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CONTEXT: The prevalence of obesity among adolescents has increased and we lack effective treatments. OBJECTIVE: To determine if gastric bypass is safe and effective for an unselected cohort of adolescents with morbid obesity in specialized health care. DESIGN, SETTING AND PATIENTS: Intervention study for 81 adolescents (13-18 years) with a body mass index (BMI) range 36-69 kg m(-2) undergoing lapa

Popular Abstract in Swedish Alla levande organismer har DNA, och eftersom DNA är livsnödvändigt måste det repareras om det blir skadat. Ultraviolett (UV) strålning från solen är en av de vanligaste orsakerna till att DNA skadas. De flesta skador på DNA som orsakas av UV-strålning utgörs av cyklobutan-pyrimidindimerer (CPD) eller (6-4)-fotoprodukter. Dessa skador består av två intilliggande baser sAll living organisms have DNA and since DNA is essential to life it must be repaired when damaged. UV radiation is one of the major DNA damaging agents, which photosynthetic organisms cannot avoid. The major UV-induced DNA lesions are cyclobutane pyrimidine dimers (CPDs) and (6-4) photoproducts (6-4PPs) and the main repair pathways of theses lesions involve photolyases and various excision repair

High blood pressure (BP) is associated with cardiovascular morbidity and mortality. Both genetic and environmental factors are implicated in BP homeostatsis and hypertension development. The aims of the present theisis were: (a) to test if ambulatory BP (ABP) is better than office BP (OBP) to capture the heritable part of BP and if BP variability (BPV) measured by ABP monitoring is a heritable tra

Introduction Aniridia (iris more or less missing), is a congenital, dominant, inherited, serious and sight-threatening disease, most often appearing as an isolated eye disorder. It is caused by mutations in the PAX6 gene, the master gene of the development of the eye. Typically, Aniridia causes severe visual impairment. In addition to glare caused by the iris defect, underdevelopment of the macula

Background: Polymorphisms in and around the CTLA-4 gene have previously been associated to TiD and AITD in several populations. One such single nucleotide polymorphism ( SNP), CT60, has been reported to affect the expression level ratio of the soluble ( sCTLA- 4) to full length CTLA- 4 ( flCTLA- 4) isoforms. The aims of our study were to replicate the association previously published by Ueda et al

BACKGROUND: Pulmonary hypertension may result in significant morbidity and mortality after pediatric cardiac surgery. The objective of this study was to determine the incidence and outcome of severe pulmonary hypertension, defined as a ratio of pulmonary to systemic arterial pressure equal to or greater than 1.0, after cardiac surgery in children. METHODS: Data from all children younger than 18 ye

To cite this article: Cai G-H, Hashim JH, Hashim Z, Ali F, Bloom E, Larsson L, Lampa E, Norbäck D. Fungal DNA, allergens, mycotoxins and associations with asthmatic symptoms among pupils in schools from Johor Bahru, Malaysia. Pediatr Allergy Immunol 2011; 22: 290-297. ABSTRACT: While there is a large variation of prevalence of asthma symptoms worldwide, what we do know is that it is on the rise in

Popular Abstract in Swedish Potatis har varit, och är fortfarande ett viktigt baslivsmedel i svensk kosthållning. Det finns många sorter med olika egenskaper vilket bidrar till dess variationsrikedom. Potatisen är en rik källa till stärkelse, kostfibrer samt vitaminer och mineraler, t ex C-vitamin och järn. En invändning mot potatis ur nutritionell synvinkel är att stärkelsen lätt bryts ned av enzDespite decreased consumption potatoes still constitute an important staple in the Swedish diet. An objection to potatoes and potato products from a nutritional point of view is the ease by which the starch is digested and absorbed in the gastrointestinal tract. This results in unfavourably high glycaemic and insulinaemic responses (glycaemic index, GI and insulinaemic index, II, respectively). Su

INTRODUCTION: Branched iliac stent-grafts (bSG) have recently been developed in order to preserve internal iliac artery (IIA) flow in patients with aneurysmal or short common iliac arteries. The aim of this study is to evaluate a single-center experience with bSG for the IIA. METHODS: Twenty-two male patients (70 (IQR 65-79) years old) underwent EVAR with 23 bSG (1 bilateral repair) between Septem

