Bolivian Yungas region; yet little is known about their foraging behavior and floral preferences. In this study, we combined melissopalynology, pollen analysis from honey, with plant-pollinator interactions network to investigate foraging behavior and niche overlap of three rescued stingless bee s
Constans (CO), one of the key transcription factors of the zinc finger family, plays a crucial role in the photoperiodism-dependant flowering pathway. A systematic structural and functional analysis of the CO gene homologs need to be conducted in mango cultivars with contrasting bearing behaviors: ‘Amrapali’ (regular) and ‘Chausa’ (irregular). RNA-Seq leaf transcriptomes were mined for CO homologs
Antibiotics are crucial in treating infectious diseases, particularly in intensive care unit patients, but they can lead to side effects such as ototoxicity. A mechanism for this is antibiotics targeting mitochondrial components in eucaryotic cells, due to their resemblance of those in bacteria. Here we investigate how five classes of antibiotics (carbapenems, fluoroquinolones, aminoglycosides, gl
Anticipation entails contemplating the beneficial and harmful impacts of scientific and technological progress. Anticipation has a long history in science, technology, and innovation policy partly due to future impacts of scientific progress being inescapable. The link between anticipation, an undertheorized concept, and human rights law is yet to be fully explored. This paper links anticipation t
In an article in this journal, Katherine Drabiak argues that green lighting genome editing of human embryos is contrary to "fundamental human rights law." According to the author, genome editing of human embryos violates what we should recognize as a fundamental human right to inherit a genome without deliberate manipulation. In this reply article, we assess Drabiak's legal analysis and show metho
This paper investigates resilient performance of Air Traffic Management with future Artificial Intelligence (AI)-based tools. A case study was performed on an early prototype of an AI-enabled Flight Information Service (FIS) tool, using a survey of flight instructors and air traffic controllers, and a focus group with controllers with flying experience. The study focused on what characterizes good
Spontaneous symmetry breaking, driven by nonadiabatic electron-nuclear coupling, can lead to geometric com plexity in molecules and solids. While structural distortion from symmetry breaking occurs in femtoseconds, the timescale to lift electronic state degeneracy has remained elusive. We use the vibrationally resolved attosecond chronoscope to capture the electronic symmetry breaking induced by t
Attosecond photoelectron interferometry, based on the measurement of photoelectron spectra generated by a two-colour field, provides access to the photoionisation dynamics of quantum systems. In general, due to the entanglement between the wave function of the emitted photoelectron and that of the parent ion, the dynamics driven by the infra-red field in the photoion can affect the properties of t
Axonal injuries commonly contribute to poor functional outcomes following traumatic brain injury (TBI). To assess cerebral blood flow (CBF) and energy metabolic disturbances in a TBI model of widespread axonal injury, we exposed 105 adult mice to the central (midline) fluid percussion injury (cFPI) diffuse TBI model, or sham injury, and used 9.4 T magnetic resonance (MR) arterial spin labeling (AS
Despite the centrality of economic theories (including political economic theories) in human geographic research, there is a massive shortage of courses covering this topic in many human geography departments. In this paper, we use the example of a third-semester elective MSc course in political economic theory designed for students in human geography to contribute to this point. The course aims t
AIM: Right ventricular (RV) function determines symptom burden and clinical outcomes in pulmonary hypertension (PH). Global wasted work (GWW) quantifies mechanical inefficiencies in RV performance associated with elevated afterload, but is inadequately characterized in precapillary PH. We assessed the association of GWW with echocardiographic indices of RV remodeling, RV-PA coupling and invasive h
