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RATIONALE: Sepsis-induced acute kidney injury (AKI) is a common condition with high morbidity and mortality. Neutrophil-derived heparin-binding protein (HBP) induces vascular leakage and is a promising biomarker of sepsis-induced organ dysfunction. It remains unknown if HBP is prognostic of AKI in septic shock and if HBP could play a role in the pathophysiology of sepsis-induced AKI.OBJECTIVES: To

Objectives: Irreversible electroporation (IRE) is a new modality for tumor ablation. Electrodes are placed around the tumor, and a pulsed, direct current with a field strength of 2000 V/cm is delivered. The direct current drives cells into apoptosis and cell death without causing significant heating of the tissues, which spares the extracellular matrix and proteins. The purpose of this review was

Successful use of microgels as delivery systems of antimicrobial peptides (AMPs) requires control of factors determining peptide loading and release to/from the microgels as well as of membrane interactions of both microgel particles and released peptides. Addressing these, we here investigate effects of microgel charge density and conformationally induced peptide amphiphilicity on AMP loading and

Objective: The primary objective was to evaluate 6-month outcomes for brief and extensive automated telephony interventions targeting problematic alcohol use, in comparison to an assessment-only control group. The secondary objective was to compare levels of problematic alcohol use (hazardous, harmful or probable dependence), gender and age among study participants from clinical psychiatric and ad

Purpose: Managing focal cartilage injuries in the middle-aged patient poses a challenge. Focal prosthetic inlay resurfacing has been proposed to be a bridge between biologics and conventional joint arthroplasty. Patient selection and accurate implant positioning is crucial to avoid increased contact pressure to the opposite cartilage surface. A customized femoral condyle implant for focal cartilag

The gene for beta-microseminoprotein MSMB has been studied by DNA hybridization and molecular cloning techniques. Comparative analysis of restriction endonuclease digests of the cloned gene and of leukocyte DNA strongly suggested that the gene is present in a single copy in the haploid human genome. By Southern blot analysis of DNA from somatic cell hybrids, the gene was assigned to chromosome 10.

Objective: To examine reliability and validity of the Swedish version of the Self-Efficacy for Rehabilitation (SER) outcome scale. Methods: One-hundred and ninety-eight inpatients (mean age 69 years) who underwent a primary total knee arthroplasty (TKA) due to knee osteoarthritis participated. They responded pre- and postoperatively to the SER outcome scale, and preoperatively to the Hospital Anxi

We report the first discovery since the 1970s of a new extant family (Aenigmatineidae fam.n.) of homoneurous moths, based on the small Aenigmatinea glatzella sp.n. from Kangaroo Island off southern Australia. It exhibits a combination of extraordinary anatomical characters, and, unlike most homoneurous moths, its larva is a conifer-feeder (stem mining in Callitris, Cupressaceae). While the adult's

While the terms soft power, public diplomacy (PD) and nation brands have cemented their place in academic discourse during the early 21st century, the evaluation of these activities has not been given anywhere near the same level of attention. When describing how campaigns are evaluated, scholars tend to make assumptions based on the goals or outputs of an initiative rather than on the basis of re

This paper explores design students’ proposals for a redesign of the interior of a room of silence at the SUS hospital in Malmö. Reflection and existential meaning-making are discussed in relation to the material culture of design, and more specifically in relation to four different themes found among the students’ proposals: nature as common symbolic framework and salutary force; lighting creatin

Body temperature (Tb) is a valuable parameter when assessing the physiological state of animals, but its widespread measurement is often constrained by methods that are invasive or require frequent recapture of animals. Alternatives based on automated remote sensing of peripheral Tb show promise, but little is known about their strengths and limitations. We measured peripheral Tb in great tits Par

Multiblock copoly(arylene ether sulfone)s with different block lengths and ionic contents are tailored for highly stable and proton conducting electrolyte membranes. Two series of fully aromatic copolymers are prepared by coupling reactions between non-sulfonated hydrophobic precursor blocks and highly sulfonated hydrophilic precursor blocks containing either fully disulfonated diarylsulfone or fu

There are various transport phenomena (gas-phase species, heat, and momentum) occurring at different length scales in anode-supported solid oxide fuel cells (SOFCs), which are strongly affected by catalytic surface reactions at active triple-phase boundaries (TPBs) between the void space (for gas), Ni (catalysts for electrons), and YSZ (an electrolyte material for ions). To understand the multisca