Introduction: No national recommendation for antibiotic prophylaxis for planned caesarean section in Sweden exists. Swedish delivery units have chosen different strategies. Some units routinely administer antibiotic prophylaxis to all women for whom a caesarean section is planned, while other units give prophylactic antibiotics to risk groups only. We took advantage of this “natural experiment” to

Popular science summary: Beavers are back in Denmark The beaver Castor fiber is an animal which used to be common in most places all over Europe. The beaver has also been an important resource for humans, where especially the meat, the thick fur and the castoreum, a secretion that was used by humans in perfume, medicines and food, was wanted. Therefore, hunting by humans has been the main reason

Abstract Title: Employees’ experiences of working remotely from home during the covid-19 pandemic - a mixed method study at Försäkringskassan Author: Lina Dahlberg Supervisor: Jan Mewes, Lund University Sweden Course: SOCM03 Master thesis course, Master of Science in Human Resource Development and Labour Relations, 30 credits. Department of Sociology, spring 2021 Background & aim: The uni

Riksdagen har under hösten 2020 antagit de lagförslag som utarbetats i prop. 2019/20:190 Ekonomiskt arbetsgivarbegrepp – förändrade skatteregler vid tillfälligt arbete i Sverige. Den mest omtalade ändringen avser den s.k. 183-dagarsregeln i SINK och övergången från ett formellt till ett ekonomiskt arbetsgivarbegrepp. I propositionen presenterades det även lagförslag som numera innebär kraftigt ökaThe Swedish parliament adopted during the late autumn of 2020 the law proposals that were suggested by the Swedish government in prop. 2019/20:190 Ekonomiskt arbetsgivarbegrepp – förändrade skatteregler vid tillfälligt arbete i Sverige. The most debated topic has been the changes in the so called 183-day rule in SINK and the transition from a formal to an economic employer approach. In the same bi

How the IGHV upstream sequences look like? The antibody, also called immunoglobulin (lG), can identify and bind specifically to antigens such as bacteria, viruses, and other disease-causing organisms. Its high variety is achieved by the selection and recombination of genes from normal full-length genomic genes. The antibody contains two identical heavy chains and two identical light chains. What

Konstgjord grundvattenbildning är en viktig teknik i vattenhushållningssammanhang och är idag en av de vanligaste och mest utbredda metoderna i världen för att öka vår grundvattenkapacitet. I många länder har den här tekniken använts under lång tid medan den i andra är i framåtskridande. Tekniken har använts i Europa sedan början av 1900-talet och är fortfarande en vanlig metod för grundvattenförsArtificial groundwater recharge is an important technology in water resources management and is nowadays one of the most common and rapidly spread world wide methods for increasing groundwater capacity. In many countries this technique has been employed for a long time, however in the others it is in progress. It has been used in Europe since the early 1900s, and is still a popular method municipa

Objective: This study aimed to evaluate the outcome and predisposing factors related to perioperative bleeding in patients treated with endovascular aneurysm repair (VAR) for ruptured and non-ruptured abdominal aortic aneurysm (AAA). Design: This was a retrospective cohort study. Methods: A total of 525 consecutive patients (73% elective) with AAA underwent EVAR at two vascular centres from 2008 t

OBJECTIVES: Deteriorating ward patients are at increased risk. Electronic automated advisory vital signs monitors may help identify such patients and improve their outcomes. SETTING: A total of 349 beds, in 12 general wards in ten hospitals in the United States, Europe, and Australia. PATIENTS: Cohort of 18,305 patients. DESIGN: Before-and-after controlled trial. INTERVENTION: We deployed

The aim of this study was to achieve realistic levels of two different types of aerosols commonly abundant in indoor environments in an experimental chamber intended for human exposure studies and aerosol characterization. The aerosols chosen were particles from candle lights (in particle number dominated by inorganic water soluble particles) and from ozone-terpene reactions (organic particles). T

Alcohol consumption may be associated with risk of colorectal cancer (CRC), but the epidemiological evidence for an association with specific anatomical subsites, types of alcoholic beverages and current vs. lifetime alcohol intake is inconsistent. Within the European Prospective Investigation into Cancer and Nutrition (EPIC), 478,732 study subjects free of cancer at enrolment between 1992 and 200