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Sponge phase nanoparticles are lipid-based particles with a porous structure, forming pores with sizes up to 13 nm in diameter. These particles have been proposed for drug delivery by loading cargo within the pores, similar to how ionisable nanoparticles are used today. The larger pores could allow for larger cargo to be delivered to cells. Sponge phase nanoparticles, 277 ± 29 nm in diameter, were

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The controlled delivery of micronutrients to soil and plants is essential to increase agricultural yields. However, this is today achieved using fossil fuel-derived plastic carriers, posing environmental risks and contributing to global carbon emissions. In this work, a novel and efficient way to prepare biodegradable zinc-impregnated cellulose acetate beads for use as controlled release fertilize

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Protein therapeutics need to be formulated into an amorphous solid state to be stabilized, and this is efficiently done by spray drying together with a sugar matrix excipient. The characteristics of the produced powder are strongly dependent on process parameters, and therefore, spray drying offers the possibility of advanced particle engineering. In this thesis, trypsin was spray dried as a model

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Coordination of Official Development Assistance (ODA) has been an important topic in debates focused on improving the outcomes of international development. The subject assumes particular importance with the expected increase of ODA flows to support developing countries addressing climate change-related issues. The case of Mozambique is of special relevance due to the heightened consequences of cl

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Neurotrophic factors are candidates for treating epilepsy, but their development has been hampered by difficulties in achieving stable and targeted delivery of efficacious concentrations within the desired brain region. We have developed an encapsulated cell technology that overcomes these obstacles by providing a targeted, continuous, de novo synthesized source of high levels of neurotrophic mole

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This thesis explores the application of European Union competition law — specifically Article 102 TFEU — to the regulatory conduct of dominant sports governing bodies such as UEFA, FIFA, and ISU. As sport has evolved into a major economic sector, the dual role of these organizations as both regulators and commercial actors has raised significant legal questions concerning abuse of dominance and ma

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This chapter examines the relationship between individual and organizational identity in PSFs and the significant but tenuous nature of elite identity in this context. The authors identify four main identity-related issues for management control in PSFs: autonomy/conformity tensions, the client conundrum, ambiguity saturation, and intangibility. They explore three main modes of identity-focused co

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This thesis will present and discuss e-banking of four major banks in Sweden and the provided service quality required maintaining a good relationship to their customers. The thesis is based on interviews with representatives from the four banks and theories from researches within the field. The result from the studies indicate several aspects showing that the interviewed banks have implemented th

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Recent evidence for efficient delivery of macromolecules, such as peptides and nucleic acids, from the cell exterior to the nucleus offers the interesting possibility of developing novel treatments directed at intranuclear targets. The findings should also stimulate the search for physiological ligands that utilize similar transport mechanisms to regulate pathobiological processes. Cytokines, grow