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Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants remain inadequately understood. In this study, we report a genome-wide association study of HF and its subtypes in a sample of 1.9 million individuals. A total of 153,174 individual
Volume 3 of the FCC Feasibility Report presents studies related to civil engineering, the development of a project implementation scenario, and environmental and sustainability aspects. The report details the iterative improvements made to the civil engineering concepts since 2018, taking into account subsurface conditions, accelerator and experiment requirements, and territorial considerations. I
Introduction: Person-centred care (PCC) is widely recommended by the World Health Organisation and other leading healthcare organisations. Although individuals with congenital heart disease (CHD) require lifelong follow-up, it remains unclear whether healthcare systems worldwide provide PCC to this population. This study investigated one key component of PCC, autonomy support, using patient-report
Context. Despite the ever-increasing number of known exoplanets, no uncontested detections have been made of their satellites, known as exomoons. Aims. The quest to find exomoons is at the forefront of exoplanetary sciences. Certain space-born instruments are thought to be suitable for this purpose. We show the progress made with the CHaracterising ExOPlanets Satellite (CHEOPS) in this field using
Background The COVID-19 pandemic has underlined the essential role of primary healthcare (PHC) in epidemiological surveillance and public health decision-making. Across Europe, the integration of electronic health records (EHRs) and the sentinel networks have been pivotal in monitoring COVID-19. However, the lack of standardized PHC indicators for COVID-19 hinders the comparability of data among c
Heavy-flavor quarks produced in proton-proton (pp) collisions provide a unique opportunity to investigate the evolution of quark-initiated parton showers from initial hard scatterings to final-state hadrons. By examining jets that contain heavy-flavor hadrons, this study explores the effects of both perturbative and nonperturbative QCD on jet formation and structure. The angular differences betwee
This paper presents a search for physics beyond the Standard Model targeting a heavy resonance visible in the invariant mass of the lepton-jet system. The analysis focuses on final states with a high-energy lepton and jet, and is optimised for the resonant production of leptoquarks — a novel production mode mediated by the lepton content of the proton originating from quantum fluctuations. Four di
Measurements of integrated and differential cross-sections for W±Z production in proton-proton collisions are presented. The data collected by the ATLAS detector at the Large Hadron Collider from 2015 to 2018 at a centre-of-mass energy of s=13 TeV are used, corresponding to an integrated luminosity of 140 fb−1. The W±Z candidate events are reconstructed using leptonic decay modes of the gauge boso
Background and ObjectivesThe number of older adults living alone is increasing globally, often with varied risks and resilience capacities. Digital technologies may help mitigate these risks, but their potential remains poorly understood. This review maps evidence on digital technologies in social and health care interventions for older adults living alone, focusing on technology types, functions,
Climate change is intensifying short-duration rainfall extremes, increasing urban pluvial flood risk across Swedish municipalities. This study develops a novel spatial statistical framework for basement flood risk assessment using Log-Gaussian Cox Process (LGCP) models on metric graphs, applied to 17 years of flood records from Trelleborg, southern Sweden.Unlike conventional approaches that treat
Lakes and ponds are habitats of great human importance as they provide water for domestic, industrial and agricultural use as well as providing food. In spite of their fundamental importance to humans, freshwater systems have been severely affected by a multitude of anthropogenic disturbances, which have led to serious negative effects on the structure and function of these ecosystems. The aim of
Purpose: This thesis analyses and assesses how companies in Germany’s DAX 40 demonstrate their adherence to the UN Sustainable Development Goals. It evaluates whether these disclosures are mainly substantive, indicating proper strategic integration, or symbolic, aimed primarily at enhancing reputation, and compares their reporting quality to previous international research. Methodology: This rese
Industrial activities, mining and waste management have resulted in extensive contamination of soil, surface water and groundwater all over the world. Around the world, there are different methods used to classify contaminated sites into different risk classes. In Sweden, the method for the inventory of contaminated sites (MIFO) is used. Naturvårdsverket developed it in 1999. MIFO is divided into
Quantum entanglement is a fundamental resource for various quantum information applications including quantum computing, cryptography, and teleportation. However, detecting entanglement in practice can be challenging due to noisy measurements and limited control over the systems being studied. Steering, which is a distinct nonlocal property between entanglement and bell nonlocality (the strongest
