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The speed at which the number of battery electric vehicles is growing is fueling debates and research on the criticality of battery materials. But rapid growth also enables fast uptake of new cathode chemistries, and electric vehicle batteries show considerable flexibility and material substitutability. Historical scaling of production is more dynamic than recognized in scenarios of future mineral
Heterochromatin is characterized by an inaccessibility to the transcriptional machinery and is associated with the histone mark H3K9me3. However, studying the functional consequences of heterochromatin loss in human cells has been challenging. Here, we used CRISPRi-mediated silencing of the histone methyltransferase SETDB1 to remove H3K9me3 heterochromatin in human neural progenitor cells. Despite
BACKGROUND: Early-career researchers (ECRs) play a vital role in scientific progress; however, academic environments and personal characteristics may influence their mental health and capacity to work. This study explored factors associated with mental health among ECRs in dementia research (ECDRs).METHODS: We analyzed data from an international cross-sectional survey of 283 ECDRs using a logistic
Premise: Flower color, a key trait influencing plant–pollinator interactions, may be influenced by abiotic factors such as soil. We investigated association between pollinators, soil characteristics, and flower color variations in Digitalis purpurea across native populations in Sweden and introduced populations in Bolivia. Methods: We measured floral traits, reflectance of petals and nectar-guide
Background: Reuse of sterile textiles could potentially reduce the carbon footprint of operating theatres. The aim of this mixed-methods study is to gain a deeper understanding of the implementation of reusable drapes and gowns across different contexts through applying the Consolidated Framework for Implementation Research (CFIR).Methods: A mixed-methods analysis was performed of cross-sectional
10Be deposition in ice cores is widely used for solar reconstructions, but its interpretation is complicated by volcanic influences. Using the state-of-the-art aerosol-climate model ECHAM6.3-HAM2.3-SALSA2.0: 10Be, we assess the impacts of three major volcanic eruptions: Agung (1963), El Chichón (1982) and Pinatubo (1991). All eruptions enhance stratospheric 10Be sedimentation, increasing atmospher
Thermal performance curves (TPCs) capture how population growth depends on temperature. When temperatures increase, such as during global change, TPCs may evolve to match new environmental temperatures. While previous studies mostly focus on population growth rate TPCs, evolution can also be strongly trait-dependent and require a multi-trait analysis. Here, we empirically tested how TPCs and multi
Transpiration drives up to 40 % of terrestrial precipitation, with forests playing a critical role. This study combines long-term sap flow measurements and surface-based cloud observations to examine how different clouds affect tree transpiration across boreal and temperate European forests. Under specific cloudy conditions, sap flow can exceed clear-sky levels, reflecting distinct radiation effec
Objective: Interstitial lung disease (ILD) can occur in association with antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV-ILD) or as an isolated entity with positive ANCA (ANCA-ILD). However, data on the epidemiology and outcomes of these conditions remain limited. Methods: A European multicenter retrospective study encompassed patients with AAV-ILD or ANCA-ILD. Baseline and s
This study investigates whether incorporating news-based sentiment into the GARCH-MIDAS framework improves volatility forecasts for the OMXS30 in- dex. The sentiment measure is constructed from Swedish business news articles published in Dagens Industri (DI) between 1995 and 2024, using Latent Dirichlet Allocation (LDA) to identify thematic topics and topic-representative articles. The resulting s
INTRODUCTION: Left ventricular (LV) longitudinal function is a prognostic marker of hospitalization and mortality in LV dysfunction. Recently, left atrial (LA) reservoir and conduit strain have also been presented as independent prognostic markers. However, the atria and ventricles are coupled in the fibrous atrioventricular plane (LA-LV coupling). The degree to which the LA strain is affected, or
This study reports the synthesis and characterization of heterogeneous acid catalysts derived from rice husk biochar, modified by sulfonation and Ce(NO3)3·6H2O (cerium (III) nitrate hexahydrate) impregnation, for fatty acid esterification using methyl acetate as a glycerol-free reaction route. The research aims to valorize agricultural residues as renewable and sustainable precursors for solid aci
Introduction.In policy and political debate, media and information literacy (MIL) is increasingly framed as a civic responsibility and a strategic response to the contemporary ‘information crisis’, marked by disinformation and digital insecurity. This positions MIL as essential to democratic resilience and national security but risks excluding individuals who lack the resources or capacities to meIntroductionIn policy and political debate, media and information literacy (MIL) is increasingly framed as a civic responsibility and a strategic response to the contemporary ‘information crisis’, marked by disinformation and digital insecurity. This positions MIL as essential to democratic resilience and national security but risks excluding individuals who lack the resources or capacities to mee
Ordered assemblies of colloidal semiconductor nanocrystals have traditionally been studied for energy transfer and electronic transport arising from wavefunction overlap between neighboring nanocrystals. In this perspective, we instead focus on light-coupled nanocrystal solids engineered primarily for light emission. These materials include ordered superlattices and compositionally doped assemblie
We explore interactions between equally charged surfaces in the presence of simple salt and either neutral or monovalently charged polyampholytes. We consider the possibility of using these charged polymers as crude models of ion clusters. The latter have been hypothesized to form in concentrated aqueous salt solutions and are possibly related to anomalous underscreening. This phenomenon usually m
Using Swedish-matched employer-employee data from 2001 to 2018 and parametric survival analysis, we examine how the share of off-farm wage income affects survival time in the state of hybrid farming. We find a non-linear relationship between the share of off-farm wage income and the risk of exit; at lower levels, the share of off-farm wage income increases the risk of exiting agriculture completel
A number of recent experiments have indicated that magnetic nanoparticles can become locally hotter than their nonmagnetic surroundings during induction heating. While such nanoscale hotspot-effect is particularly attractive for applications within biomedicine and catalysis, its existence is a topic of scientific controversy. To address this, we here present simultaneous measurements of the intern
Mannosyl β-C-1 amidotriazoles have previously been reported to have higher selectivity for galectin-9N (N-terminal domain) than the corresponding galactoside C3 amidotriazoles have, which were more selective for galectin-3. This study further investigated this by synthesis of mono- and bis-aryltriazolyl mannoside analogues to known high-affinity galectin-3 galactosyl-derived inhibitors. Following
