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Rupture of unstable atherosclerotic plaques is a major cause of mortality. Endothelial-to-mesenchymal transition associates with advanced atherosclerotic plaques and contributes to plaque progression. We examined the role of Twist1, a transcription factor that drives endothelial-to-mesenchymal transition, in plaque progression by inducible deletion from endothelial cells in hypercholesterolemic mi

Background The 2023 European Society of Cardiology (ESC) guidelines for acute coronary syndromes (ACS) maintained a Class III recommendation against routine pretreatment with oral P2Y12 inhibitors in non-ST-segment elevation ACS (NSTE-ACS) and downgraded pretreatment in ST-segment elevation myocardial infarction (STEMI) to Class IIb. This study evaluated real-world uptake of these recommendations

Rapid urban growth is making cities hotter, a trend further exacerbated by climate change. Urban green spaces (UGS) are commonly used as nature-based solutions to reduce heat, but there are gaps in understanding how cooling effects vary across climate zones. Using satellite data from 2021 to 2024, we examined urban heat and UGS patterns during the hot season across four Ethiopian cities with diffe

Bone conduction hearing implant systems (BCHIs) are established treatments for patients with conductive or mixed hearing loss or single-sided deafness when conventional hearing aids are unsuitable. This study evaluated the cost-effectiveness of the active transcutaneous system Sentio versus a similar system, i.e., Osia in an Australian setting. Scenario analyses also compared Sentio to other syste

Immersive visual environment can deceive our interoceptive perception of how we move relative to our environment. If the visual environment or a high reliance on vision produces straining work conditions, motion sickness or is associated with a medical disorder, the causes merit addressing. Therefore, the purpose of this study was to investigate whether postural control adapts to challenging visua

This thesis consists of three self-contained papers that examine how information and ideologies serve as coordinating forces during episodes of political and social transformation.The first paper studies how shifts in public sentiment can trigger mass mobilization, using the Finnish Civil War of 1918 as a natural experiment. I show that the abrupt abolition of Russian imperial censorship in 1917 p

Background: Inadequate postoperative pain management after lumbar discectomy may delay recovery, increase the risk of chronic pain, and prolong hospitalization. Effective analgesic strategies must balance pain control with minimal adverse effects. Objective: To identify the most effective postoperative analgesic interventions for patients undergoing lumbar discectomy. Databases and Data Treatment:

Rapid warming in the Arctic is transforming northern ecosystems and altering their role in the global carbon cycle. Rising temperatures are driving shifts in vegetation composition, phenology, and ecosystem functioning, including earlier growing seasons and the expansion of shrubs across tundra landscapes. These changes influence surface energy balance, carbon uptake, and climate feedbacks, yet su

At the turn of the twentieth century, infant- and child mortality declined rapidly in many industrializing societies. In Sweden, this decline coincided with industrialization and urbanization, as well as a period of growing social disparities in childhood mortality. The inequality in child survival was connected to a range of factors, including access to water- and sanitation, housing conditions,

In this episode, the story of Clever Hans, the horse who changed psychology for the better. We also sit down with psychologist and magician Matt Tompkins. Matt is the author of The Spectacle of Illusion, a book about the long history of the manipulation of our own magical thinking and how studying deception, and especially self-deception, can help us better understand perception, memory, belief, a

Dr. Matt Tompkins, experimental psychologist and magician, explores the intersection of magic and cognitive science. From mastering coin tricks as a child to designing "fake mind control machines" at Lund University, Matt reveals how magicians understood principles like change blindness decades before scientists. He discusses his book "The Spectacle of Illusion," founding the Science of Magic Asso