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This architectural thesis investigates a general system for a sustainable tourism-related built environment in the Swedish mountains. With a growing interest in hiking and nature-based tourism, the Swedish mountain landscape has become an increasingly popular destination, while at the same time serving as important grazing land for reindeer. This calls for careful development and reduced environme

Machine Learning for Air Charge Estimation: A Residual Error Approach

Improving the efficiency of combustion engines is crucial from an environmental perspective, serving as a complement to the transition towards the electrification of transportation. To optimize combustion efficiency, the amount of air in the cylinders needs to be estimated, which today is done by gray box-models based on traditional physics. This thesis examines the possibility of complementing th

Physical Human–Robot Interaction Using a Mobile Manipulator

This thesis investigates human–robot co-manipulation in which a mobile manipulator assists a person in handling and maneuvering a jointly held object. A cooperative control strategy is developed that enables the robot to guide its motion by the human forces transmitted through a jointly held object. In this framework, the mobile base provides the primary movement while the manipulator maintains ob

6D Pose Estimation and Calibration for Autonomous On-Orbit Servicing using the OOS-SIM

Reliable six-degree-of-freedom pose estimation is a key requirement for autonomous on-orbit servicing (OOS), in which a robotic spacecraft performs tasks such as inspection, maintenance, and life extension of other satellites in orbit. However, generating trustworthy ground truth for algorithm development remains challenging. This thesis investigates calibration, sensor evaluation, and sensor fusi

Bloodstream Infections and Antimicrobial Resistance in The Gambia : Continuous Surveillance from a Tertiary Care Center

Antimicrobial resistance (AMR) poses a major threat to global health, with limited surveillance data available from western sub-Saharan Africa. After reports of high rates of methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum beta-lactamase (ESBL) in bloodstream infections at The Gambia’s sole tertiary hospital, we present follow-up data after enhancements in microbiology cap

The Role of RB1 and Secondary Genomic Changes in the Development of Spindle Cell and Pleomorphic Lipomas

Spindle cell lipomas (SCL) and pleomorphic lipomas (PL) are today considered a single tumor entity (SCLPL). Atypical SCLPL, in contrast, represents a recently recognized related but distinct entity. Here we explored the correlation between genomic features and morphological aspects of SCLPL and atypical SCLPL and the role of the RB1 gene in tumor development. Seventy-one samples from 68 patients w

Perceptual discrepancies in the experience and reporting of violence against children are more pronounced among social workers compared to laypeople

When violence against a child is reported to authorities, it is crucial that its severity is communicated effectively and evaluated accurately by professionals. This study, conducted in two phases, investigated perceptual differences in calibration and accuracy regarding psychological and physical violence against children among parents, social workers, and laypeople. In Phase 1, parents who had w

What can mission-oriented innovation policy learn from China?

The concept of a mission-oriented innovation policy has been discussed for several years now, with definitions and conceptual understanding gradually emerging. Although focused on grand societal challenges, i.e. on a particular type of problem that has been receiving attention only in the last couple of years, the discussion and the design of mission-oriented innovation policy can still draw on pa

Medial temporal lobe Tau-Neurodegeneration mismatch from MRI and plasma biomarkers identifies vulnerable and resilient phenotypes with AD

BACKGROUND: The heterogeneity of Alzheimer's disease (AD) and lack of well-validated markers of non-AD factors (e.g. TDP-43) present a substantial challenge for therapeutics. Our prior work showed discordance between tau (T) and neurodegeneration (N) identified non-AD factors in AD through multi-modality imaging. Here we tried a simplified approach using plasma ptau217 and medial temporal lobe (MT

Cardiac Rehabilitation Registries as Tools for Quality Improvement and Research : Insights From the SWEDEHEART-CR registry

Cardiac rehabilitation (CR) is a well established intervention for secondary prevention after myocardial infarction (MI), yet substantial variability in CR delivery and patient outcomes persists globally. This review provides an in-depth overview of the SWEDEHEART-CR registry, a comprehensive Swedish national quality registry that has facilitated continuous quality improvement and clinical researc

Exposome project for health and occupational research night shift cohort (EPHOR-NIGHT) : a unique resource to advance research on night shift work and chronic disease

Purpose The EPHOR-NIGHT cohort was established to investigate how night shift work influences biological pathways and chronic disease risk using a comprehensive working-life exposome approach, focusing on cardiometabolic, mental health, cognitive and biological ageing outcomes. Participant The cohort includes 937 workers aged 20–65 years (88%female), primarily from the healthcare sector (96%) in S

New Cam Profile Design Approach, Analysis and Testing for Extreme High Efficiency Internal Combustion Engine Development

The main objective of this work is to describe the design and testing of novel cam profiles, which are key for efficiency demonstration on a new class of internal combustion engine (ICE). A recuperated split cycle engine (RSCE) has unique demands for valve lift, duration and phasing when compared to a conventional 4-stroke. In particular, good control of the expander intake valve opening (IVO) app

Bend

Bend is a Naturum proposal located in Limhamn, Malmö, within a former limestone quarry. A Naturum is a Swedish visitor center designed to engage visitors with a site’s natural, cultural, and geological characteristics. In this project, Bend reinterprets the concept, translating the quarry’s qualities compression, fragility, and structural tension into architectural form. The design seeks to create

High gas-pressure apparatus for nonlinear X-ray propagation and reshaping via stimulated X-ray Raman scattering

We describe an experimental setup for non-linear interaction and propagation of ultrashort and intense x-ray free-electron laser (XFEL) pulses in a dense gas. It allows one to provide high, but adjustable, target-gas pressures of up to 6 bar within a vacuum environment of 3∙10− 3 mbar or better. The setup enables investigation of intense x-ray propagation in an optically thick medium with minimal