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CRISPR is a simple yet powerful Nobel Prize winning technology that allows sequence specific editing and manipulation of DNA sequences. The CRISPR facility at Lund Stem Cell Center is here to help you with your projects using this technology. What is CRISPR and who is it for? CRISPR started as a “traditional” gene editing tool, where a double stranded DNA break is introduced and repaired by the ce

https://www.stemcellcenter.lu.se/article/lund-crispr-facility-here-help - 2025-11-01

The results are in and it’s time to announce the winners of Lund Stem Cell Center Image Competition 2020. We are pleased to announce the winners of the Lund Stem Cell Center Image competition 2020 are:First place: Grasping at straws – Ludwig Schmiderer and Martin Hjort, Larsson group and NanolundSecond place: Floating – Maciej Ciesla, Bellodi groupThird place: Million dollars worth of antibodies –

https://www.stemcellcenter.lu.se/article/image-competition-2020-results - 2025-11-01

The leadership team set to guide Lund Stem Cell Center for the next three years was announced in early September 2020. In this interview with newly appointed coordinator Johan Jakobsson and deputy coordinator Johan Flygare, we hear about their future plans for this center of research excellence. What have been your first steps since taking over the reins at Lund Stem Cell Center? JJ: We have been

https://www.stemcellcenter.lu.se/article/plans-future-lund-stem-cell-center - 2025-11-01

Despite the ongoing pandemic, researchers from Lund Stem Cell Center are bringing science to schools both physically and using a digital platform. High school students across the Skåne region are learning about stem cell research in the ‘Taking science to schools – Borrow a scientist’ initiative, organized by the Research School in Stem Cell Biology.In this outreach project – planned for spring 20

https://www.stemcellcenter.lu.se/article/taking-stem-cells-high-schools-during-covid-19-pandemic - 2025-11-01

A research group from Lund Stem Cell Center aims to understand a specific type of neuron that could underlie several brain disorders including schizophrenia, epilepsy and autism, and are developing exciting new strategies to treat them. For the brain to function properly, signaling – be it excitatory or inhibitory – must be properly balanced. This is where a nerve cell known as interneurons come i

https://www.stemcellcenter.lu.se/article/restoring-neural-networks-and-understanding-brain-disorders-0 - 2025-11-01

With the enormous pressure on the Swedish health care system during the ongoing pandemic, researchers from Lund Stem Cell Center are helping battle Covid-19. In response to the increasing number of Covid-19 cases in the south of Sweden, researchers from Lund Stem Cell Center have been working at Lund University Hospital over the holiday period and into the new year, supporting Region Skåne. Johann

https://www.stemcellcenter.lu.se/article/researchers-help-fight-against-covid-19 - 2025-11-01

The fight against COVID-19 continues. In Lund, researchers have been awarded a large Vinnova grant to identify a compound that could be used to prevent viral infection, and thus save lives. The project is a co-operation between preclinical, clinical researchers and a company, an efficient way for creating synergies in research. Project Manager for the study is researcher Sinem Tas, Fellow in Darcy

https://www.stemcellcenter.lu.se/article/new-interdisciplinary-co-op-between-researchers-healthcare-and-industry-formed-fight-virus - 2025-11-01

We are very happy to announce that Emma Hammarlund and the Evolution of Stemness Control and Multicellularity research group have joined Lund Stem Cell Center! Emma and her team aim to understand how the rise of animals on Earth relates to the evolution of stemness control, an event we know very little about. Why animals evolved on the Earth remains poorly understood. As does what drove unicellula

https://www.stemcellcenter.lu.se/article/emma-hammarlund-joins-lund-stem-cell-center - 2025-11-01

PhD student Martina De Santis will be defending her thesis titled ‘Next generation bioengineering of lung tissue for transplantation’ on Friday 19th February 2021. In this interview, Martina tells us about her research in the Lung Bioengineering and Regeneration group and time spent at Lund Stem Cell Center. Can you tell us about your research? -Over three million people die each year and over 60

https://www.stemcellcenter.lu.se/article/phd-defence-interview-martina-de-santis - 2025-11-01

Researchers from Lund Stem Cell Center highlight the importance of controlling viral elements that reside in the genome and how their activation during development may contribute to brain disorders later in life. Around 10% of the human genome is composed of DNA sequences originating from viruses that infected our ancestors throughout the millions of years of our evolution. Under normal conditions

https://www.stemcellcenter.lu.se/article/activation-ancient-viruses-during-brain-development-causes-inflammation - 2025-11-01

Researchers from Lund University in Sweden have identified a new layer of gene regulation mediated by changes in ribonucleic acid metabolism downstream of major oncogenes. This study, published now in the Molecular Cell journal, explains aggressive clinical features observed in triple negative breast cancers. A collaborative study between Lund Stem Cell Center (LSCC) and Lund University Cancer Cen

https://www.stemcellcenter.lu.se/article/regulation-rna-splicing-reveals-unique-clinical-features-aggressive-breast-cancers - 2025-11-01

