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Purpose: To what extent active surveillance and deferred treatment for localized risk prostate cancer are used is unclear. We assessed the use of surveillance and of deferred treatment in a population based, nationwide cohort in Sweden. Materials and Methods: In the National Prostate Cancer Register of Sweden, with a 98% coverage vs the compulsory Swedish Cancer Registry, we identified 8,304 incid
Background: In juvenile idiopathic arthritis (JIA), the trend towards early therapeutic intervention and the development of new highly effective treatments have increased the need for sensitive and specific imaging. Numerous studies have demonstrated the important role of MRI and US in adult rheumatology. However, investigations of imaging in JIA are rare, and no previous study has been comparing
In this study doctoral students in psychology and social anthropology/ethnology were interviewed as to their selection of research problem for their Ph.D. thesis. From the perspective of activity theory it is suggested that the research problem can profitably be seen as the object of activity in research. Graduate students’ selection of a research problem was analyzed as a process occurring over t
Background Primary hyperparathyroidism (pHPT) is associated with an increased mortality attributable to cardiovascular disease (CVD), suggested to be alleviated by surgery. The exact mechanism of the beneficial influence of parathyroidectomy on survival is unknown. Furthermore, studies suggest that there is no increased mortality compared to the mortality rate in the general population during rece
Maternal intrauterine enterovirus infection during pregnancy increases the risk for the offspring to develop type 1 diabetes mellitus. Type 1 diabetes mellitus and autoimmune thyroiditits (AIT) are closely linked. A common pathogenetic factor is possible. The objective of this study was to investigate a possible association between maternal enterovirus infection during pregnancy and the developmen
This thesis looked into the protection and occupational development process under the Thai government shelter and the extent to which it has assisted and supported the victims of human trafficking, both Thai and non-Thai, in psychosocial rehabilitation, therapy, and vocational training and development. I used the capability theory and empowerment approach as a framework of analysis to assess quali
With the post-Kyoto climate negotiations underway, global emissions must be cut by 66% by, 2050 according to the IPCC, to prevent further damage to the environment. In order for this emission cut to be possible, all nations have to be a part of these negotiations. The Kyoto Protocol and the UNFCCC is the natural starting point for a new climate regime that must be established. Through a literatur
To deal with the problems resulting from the current unsustainable pattern of resource utilization, the material life cycle of plastics should be extended. Extended producer responsibility (EPR) has been increasingly adopted as a strategy to redirect the material flow, but its contributions to the market development of recycled plastics have not been well researched. Norway is one of the countrie
The role of environmental permits as a driver for environmental improvements has been a topic of debate for a while. Many permitting regulations were designed in the 1970's and have not been updated since then. Consequently, they have acted mostly as a driver for the adoption of pollution control technologies. Some experts now see that appropriately designed and implemented environmental permi
"It´s difficult, there is a big grey zone”. A qualitative study of preschool teachers’ thoughts on the obligation to report There are several professionals in Sweden who are obligated by law to report when they suspect a possible case of a child being maltreated. The aim of this study was to capture preschool teachers’ thoughts on what that obligation means. How does it work in the field? D
Human trafficking consists of a sequence of smaller events taking place over a large span of time and perhaps even over multiple borders. Perpetrators of the crime take people away from their homes and their origins, either through coercion or threat of force, and instead place them in frightful environments where their survival and human dignity is constantly at risk. Legal measures to fight huma
I mars 2019 röstade EU-parlamentet igenom Direktivet om upphovsrätt på den digitala inre marknaden (”DSM-direktivet”) som medför förändringar i ansvarsstrukturen för upphovsrättsliga intrång på nätet. Direktivets kanske mest kontroversiella artikel är art 17 som behandlar ansvar för särskilda internetplattformar, så kallade ”onlineleverantörer av delningstjänster för innehåll” (”onlineleverantörerIn March 2019, the European Parliament adopted the Directive on Copyright in the Digital Single Market ("the DSM Directive") which implies changes in the liability regime of online copyright infringements. Perhaps the most controversial article in the directive is Art 17, which regulates liability on specific internet platforms, so-called "online content-sharing service providers” (
Mobilizing for increased human rights and democratization in authoritarian states comes with great costs and risks. The post-soviet country of Belarus is often referred to as a textbook example of a consolidated authoritarian state. Despite several attempts, Belarusian society has yet to move towards a democratic transition. The incumbent regime seems to adapt to democratic challenges and stepped
ndia ranges among the countries experiencing most water stress in recent years, while being a major virtual water net exporter. The country’s position relative to its water sources exacerbated since its trade liberalization in the early 1990’s, which calls for a future national water crisis. To comprehend India’s water stress, this study aims to examine the country’s agricultural water use at thre
Flexible Polyvinyl chloride (PVC) is a plastic material commonly used in today’s society and a fundamental material for a lot of sectors. It has advantages over other polymers such as energy-efficient production, flame retardancy, durability and cost-effective. The one important component in flexible PVC that gives it is flexible properties is the plasticizer. The most common plasticizers used are
Cell death is an important field of biology that is linked to many other topics in medicine and biology. One of the methods to investigate cell death is through high content screening (HCS) which makes use of robotic microscopy. By this technology, cell death associated organelle membrane permeabilisation and the localisation of certain dyes can be visualised and elucidate a substantial amount of
Alzheimer’s disease is a severe neurodegenerative disease, affecting the life of millions of patients and those who stand close to them. There is an urgent need for new effective medical treatments targeting this disease, as up to now, there is none. GPR3, a highly constitutively active orphan G protein coupled receptor, was found to interact with several different molecules that are known to play
