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This thesis analyses the compliance of the CCCTB directive proposals with certain aspects of Protocol (No 2) on the Application of the Principles of Subsidiarity and Proportionality. The thesis presents the various CCCTB proposals issued by the European Commission in 2011 and 2016. The analysis focuses on the CCCTB proposals’ compliance with the principles of subsidiarity and proportionality and h
The goal of this research is to use hematopoietic cells as vehicles for targeting transgenic immunomodulators to the inflammatory sites. The work presented was focused on the anti-inflammatory soluble TNF receptor. A transmembrane soluble TNF receptor (sTNFR1) construct was expressed in hematopoietic cell lines. ER export was facilitated by addition of a transmembrane (tm) sequence, and constituti
Sodium stearoyl-2 lactylate (SSL) lipid surfactant molecules specifically bind partially hydrolysed oat proteins in aqueous medium and significantly enhance the dispersion stability of oat cereal preparations. The proposed complexation is composition dependent and a greater understanding of the role of both oat proteins and lipid surfactant in the effect was gained with data from high performance
RATIONALE AND OBJECTIVES: We wanted to improve determination of the glomerular filtration rate (GFR) with plasma clearance techniques because the alternative-renal clearance techniques-may involve inaccurate urine sampling or risk of urinary tract infection when bladder catheterization becomes necessary. Therefore, we compared the renal and plasma clearances of iohexol and chromium-51-ethylenediam
BACKGROUND AND AIMS: Developing care for older people in the last phase of life requires knowledge about the type and extent of care and factors associated with the place of death. The aim of this study was to examine age, living conditions, dependency, care and service among old people during their last year of life, but also their place of death and factors predicting it. METHODS: The sample (n=
It has been shown that the combination of benzylamine or tyramine and low concentrations of vanadate markedly stimulates glucose transport in rat adipocytes by a mechanism that requires semicarbazide-sensitive amine oxidase (SSAO) activity and H(2)O(2) formation. Here we have further analysed the insulin-like effects of the combination of SSAO substrates and vanadate and we have studied the signal
Veldfires occur as seasonal events in South Africa. During veldfires, the relationship between the fire actors and the affected population is important to the crisis communication. In the Dr. Kenneth Kaunda District Municipality there are primarily three fire actors: the fire brigade, the Fire Protection Association (FPA) and Working on Fire (WoF). The aim of the study is to explore the communicat
This project is a study that has described what condition based maintenance is and has examined the possibilities with condition based maintenance on the new A26 submarine. It finishes with a detailed case study of how a condition based maintenance system could look like on the submarine’s diesel engines. Questions that have been answered are; what is condition based maintenance and how does it wo
The determination of elemental abundances plays an important role inunderstanding the atmospheric processes that lead to anomalies inspectra of chemically peculiar stars. Ongoing study of the HgMn star χ Lupi has defined much of the elemental abundance distribution but progress is dependent upon the availability and accuracy of the atomic data. Here we present experimentally determined wavelengths
The aim of this study was to explore differences and similarities in health care students’ attitudes towards working with and communicating with patients about sexual health issues in their future professions. The aim was also to explore whether the students’ gender, age and future professions were influencing factors and whether there was a change in attitude depending on educational levels, gend
The integration of Artificial Intelligence (AI) within product development has emerged as a significant area of research, especially in 2022-2023. However, there is a lack of empirical research on how AI tools are integrated into the product development process, especially within the ideation stage of startups, and what challenges and opportunities arise from this integration. Our thesis explores
Stopping unsafe work is not only a legal but moral necessity for those that perform work in safety critical industries. Stop Work Authority Cards, Interventions, Refusals of Unsafe Work and the Andon Cord have become symbolic and physical abstractions of decentralization – a shifting of authority down to those which perform the dirty and dangerous work. Paradoxically, the manner in which these for
Europeiska kommissions förslag till en ny Dublin IV-förordning lades fram den 4 maj 2016, COM 2016 (270). Med hjälp av detta instrument ska det vara möjligt att fastställa vilken medlemsstat som är ansvarig för att granska en ansökan om internationellt skydd från tredjelandsmedborgare och statslösa personer som underställs Europeiska unionen. Förslagets effektivitet kommer att studeras genom dess
The infraorder Ceratopsia, or horned dinosaurs, within the clade Dinosauria, shows a specific, restrained migratory pattern. Therefore, the classical view presented by Sereno (1999), of a monodirectal migratory event from Asia to North America via the Bering’s Strait has been commonly accepted in its simplicity. Another hypothe-sis presented during the same time by Chinnery (1998) suggests a migra
Several large, international institutes and think tanks, like Varieties of Democracy (V-Dem), International IDEA, and Freedom House, among others, focus on measuring and tracking government regime types and political environments, primarily through measuring democracies. Yet for all of their sophistication and massive datasets, there are misalignments between democracy scores and human rights for
After the Swedish parliamentary election in 2014, votes of no confidence became considerably more frequent; While they used to occur once or twice per decade, after the 2014 election, six votes of no confidence occurred within seven years. The purpose of this study is to explain why this happened. Furthermore, it develops a new theory for explaining by combining two existing theoretical approaches
Bostadsrätt är en av de vanligaste boendeformerna i Sverige. Det finns närmare 30 000 aktiva bostadsrättsföreningar och ungefär en miljon bostadsrätter. Under det senaste decenniet har priserna på bostadsrätter tredubblats och många nybyggnationsprojekt har inletts. Att köpa en bostad är för många en av de viktigaste investeringarna i personens liv, inte bara för att det är en stor ekonomisk affär
