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The current framing of AI-driven technologies situates them as solutions to a looming care crisis. However, this overlooks informal caregivers' key role to current State budgetary deficits impacting healthcare services happening in Europe. As States increasingly rely on informal caregivers to provide care before the necessary involvement of healthcare services, there is already well-established re

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis is shaped not only by viral entry mechanisms but also by interactions with host and microbial factors. The viral spike (S) protein can bind Gram-negative bacterial lipopolysaccharide (LPS), a driver of hyperinflammation in severe COVID-19. How viral evolution over the years alters this interaction remains unclear. Here, we i

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One of the most prevailing ideas within contemporary philosophy of language is Representationalism: the idea that there is a word-world relation which plays a key role for explaining how language works. This relation is usually invoked both to explain what our utterances are about – what names and noun-phrases refer to – and what our utterances mean – how they represent the world as being. The top

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The promise that AI tools will relieve teachers of tedious tasks and liberate time for more ‘valuable’ work with students has become a dominant narrative. However, the implementation of automated technologies raises questions around how human labour is implicated and situated in these processes. From the perspective of maintenance and repair studies we approach the often-hidden labour that teacher

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The power systems of drilling rigs have changed considerably since the early days of steam driven machinery. This paper reviews that progression, from mechanical and diesel electric configurations through to modern hybrid and renewable integrated systems, with a focus on the power conversion technologies that enable each stage. Coverage includes the electrical architecture of drilling rig power sy

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This chapter focuses on the impact of the war on the mental well-being ofuniversity students. First, we will provide a brief overview of the “generationof war” – comprising the majority of the current university students – and themental health issues that war can cause. Next, we present the results of astudent well-being survey conducted at Zhytomyr Polytechnic State Uni-versity in 2022, 2023 and

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Importance Longitudinal data are crucial for understanding rapid population aging in East and Southeast Asia, yet challenges in establishing and managing infrastructures remain undocumented.Objective To investigate challenges and adaptations across longitudinal aging datasets in East and Southeast Asia and synthesize stakeholder-informed processes and recommendations to guide future study design

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Background and ObjectivesThe number of older adults living alone is increasing globally, often with varied risks and resilience capacities. Digital technologies may help mitigate these risks, but their potential remains poorly understood. This review maps evidence on digital technologies in social and health care interventions for older adults living alone, focusing on technology types, functions,

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BACKGROUND: Type 2 diabetes mellitus (T2DM) is common among people with HIV (PWH), although studies comparing T2DM-related complications in people with and without HIV (PWoH) remain limited. This was assessed using data from the Cohort Study on Morbidity and HIV in Sweden (COSMOHS).METHOD: Nationwide study including Swedish residents born 1930-2006, diagnosed with T2DM between 2010 and 2019, follo

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Den här broschyren riktar sig till dig som vill veta mer om vad palliativ vård är och vad den kan göra för personer med allvarlig sjukdom eller vid tillstånd då livet är hotat.Palliativ vård fokuserar på livskvalitet och kan starta tidigt i sjukdomsförloppet och pågå parallellt med annan vård. Här får du veta mer om vad palliativ vård är och fördelarna med att påbörja den tidigt, oavsett om det är

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The endothelin receptor antagonist atrasentan improved kidney outcomes in the SONAR trial for type 2 diabetes and chronic kidney disease (NCT01858532), though individual responses varied. To identify molecular biomarkers of atrasentan response and outcome, we conducted a nested case-control proteomics study (N = 180) within the SONAR trial population and identified urinary clusterin (uCLU) as the

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Introduction: Strengthening Primary Health Care (PHC) is essential for building resilient and equitable health systems, but PHC faces barriers in implementation, resource allocation, and political prioritisation. This study aimed to develop a strategic roadmap to enhance PHC by identifying core values, priorities, and actionable strategies through expert consensus. Methods: A two-round Delphi stud

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Globally, a substantial number of children experience various forms of parental maltreatment. Child protection agencies work to support these children and prevent further abuse or neglect, often through targeted interventions directed at the parents. Previous research has indicated that social workers may approach male and female perpetrators of maltreatment differently once a case is reported. To

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BACKGROUND: One key element of lung-protective ventilation is the use of a low tidal volume (VT). A sex difference in use of low tidal volume ventilation (LTVV) has been described in critically ill ICU patients.OBJECTIVES: The aim of this study was to determine whether a sex difference in use of LTVV also exists in operating room patients, and if present what factors drive this difference.DESIGN,