Sökresultat

Background. Seeking to clarify the parent-offspring transmission of Major Depression (MD) and type I Bipolar Disorder (BD), we examined offspring MD and BD risk in five informative parental pairs: Unaffected x MD, Unaffected x BD, MDxMD, MDxBD and BDxBD. Methods. We identified 289,637 individuals born in Sweden 1970-1990, followed through 2018, from parents with MD and/or BD identified from Swedis

Nickel phosphides are promising earth-abundant, low-cost catalysts for hydrogen/oxygen evolution reactions and CO2 reduction. However, their formation mechanisms remain poorly understood and difficult to control. This particularly applies to mechanisms determining phase evolution, crystallinity, and morphology under reactive conditions, factors that critically influence catalytic activity and stab

Standard quantum measurements are projective. However, the full scope of quantum measurements is represented by positive operator-valued measures (POVMs) and many of these break the limitations of projective measurements as resources in quantum information. It is therefore natural to consider how accurately an experimenter with access only to projective measurements and classical processing can si

Animals have evolved multiple sensory systems that can acquire environmental information guiding their behaviour, allowing them to adapt physiological parameters to current conditions. However, over the past century, anthropogenic changes have increasingly made information on environmental conditions less reliable, by introducing novel elements (such as synthetic chemicals or artificial light), by

Bakgrund Inläggning av central venaccess, exempelvis central venkateter (CVK), är en invasiv åtgärd som kräver sterila betingelser för att förhindra introduktionen av mikroorganismer till blodbanan med en ökad risk för kolonisation respektive kateterrelaterad infektion. Med ett strukturerat arbetskoncept kan man uppnå en infektionsincidens nära noll. Flera aspekter är betonade i riktlinjerna, men

Electronics repair is a core component of a circular economy, yet the many social, technical, and financial barriers limit the widespread adoption of repair practices along the value chain. The high complexity of electronics, reinforced by product design choices, and a perpetuating culture of consumption has normalised replacement when a fault occurs. Similarly, a lack of technical knowledge, unce

Bakgrund: Preoperativ anemi är en välkänd riskfaktor för ett sämre kirurgiskt utfall. Hos patienter med flera riskfaktorer för postoperativa komplikationer är anemi den som lätt kan hanteras inom den tillgängliga tidsramen före operationen. I de fall denna hantering inte genomförs är det dock viktigt att förstår dess negativa påverkan jämfört med andra riskfaktorer. Denna studie syftade till att u

The decarbonisation of industry, which is a significant contributor to greenhouse gas emissions, is closely linked to the energy system and its transformation. This study quantifies the impacts of industrial decarbonisation on the European energy system, considering uncertainties in electricity and hydrogen demand and constraints on renewable energy sources (RES) deployment and cross-border infras

Sensitive detection of short nucleic acids is used to identify viral and bacterial diseases, detect biomarkers of cancer, as well as in gene expression studies. Currently available techniques such as PCR, electrochemical detection and SPR are typically costly and often require amplification of the DNA. Here, we demonstrate a sensing system for picomolar detection of short single-stranded DNA by fl

Background The aim of this systematic review and meta-analysis was to examine autoantibody positive individuals and define: (a) the relative risk of rheumatoid arthritis (RA) compared with autoantibody negative individuals and (b) the cumulative incidence of RA over time, in different populations. Methods A systematic literature search was performed in August 2025. Retrospective case control studi

Astrometric observations can, in principle, be used to detect gravitational waves. In this paper, we give a practical overview of the gravitational wave effects which can be expected specifically in small-field astrometric data. Particular emphasis is placed on the differential effect between pairs of sources within a finite field of view. We also present several general findings that are not rest

Animals align their body in relation to different environmental cues, including spontaneous directional responses relative to the geomagnetic field known as magnetic body alignment. The biological significance of this behavior, however, remains undetermined for most taxa. In previous studies, migratory songbirds aligned their body with the cardinal directions of the geomagnetic field and their mig

Scholars have characterized Cambodia as a weak state, strong party governance system in which administrative institutions are subordinated to the ruling Cambodian People’s Party (CPP). This article argues that since 2013 Cambodian governance has taken a significant technocratic turn, as party rule has become increasingly dependent on a stronger and more capable administrative state. It traces a re

District heating networks are an integral part of the energy system in many countries. In future smart energy systems, they are expected to enhance energy flexibility and support the integration of renewable and waste energy sources. An important aspect of these networks is the control of flow rates, which dictates the heat delivered to consumers. This paper concerns the properties of flow rates i

We explore mental health as a potential mechanism to explain the labor market penalty of an early-onset physical disability using administrative data from Sweden. For methodological reasons, we focus on persons with Cerebral Palsy (CP) and use prescriptions for mental health conditions. We examine how much of the differences in labor market outcomes is explained by prescriptions for mental health

Despite recommendations to use oral lipid-lowering therapies (LLT) in secondary prevention of atherosclerotic cardiovascular disease, numerous studies have shown substantial under-utilization. We assessed long-term persistence and dynamics of adherence to oral LLTs in patients after their first ever myocardial infarction (MI) in Sweden. A total of 83,407 patients with a MI (2010–2017) and who were

Non-ordinary states of consciousness (NOC) offer a way to examine how large-scale brain dynamics reorganize as experience changes. We studied a participant able to reliably enter a self-induced NOC state characterized by vivid imagery, altered bodily perception, and a sense of unity. Across 20 fMRI sessions, we measured functional connectivity in four conditions (Baseline, Transition, NOC, and Res

Many different types of insects make seasonal migrations over vast distances, typically from one broad geographical region to another, most often involving a latitudinal change in one direction in spring with a reversal of this direction in autumn. However, a small handful of these species instead migrate from an enormous geographical area to a highly specific destination they have never previousl

The speed at which the number of battery electric vehicles is growing is fueling debates and research on the criticality of battery materials. But rapid growth also enables fast uptake of new cathode chemistries, and electric vehicle batteries show considerable flexibility and material substitutability. Historical scaling of production is more dynamic than recognized in scenarios of future mineral

Heterochromatin is characterized by an inaccessibility to the transcriptional machinery and is associated with the histone mark H3K9me3. However, studying the functional consequences of heterochromatin loss in human cells has been challenging. Here, we used CRISPRi-mediated silencing of the histone methyltransferase SETDB1 to remove H3K9me3 heterochromatin in human neural progenitor cells. Despite