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Objective To assess the efficacy of paquinimod, a new immunomodulatory small molecule, in a murine lupus model, and to evaluate its pharmacokinetics and tolerability in systemic lupus erythematosus (SLE) patients at doses predicted to be efficacious and safe and determine the maximum tolerated dose. Methods The efficacy of paquinimod was studied in lupus-prone MRL-lpr/lpr mice and compared with th
Purpose: To validate the Swedish version of the Distress Thermometer (DT) against the Hospital Anxiety and Depression Scale (HADS) for screening of distress and to explore how well DT measures changes of distress during six months in a population of heterogeneous oncology patients. Methods: The DT was translated into Swedish according to the forward- and back-translation procedure. HADS total scor
“Midnight Reflections about our own Northern Ventriloquist's Skills” is articulated in the form of a podcast in a conversational style scripted by longtime collaborators composer and performer. It starts by cartographing the authors’ previous collaborative works until they approach their last project ensemble, Campo Amniótico [CA] (2021), work in which the feedback or Larsen plays a paramount role
Lars Elleström’s impact on intermedial studies is undoubtedly foundational, multifaceted and systematic. However, his medium-centered model of communication may be said to rephrase some arbitrary communication constants, such as the principle of transfer/transmission of cognitive import between source and target and through the media product. These kind of theoretical attachments imply that severaLars Elleström’s impact on intermedial studies is undoubtedly foundational, multifaceted and systematic. However, his medium-centered model of communication may be said to rephrase some arbitrary communication constants, such as the principle of transfer/transmission of cognitive import between source and target and through the media product. These kind of theoretical attachments imply that severa
AIM: To explore nursing students' experiences of what they had learned and gained through participating in simulation-based communication training anchored in person-centred values.BACKGROUND: Person-centredness is a core component of nurses' work and an important part of it is person-centred communication. To promote patients' wellbeing and comfort, nursing students must become prepared during th
This study explores how scientists navigate research topic transitions during their early-career training and examines its impact on the production of novel knowledge. Drawing on survey data of 270 mid-career scientists in life sciences, we investigate their time investment in topics during early career stages (i.e. during PhD and postdoc training) and trace their research output for 15 years afteThis study explores how scientists navigate research topic transitions during their early-career training and examines its impact on the production of novel knowledge. Drawing on survey data of 270 mid-career scientists in life sciences, we investigate their time investment in topics during early career stages (i.e. during PhD and postdoc training) and trace their research output for 15 years afte
Objective: To estimate the probability of vaginal events (diagnosis and/or surgery) following radical cystectomy (RC) and explore possible risk factors in a nationwide population-based observational registry based study. Patients and Methods: Women undergoing RC for urinary bladder cancer in Sweden, from 1 January 1997 to 31 December 2019, were identified within national registries. Women with any
Introduction: Different strategies in prophylaxis for haemophilia among countries may affect long-term outcome. Aim: The aim of this study is to compare joint health in persons with severe haemophilia (PwSH) between Sweden and Greece, based on different approaches on prophylaxis initiation and management. Methods: Data were extracted from the PedNet Registry, which collects patient data prospectiv
Hybrid electric and full electric vehicles have attracted growing attention during the last decade. This is a consequence of several factors, such as growing environmental concerns, increasing oil prices and a strive for oil independency. Hybrid vehicles have proven to have significant potential to improve fuel economy and at the same time enhance the performance of the vehicle. For the hybrid car
A measurement of the mass of the Higgs boson combining the Formula Presented and Formula Presented decay channels is presented. The result is based on Formula Presented of proton-proton collision data collected by the ATLAS detector during LHC run 2 at a center-of-mass energy of 13 TeV combined with the run 1 ATLAS mass measurement, performed at center-of-mass energies of 7 and 8 TeV, yielding a H
OBJECTIVES: To investigate how the co-occurrence of diabetes, hypertension and overweight/obesity is associated with pain following an exercise intervention for knee and hip osteoarthritis (OA).METHODS: Register-based cohort study. We included people from the Swedish Osteoarthritis Register who underwent education and exercise for knee or hip OA. Diabetes and hypertension were defined using medica
SGEL64 - Samhällsgeografi: GIS i urban och regional planering: en introduktion, 7,5 hp 2018-03-20 till 2018-04-24 Datum Dag Tid Typ Moment Grupp Lärare Sal 2018-03-20 Tis 11-13 F Kursintroduktion & Vad och Varför GIS? Alla LS 430 EM Förberedelse lab Alla 17:00 Anmälan till grupp 1 eller 2 Alla L@L 2018-03-21 Ons 9-12 Ö Modul: Introducing ArcGIS & ArcGIS Basics 1 LS 212 13-16 Ö Modul: Introducing A
https://www.keg.lu.se/sites/keg.lu.se/files/sgel64_schema_vt18_vers180104.pdf - 2026-07-17
We analyzed seasonal flu vaccination rates among the Italian population suffering from Chronic Obstructive Pulmonary Disease (COPD) in order to identify socio-demographic and clinical determinants for vaccination. We used data from the survey "Health and health care use in Italy", which interviewed 5,935 persons (age 15 - 102 years) suffering from COPD in the period 2004-2005. For each respondent,
1 HT2017 – VT2018 Kursanalys MSFM21 Medicinsk strålningsfysik - sjukhusfysik MSFM21: Bildbehandling och dess matematiska metoder Katarina Sjögreen Gleisner Undervisningsform och examination Som ett resultat av att en kursvecka lades till HT 16 är den totala kurstiden nu 7 veckor. Föreläsningarna på kursen ligger i huvudsak fördelade över kursens första tre veckor. Dessa varvas med programmeringsöv
https://www.msf.lu.se/sites/msf.lu.se/files/msfm21_medicinsk_stralningsfysik_-_sjukhusfysik_2019-01-17.pdf - 2026-07-17
Popular Abstract in Swedish Sjukdomen ärftlig hjärnblödning med cystatin C-amyloid angiopati (engelsk förkortning, HCCAA) beror på att en ärftlig mutation i genomet förändrar en byggsten (aminosyra) i proteinet cystatin C. Cystatin C-varianten som uppkommer deponeras som olösligt material (amyloid) i blodkärlens väggar och leder till att dessa ofta brister före 40-årsåldern med hjärnblödning som fHereditary cystatin C amyloid angiopathy (HCCAA) is a disorder characterised by multiple strokes in young adults, resulting in paralysis and dementia. The disease is caused by a mutation in the gene coding for the peptidase inhibitor cystatin C. The mutation causes an amino acid substitution Leu68 -> Gln in cystatin C (L68Q cystatin C) which results in deposition of the protein in the blood vessel
In an exploratory investigation of personality patterns, Swedish air force pilots (n = 22) and ground officers (n = 14) were tested with the Creative Functioning Test, the Serial Color Word test, and the Spiral After-Effect Technique. The participants also answered open questions about their work and about creativity related items. Achievement ratings were made by their superior officers. An initi
Background: The St Gallen surrogate molecular subtype definitions classify the oestrogen (ER) positive breast cancer into the luminal A and luminal B subtypes according to proliferation rate and/or expression of human epidermal growth factor receptor 2 (HER2) with differences in prognosis and chemo-responsiveness. Primary tumours and lymph node metastases might represent different malignant clones
Cigarette smoking among asthma patients is associated with worsening symptoms and accelerated decline in lung function. Smoking asthma is also characterized by increased levels of neutrophils and macrophages, and greater small airway remodeling, resulting in increased airflow obstruction and impaired response to corticosteroid therapy. As a result, smokers are typically excluded from asthma random
