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Low CXCR1 Expression and Susceptibility to Acute Pyelonephritis
Urinary tract infections (UTIs) are clustered in certain individuals but the molecular basis of disease susceptibility is not known. A single gene was shown to control the susceptibility to acute pyelonephritis and renal scarring in mice. The IL-8 receptor homologue (mIL-8Rh) controls neutrophil function during acute infection and the mIL-8Rh deletion causes tissue damage through neutrophil entrap
Let's Wan study : anti-fandom engagement, identity construction and affinity space in China
M(III) Site-Driven Structural Engineering on Lead-Free Layered Double Perovskite Nanocrystals with Enhanced Photoelectrochemical Activity
Over the past decade, organic–inorganic hybrid perovskites have revolutionized next-generation semiconductors, driving unprecedented advancements in cost-effective optoelectronics. While lead-based perovskite semiconductors exhibit exceptional optoelectronic properties, their inherent toxicity and vulnerability to environmental degradation remain significant barriers to widespread commercializ
Potentially toxic metal contamination in semi-arid agricultural soils : sources, risk analysis, and spatial distribution
The increased demand, driven by a growing population and changing dietary habits, has created immense pressure on agroecosystems throughout the globe. In semi-arid areas, this increased pressure has led to excessive use of agrochemicals in agriculture, which poses a threat of potentially toxic metal (PTM) contamination in agricultural soils. PTMs in agricultural soils result in significant environ
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Kapitulation är visdom - inte nederlag!
Capitulation is wisdom - not defeat! The aim of this study has been an attempt to clarify how parents of children with neuropsychiatric disabilities such as autism, Down syndrome and intellectual disability manage to cope in their everyday life despite the high levels of stress and long term strain it involves being a parent and a caretaker of such a child. We focused our study on the family as a
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Nyhetsbrev från Akademikerföreningen Sveriges Ingenjörer vid Siemens Energy AB Kontakt: asi.se@siemens-energy.com Redaktörer: SvE, CH, JH Nr: 01 2023-01-19 Möt en styrelseledamot Jag heter Jonas Hylén och är med i styrelsen sedan 1998. Redan på högskolan var jag engagerad i studentråd och lovade mig själv att aldrig engagera mig fackligt igen! Fick ändra mig eftersom arbetet i styrelsen för ASI ge
Risk factors in newborns for large waist to height ratio at 1, 2 and 3 year follow up
LIVE-sänt mötet om dansk-svensk kultur med CSS partner
LIVE-sänt mötet om dansk-svensk kultur med CSS partner LIVE-sänt mötet om dansk-svensk kultur med CSS partner Published 1 September 2021 CSS samarbetspartner i projektet Fördomsfönster Öresund – Øresundsinstituttet – arrangerar den 8 september ett live-sänt samtal om dansk-svensk kultur i Öresund. Samtalet äger rum mellan kl 16:30-17:30 och sänds från Form/Design Center i Malmö. Klicka här för att
https://www.css.lu.se/article/live-saent-moetet-om-dansk-svensk-kultur-med-css-partner/ - 2026-04-27
Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes
Background. Anti-glomerular basement membrane (anti-GBM) disease often results in end-stage renal failure despite therapy with plasma exchange and immunosuppressive drugs. The newly discovered streptococcal enzymes IgG-degrading enzyme of S.pyogenes (IdeS) and endoglycosidase S (EndoS) act with remarkable specificity on circulating IgG. In this study, we investigate their ability in vivo to preven
Cultured Mast Cells from Patients with Asthma and Controls Respond with Similar Sensitivity to Recombinant Der P2-Induced, IgE-Mediated Activation
The function of cultured mast cells may depend on genetic or environmental influence on the stem cell donor. This study investigates whether asthma or atopy in the donor influenced the growth and sensitivity of mast cells cultured from patients with asthma and healthy controls under identical conditions. Mast cells were cultured from peripheral blood from twelve patients with an objectively confir
Resting-State Electroencephalogram Complexity Is Associated With Oral Ketamine Treatment Response : A Bayesian Analysis of Lempel–Ziv Complexity and Multiscale Entropy
Introduction: Subanesthetic doses of ketamine are a promising novel treatment for suicidality; however, the evidence for predictive biomarkers is sparse. Recently, measures of complexity, including Lempel–Ziv complexity (LZC) and multiscale entropy (MSE), have been implicated in ketamine's therapeutic action. We evaluated electroencephalogram (EEG)-derived LZC and MSE differences between responder
Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform
Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h
Protein Arp and protein H from group A streptococci. Ig binding and dimerization are regulated by temperature
Direct comparison of two extended-half-life recombinant FVIII products : a randomized, crossover pharmacokinetic study in patients with severe hemophilia A
Development and validation of a machine learning-based model to predict isolated post-challenge hyperglycemia in middle-aged and elder adults : Analysis from a multicentric study
Introduction: Due to the high cost and complexity, the oral glucose tolerance test is not adopted as the screening method for identifying diabetes patients, which leads to the misdiagnosis of patients with isolated post-challenge hyperglycemia (IPH), that is., patients with normal fasting plasma glucose (<7.0 mmoL/L) and abnormal 2-h postprandial blood glucose (≥11.1 mmoL/L). We aimed to develop a
A Simulation Study Quantifying the Effects of Drive Cycle Characteristics on the Performance of a Pneumatic Hybrid Bus
In the study presented in this paper, the effect of different vehicle driving cycles on the pneumatic hybrid has been investigated. The pneumatic hybrid powertrain has been modeled in UT-Power and validated against experimental data. The GT-Power engine model has been linked with a MATLAB/simulink vehicle model. The engine in question is a single-cylinder Scania D12 diesel engine, which has been c
The feasibility of using Pareto fronts for comparison of treatment planning systems and delivery techniques
Pareto optimality is a concept that formalises the trade-off between a given set of mutually contradicting objectives. A solution is said to be Pareto optimal when it is not possible to improve one objective without deteriorating at least one of the other. A set of Pareto optimal solutions constitute the Pareto front. The Pareto concept applies well to the inverse planning process, which involves
Towards alkali-stable polymers and hydroxide exchange membranes functionalized with alicyclic quaternary ammonium cations
In the current work, cationic polymers functionalized with N-alicyclic quaternary ammonium (QA) cations were synthesized and characterized as potential hydroxide exchange membranes (HEMs) for application in fuel cells. Three different polymers, namely poly(arylene ether sulfone), spiro-ionene and poly(arylene alkylene), were explored as polymer backbones for the HEMs. Various mono- and spirocyclic
