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As the core hub of cellular energy metabolism and signal transduction, the maintenance of mitochondrial functional homeostasis is crucial for cellular fate. This thesis investigates mitochondrial respiratory and redox responses in selected models of mitochondrial stress, with particular attention to cell-typ differences and methodological aspects of PBMC-based mitochondrial respiration. The first

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Ethiopian air pollution is understudied yet highly relevant considering population size and source abundance including solid fuel cooking, small scale waste burning and vehicle fleet. Low cost PM2.5 sensors can be used to mitigate this by mapping pollution exposure. We report on indoor and outdoor measurements with Sensirion sensors SPS30 and SEN55, the former extensively validated in literature,

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This thesis investigates the martensitic phase transformation with the aim of developing predictive models for its formation and evolution under different conditions. The work seeks to provide a fundamental understanding of martensitic transformation through both macroscale continuum modeling and mesoscale crystal plasticity modeling. The continuum modeling considers the austenite to martensite p

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The development of future forest deadwood is uncertain, as processes related to deadwood formation (i.e., tree growth and mortality) as well as deadwood decomposition are simultaneously impacted by climate change. To elucidate future deadwood dynamics under scenarios of climate change, we combined a map of current global deadwood stocks with tree growth and mortality rates simulated by five dynami

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Emergent macroscopic descriptions of matter, such as hydrodynamics, are central to our description of complex physical systems across a wide spectrum of energy scales. The conventional understanding of these many-body phenomena has recently been shaken by a number of experimental findings. Collective behavior of matter has been observed in mesoscopic systems, such as high-energy hadron–hadron coll

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Hybrid desalination processes have gained attention for overcoming limitations of conventional membrane desalination. Forward osmosis (FO) systems using thermo-responsive polymer draw solutions are considered promising. In this work, the feasibility for water recovery from a thermo-responsive block copolymer solution (PAGB2000) was investigated using pervaporation (PV) and nanofiltration (NF) memb

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In response to increasing human pressures on biodiversity, conservation targets have been set to reduce these pressures and halt biodiversity decline. However, consequences of these objectives on common species are rarely studied. We analyse the effect of a range of drivers related to climate, land use and land-use intensity on 265 common bird and 144 common butterfly species from more than 20,000

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In this chapter, we discuss research from behavior, event-related brain potentials, and neural oscillations that suggests that cognitive and neural constraints affect the timing of speech processing and language comprehension. Some of these constraints may even manifest as rhythmic patterns in linguistic behavior. We discuss two types of constraints: First, we review how the unfolding acoustic and

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PurposeStreptococcus pyogenes cause invasive infections with variable incidence over time. In 2023, an increase in invasive S. pyogenes infections caused by emm-types 1 and 12 was reported globally. In Southern Sweden an increase in S. pyogenes emm12 severe infections was also noted and we set out to determine if this increase was caused by a single genetic sublineage.MethodsData on severe S. pyog

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Bloomsburys description: This book examines schools as dynamic social arenas where everyday interactions are shaped by broader institutional conditions. Drawing on sociological theory - particularly Erving Goffman’s interactionism and dramaturgical perspective - Ingrid Bosseldal and Anders Persson analyze how teachers and students perform and negotiate roles within the classroom while also conside

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CVD α-Al2O3 coatings on cemented carbides are widely used in steel turning, where cutting tool performance is strongly dependent on the crystallographic texture of the α-Al2O3 layer. Residual stress, cooling-crack density, and hardness are key factors influencing coating integrity during machining. Although texture has been reported to affect these properties, trends remain inconsistent in the lit

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Background: The knowledge of the long-term consequences of covid-19 is limited. In patients, symptoms such as fatigue, decreased physical, psychological, and cognitive function, and nutritional problems have been reported. How the disease has affected next of kin, as well as staff involved in the care of patients with covid-19, is also largely unknown. The overall aim of this study is therefore th

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Burnishing has shown potential to improve the corrosion, fatigue and wear resistance of stainless steels. In this study, the surface integrity induced by burnishing in AISI 316Ti was characterized using a multi-technique approach based on Electron Channeling Contrast Imaging (ECCI), Electron Backscatter Diffraction (EBSD) and nanoindentation. Slide burnishing with a diamond tool was carried out un

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Dysphagia occurs commonly in the intensive care unit (ICU). Despite the clinical relevance, there is little worldwide research on prevention, assessment, evaluation, and/or treatment of dysphagia for ICU patients. We aimed to gain insight into this international knowledge gap. We conducted a multi-center, international online cross-sectional survey of adult ICUs. Local survey distribution champion

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Kapitlet undersöker hur förståelsen av transnationell adoption i Sverige har förändrats över tid och hur erfarenheter som tidigare fallit utanför den dominerande föreställningsramen successivt har bidragit till att omforma denna. Med utgångspunkt i Erving Goffmans ramanalys, Johan Asplunds teori om tankefigurer och Eviatar Zerubavels kognitiva sociologi analyseras samspelet mellan social praxis, d

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Non-intubated patients with acute respiratory failure due to COVID-19 could benefit from awake proning. Awake proning is an attractive intervention in settings with limited resources, as it comes with no additional costs. However, awake proning remains poorly used probably because of unfamiliarity and uncertainties regarding potential benefits and practical application. To summarize evidence for b