During her PhD studies Shelby Shrigley has been exploring patient-specific cell replacement therapy for Parkinson's disease. Defending her PhD thesis on March 12th, here Shelby tells us about her research within the Developmental and Regenerative Neurobiology research group led by Prof. Malin Parmar and her time spent at Lund Stem Cell Center. Can you tell us about your PhD research? The main focu

https://www.stemcellcenter.lu.se/article/phd-defence-interview-shelby-shrigley - 2025-11-01

In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases. Now, researchers at Lund University in Sweden have developed a new, efficient method based on the genetic scissors CRISPR-Cas9, that facilitates antibody development. The discovery is published in Nature Communications. Antibody drugs are the fastest growing class of drug, and several therapeu

https://www.stemcellcenter.lu.se/article/new-method-developing-antibody-based-drugs - 2025-11-01

The fight against COVID-19 continues. In Lund, researchers are working to identify a compound that could be used to prevent viral infection, and thus save lives. “This model that has been developed with our collaborators will fill an important gap for current and future drug screening efforts for the upper or lower airways using human airway cells”, says Sinem Tas, associate researcher. The most r

https://www.stemcellcenter.lu.se/article/new-model-human-airways-speeds-battle-against-covid-19 - 2025-11-01

Luftföroreningar är en av de främsta orsakerna till sjuklighet och för tidig död över hela världen. I en forskningsstudie från Lunds universitet på uppdrag av miljöförvaltningen i Malmö, gjordes en hälsokonsekvensanalys för att uppskatta hälsoeffekterna av en hypotetisk miljözon i Malmö. Miljözoner, eller lågutsläppszoner, är områden där de mest förorenande fordonen regleras. Vanligtvis innebär de

https://www.medicin.lu.se/artikel/miljozoner-skulle-kunna-radda-liv - 2025-11-01

Mellan 1998 och 2019 ökade andelen vårddygn med infektionsdiagnos i Sverige från 11 till 21 procent. Ökningen har skett i alla åldersgrupper, men är störst hos personer över 80 år. Det visar en studie från Lunds universitet som publicerats i tidskriften The Lancet Regional Public Health. Infektionssjukdomar är en bred sjukdomsgrupp som inkluderar bland annat sepsis, lunginflammation och urinvägsin

https://www.medicin.lu.se/artikel/allt-fler-med-infektionsdiagnos-pa-svenska-sjukhus - 2025-11-01

Efter att Svenska läkaresällskapet beviljat Sara Alkners forskningsansökan och tilldelat projektet 800 000 kronor, får samma projekt nu även sällskapets pris för bästa vetenskapliga ansökan. Sara Alkner är docent i onkologi vid Lunds universitet och specialistläkare vid Strålenheten, Skånes universitetssjukhus. Hon är också ansvarig för den nu prisade studien, ”The T-REX trial: Tailored regional e

https://www.medicin.lu.se/artikel/projekt-om-stralbehandling-av-brostcancer-prisas - 2025-11-01

Tre forskare vid Lunds universitets diabetescentrum får omkring en halv miljon kronor vardera i stipendium av Hjelt Diabetes Foundation. En viktig målsättning med projekten är att utveckla ny kunskap som kan förbättra behandlingen av typ 2-diabetes och komplikationer som kan uppstå av sjukdomen. Ett av projekten använder sig av avancerad teknik för att öka kunskapen om mekanismerna bakom diabetisk

https://www.medicin.lu.se/artikel/nya-forskningsanslag-okad-kunskap-om-diabetes - 2025-11-01

I Sverige har nyckeln för att framgångsrikt införa precisionsmedicin i hälso- och sjukvården varit den botten-upp strategi där akademi och sjukvård har gått samman för att bygga en nationell infrastruktur. Det skriver 42 författare från Clinical Genomics vid SciLifeLab och Genomic Medicine Sweden, GMS, i Nature Medicine. Tillsammans har Clinical Genomics och GMS etablerat en innovativ modell för a

https://www.medicin.lu.se/artikel/framgangsrik-implementering-av-precisionsmedicin-pa-nationell-niva - 2025-11-01

Kungliga vetenskapsakademien, KVA, har valt in två nya ledamöter i akademins klass för medicinska vetenskaper. En av dem är Malin Parmar, professor i cellulär neurovetenskap vid Lunds universitet. Tillsammans med sin forskningsgrupp har hon gjort flera banbrytande studier som stamceller, som lett fram till utveckling av nya behandlingar för patienter med Parkinsons sjukdom. Utifrån kunskap om hur

https://www.medicin.lu.se/artikel/lundaprofessor-invald-i-kungliga-vetenskapsakademien - 2025-11-01