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Self-Assembly in Lipid-Protein Systems : Lung Surfactant, Stratum Corneum and Model Membranes

Den yttersta barriären mellan luften och blodomloppet i våra lungor består av en lipid-protein film. Denna lipid-protein blandning kallas för lungsurfaktant. Filmen bestående av lungsurfaktant stabiliserar alveolerna i våra lungor och gör att vi kan andas utan motstånd. Brist av lungsurfaktant kan orsaka svåra sjukdomar, till exempel hos förtidigt födda barn som ännu inte hunnit bilda tillräckligtThis thesis explores lipid self-assembly and aims to give a broad picture of self-assembly structures in simple and complex lipid-protein systems. The systems studied are lung surfactant, stratum corneum and simple model membranes. The lung surfactant mixture lines the alveolus in our lungs and stabilises the air- tissue interface. The lung surfactant lipid phase behaviour was here investigated wi

CHANGING WIND PROPERTIES IN SOUTH SWEDEN SINCE THE DAYS OF TYCHO BRAHE

Den kände astronomen Tycho Brahe initierade meteorologiska observationer på ön Ven som noterades i endagbok, nästan oavbrutet från oktober 1582 till april 1597. Fastän observationerna huvudsakligen är kvalitativapå grund av dåtida brist på instrument och metoder kan en stor mängd användbar information erhållas fråndagboken beträffande molntäcke, nederbörd, vindhastighet och riktning, temperaturför

Grasping complexity: analysing risk for sustainable development

Popular Abstract in Swedish Hållbar utveckling ställer krav på nya riskanalysmetoder Hållbar utveckling bygger på vår förmåga att fatta beslut i dag som avgör vår morgondag. Det låter enkelt, men är en av mänsklighetens största utmaningar då mycket i vår värld hänger samman och framtiden är full av osäkerheter. Givet att osäkerhet tillåts påverka vår syn på vad framtiden har i sitt sköte, kan dSustainable development relies on our ability to make decisions today that will determine our tomorrow. Given that uncertainty is explicitly allowed to influence our view of what the future holds for us, most ex ante analyses of challenges for sustainable development can be viewed as analysing risk. Many frameworks for analysing risk exist today, but analysing risk for sustainable development enta

Respiratory mechanics during mechanical ventilation in health and in disease

Popular Abstract in Swedish Patienter, som på grund av lungsjukdom eller annan skada på lungorna inte kan andas tillfredsställande, kan behandlas med hjälp av en respirator som ventilerar lungorna. Respiratorbehandling kan tyvärr tillfoga redan sjuka eller skadade lungor ytterligare skador. Sådana skador kan uppkomma vid ventilation av lungorna vid alltför stora volymer och höga tryck som leder tiThe elastic pressure-volume (Pel-V) curve of the respiratory system can be used as a guide for improved ventilator management. It may indicate risks of lung damage associated with collapse or overdistension of lung units. The work described in this thesis was aimed at developing methods for the determination and characterisation of the Pel-V curve under static and dynamic conditions and at a bette

Kompetensportfölj för dokumentation, reflektion och progression

Vad är en kompetensportfölj? En samling arbetsprover som visar upp den egna kompetensen? En elektronisk plattform för dokumentlagring? En övning i reflektion och utveckling? I denna rapport samlas erfarenheter från medarbetare vid Lunds universitet som under perioden 2015–2016 har arbetat med kompetensportföljer – för studenter och lärare. Rapporten redovisar resultat från tre delprojekt: • Utveck

On the Epidemiology of Soft Tissue Sarcoma and Risk of Cancer following Knee prosthesis surgery. Important factors and methodological notes

Den aktuella avhandlingen härrör ur forskningsinsatser inom klinikerna för onkologi och ortopedi vid Universitetssjukhuset i Lund, och behandlar vad som ursprungligen verkade vara två skilda ämnen.Ena ämnet behandlar epidemiologin för mjukdelssarkom hos vuxna (MDS), en grupp av ofta dödliga sjukdomar av okänd orsak, som behandlas av både onkologer och ortopeder. Här har den historiska oförmågan at

Burgers rock creep around axisymmetric tunnels

The present paper deals with the time - dependent rock deformation during tunnelling, and more particularly, its association with the related phenomenon of creep in its viscoelastic form, as well as the numerical evaluation of it. Initially, a brief introduction of these two phenomena is provided. Then, the Burgers' idealized model of rheological rock mass behaviour is presented and analysed, alon

