Filtyp
BACKGROUND: Ageing is associated with circadian rhythm sleep disorders, poor sleep at night, less physical activity and more time spent indoors, affecting the wellbeing of older adults. Their sleep and mood could benefit from daytime outdoor physical activity, exposure to daylight, better indoor lighting and sleep routines. However, changes to routines can be challenging depending on individual be
Context. Near-infrared high-resolution échelle spectrographs unlock access to fundamental properties of exoplanets, from their atmospheric escape and composition to their orbital architecture, which can all be studied simultaneously from transit observations. Aims. We present the first results of the newly commissioned ESO near-infrared spectrograph, Near-InfraRed Planet Searcher (NIRPS), from thr
Background: Five risk factors account for approximately 50% of the global burden of cardiovascular disease. How the presence or absence of classic risk factors affects lifetime estimates of cardiovascular disease and death from any cause remains unclear. Methods: We harmonized individual-level data from 2,078,948 participants across 133 cohorts, 39 countries, and 6 continents. Lifetime risk of car
Context. Ultra-hot Jupiters (UHJs) are gas giant exoplanets that are strongly irradiated by their star, setting intense molecular dissociation that leads to atmospheric chemistry dominated by ions and atoms. These conditions inhibit day-to-night heat redistribution, which results in high temperature contrasts. Phase-curve observations over several passbands offer insights on the thermal structure
INTRODUCTION: Total alloplastic replacement of the temporomandibular joint (TMJ) is a viable treatment option for severe TMJ disorders (TMDs) unresponsive to conservative approaches, as well as for reconstruction of congenital or acquired TMJ defects. However, clinical data on indications, outcomes, complications and long-term effects remain limited, and no global registry currently exists. This s
BackgroundPrimary care is key to early identification and referral of patients with Alzheimer’s disease (AD). Assessing eligibility for new anti-amyloid treatment may guide appropriate referrals and prevent overburdening specialized care. In this study we determined eligibility for anti-amyloid treatment in patients undergoing cognitive evaluation in primary care.MethodPatients were selected from
Importance The clinical utility of the comprehensive laboratory and medical investigations currently recommended for children with pediatric acute-onset neuropsychiatric syndrome (PANS) remains unclear. Notably, comparisons with relevant psychiatric control patients without suspected immunologic pathogenesis are lacking. Objective To evaluate whether currently recommended laboratory investigations
BACKGROUND: Long COVID has emerged as a global health challenge, with increasing evidence of cardiovascular sequelae. Most previous studies have focused on hospitalised cohorts, whereas cardiovascular risk in community-managed long COVID cases remains less explored. We aimed to investigate the incidence of major cardiovascular events in individuals with long COVID compared to those without long CO
Popular Abstract in Swedish Det är en viktig uppgift för samhället att förebygga HIV och STI (sexuellt överförbara infektioner) bland ungdomar. Under de första åren av 1990-talet, när denna studie genomfördes, ökade dessa infektioner på ett oroväckande sätt. Detta gällde särskilt klamydiainfektionerna och nästan 25% av studenterna vid Lunds universitet rapporterade att de hade haft en konstaterad Slowing the incidence of HIV and STI among young people requires that they change their sexual behaviours. There is evidence that community-based interventions that target multiple levels of influence can be effective. In community mobilization different segments and sectors of a population are directly involved in problem identification and in the design and implementation of programs. The proces
NDVI(Normalized Difference Vegetation Index) was introduced in 1974. Despite its limitations, it has been under use for monitoring bio-physical and cultural landscapes from satellite. The present study employed MODIS based NDVI to examine trends of greenness and its link with LULC (land use/land cover) change and rainfall in Addis Ababa and its surrounding (covering 1,217 sq km) over a period of 1
I juni 2022 röstades ett lagförslag igenom i riksdagen vilket resulterade i att det kostnadsbaserade avdraget för resor till och från arbetet (arbetsresor) ändrades om i grunden till att vara en färdmedelsneutral och avståndsbaserad skattereduktion. Innan de nya reglerna hann träda i kraft den 1 januari 2023 ändrade sig riksdagen och röstade i stället igenom ett förstärkt reseavdrag med höjda schaIn June 2022, a bill was passed through Riksdagen which led to the cost-based write off for traveling to and from your employment (work commute) being changed to accommodate non-specific travel methods and distance based tax deduction. Before the new bills had gone into effect starting from the 1st of january 2023, the Riksdag changed their mind and opted to pass a new bill that allowed for higher
Background: The global plant-based food shift puts high pressure on manufacturing capacity at facilities like Oatly's Landskrona site. This environment faces high combinatorial complexity due to growing product variety and sequence-dependent cleaning requirements. Relying on manual, experience-based planning to navigate these rules limits throughput and introduces organisational risk. Purpose
Many Swedish multifamily buildings from the 1960s are now reaching a stage where major renovation is needed to improve energy performance, indoor environmental quality, and long-term climate performance. At the same time, renovation strategies may involve trade-offs between operational energy savings, embodied carbon, thermal comfort, and material circularity. This thesis evaluates energy-efficien
Background and purpose: Routine collection of patient-reported outcome measures (PROMs) may provide valuable real-world data on quality of life (QoL) and treatment tolerability, complementing clinical outcomes. This study evaluated the feasibility of launching a semi-automated, department-wide PROM collection program at a large tertiary radiotherapy centre. Patients and methods: Patients ≥ 18 year
Importance: Adjuvant chemotherapy regimens may be administered after pancreatic resection for adenocarcinoma arising from intraductal papillary mucinous neoplasms (A-IPMNs), although the evidence supporting their use is limited. Objective: To evaluate the survival benefit associated with contemporary adjuvant chemotherapy regimens after resection in A-IPMNs between 2017 and 2023. Design, Setting,
Importance Early-onset colorectal cancer (EOCRC) (diagnosed age <50 years) incidence is increasing globally, in parallel with increased consumption of ultraprocessed foods (UPFs). The role of UPFs in early-onset colorectal neoplasia remains underexplored. Objective To evaluate the association between UPF consumption and risk of EOCRC precursors. Design, Setting, and Participants This prospective c
Background: Selegiline, rasagiline, safinamide, and zonisamide are commonly used with levodopa to manage motor fluctuations in Parkinson’s disease (PD). This study compared the efficacy and safety of these agents as adjuncts to levodopa in Asian PD patients with motor fluctuations. Methods: A Bayesian network meta-analysis (NMA) was conducted. Randomized controlled trials (RCTs) published from dat
Importance: Recent efforts to clarify the structure of the genetic risks for psychiatric disorders have been limited to disorders with large molecular samples. These heterogeneous samples have typically been ascertained from diverse sources and use a widening range of diagnostic approaches including single-item self-reports. Objective: To assess the structure of genetic risk factors for 18 diverse
IMPORTANCE: Life expectancy is a composite health measure reflecting acute and life-course exposures. Identifying conditions behind disparities in life expectancy can guide policy, planning, and financing to battle the most urgent health problems.OBJECTIVE: To examine the contribution of 33 causes of death to life expectancy disparities, highlighting 2 sets of priority conditions-8 infectious and