Psychometric evaluation of the Texas revised inventory of grief in a sample of bereaved family caregivers

The Texas Revised Inventory of Grief (TRIG) was developed to measure the intensity of grief after the death of a close person. It consists of two scales: TRIG I (past behaviors) and TRIG II (present feelings). Because of inconsistencies in previous validations, the instrument needs to be further validated, hence the aim of this study was to evaluate the psychometric properties of the TRIG in a sam

Experiences of chain of care and rehabilitation after stroke : a qualitative study of persons discharged to skilled nursing facilities before returning home

OBJECTIVE: To explore how people with stroke, discharged to skilled nursing facilities before returning home, experience the chain of care and rehabilitation.DESIGN: Qualitative, semi-structured interview design.METHODS: Thirteen stroke survivors discharged from a stroke unit to a skilled nursing facility before returning to independent living participated. Semi-structured telephone interviews wer

Strengthening governance in place-based ecosystems : Lund Model for Innovation Ecosystem Portfolio Tracking

The third generation of innovation policy focusing on addressing societal challenges requires collaborative engagement and action across a broad base of stakeholders over time to contribute to ambitious missions and transform societal systems. The strategic governance of such collaborative work in innovation ecosystems requires a collective vision and direction, a shared view on what to do, and a

Patient consultations during SARS-CoV-2 pandemic : a mixed-method cross-sectional study in 16 European countries

INTRODUCTION: Remote consultations help reduce contact between people and prevent cross-contamination. Little is known about the changes in consultation in European rural primary care during the SARS-CoV-2 (COVID-19) pandemic. The purpose of this mixed-methods cross-sectional study was to find out more about the effects of the pandemic on changes in patient consultations in European rural primary

Diagnostic Dosimetry

Diagnostic nuclear medicine, more recently also named functional molecular imaging, deals with medical procedures performed to help diagnose a variety of diseases. The procedures are based on the use of tracer amounts of radioactive material, where a radionuclide is attached to a ligand with specific affinity to a physiological, metabolic, or receptor-specific process. To balance the benefit of a

Care Home and Home Care Staff’s Learning during the COVID-19 Pandemic and Beliefs about Subsequent Changes in the Future : A Survey Study in Sweden, Italy, Germany and the United Kingdom

The aim of this study was to compare perceptions of learning from the COVID-19 pandemic and beliefs in subsequent changes for the future, among care home and home care staff, in four European countries. A 29-item on-line questionnaire was designed in English and later trans-lated into Swedish, Italian, and German on the impact of the pandemic on stress and anxiety. Anon-ymous data from care staff

From Subsistence to Commercial Producers : Processes of State-led Agrarian Change, Land Tenure Dynamics and Social Differentiation among Smallholders in Ghana.

Agricultural commercialization is concerned with improving market-oriented production in expectation of maximizing profit. While previous state policies in Ghana favoured commercialization by medium and large scale cultivators, there exists a new national commitment dubbed the Planting for Food and Jobs Policy that seeks to leverage on the cumulative productive potential of small farmers for susta

Killer Robots - Autonomous Weapons and Their Compliance with IHL

The pursuit of weapons which distance the soldier from the actual battlefield has been going on ever since the transition from the waging of war using short blades, to the waging of war using bow and arrow. Today, that ambition has reached an almost completion with the ever-increasing number of unmanned, remote-controlled vehicles that are rapidly becoming the most common and prominent method of w

Too many calories, too few nutrients? : a systems approach to food and nutrition security in Guatemala

Obesity levels in developing countries are increasing at an alarming rate, while “old” problems such as hunger and undernutrition still persist, creating a paradoxical situation of a double burden of malnutrition. Intertwined with new sustainability challenges such as climate change and land degradation, food, health and sustainability are interconnected in a complex web of relationships, spanning

Effekten av träning för patienter drabbade av stroke på Vibrosphere ®, en balans- och vibrationsplatta - en pilotstudie som belv en fallstudie

Sammanfattning Bakgrund: Stroke är en av de vanligaste folksjukdomarna i Sverige där 27 000 - 35 000 personer drabbas varje år. Stroke är ett samlingsnamn på vaskulära skador i hjärnan, vilka kan vara ischemiska eller till följd av blödning. En vanlig nedsättning hos personer drabbade av stroke är balansproblematik. Balansen är väsentlig för en självständig vardag och påverkar även den drabbades