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Over the last years, an expanding family of small regulatory RNAs (e.g. microRNAs, siRNAs and piRNAs) was recognized as key players in novel forms of post-transcriptional gene regulation in most eukaryotes. However, the machinery associated with Ago/Dicer-dependent small RNA biogenesis was thought to be either entirely lost or extensively simplified in some unicellular organisms including Trypanos

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The spectrum of laser-generated acoustic phonons in indium antimonide coated with a thin nickel film has been studied using time-resolved x-ray diffraction. Strain pulses that can be considered to be built up from coherent phonons were generated in the nickel film by absorption of short laser pulses. Acoustic reflections at the Ni-InSb interface leads to interference that strongly modifies the res

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The addition of polypropylene (PP) fibres has been shown to reduce the fire spalling propensity of concrete. When including this type of fibres in the concrete, the concrete mix becomes less robust, and small deviations in the constitutes change the workability and properties of the concrete. So, from a manufacturing perspective as small dosages as possible of PP fibres are desirable. Very few lar

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Under de senaste åren har Patent- och marknadsöverdomstolen hanterat flertalet mål där käranden har stämt svaranden på skadestånd för upphovsrättsintrång efter att svaranden i en tidigare rättegång lämnat in bevisning till vilken käranden äger upphovsrätt. En sådan prövning innefattar en konflikt mellan rätten till rättvis rättegång och äganderätten till upphovsrättsliga verk. Eftersom verket i ocDuring the last couple of years, the Patent and Market Court of Appeal (“PMCA”) have handled multiple cases where the plaintiff has sued the defendant for damages for copyright infringement after the defendant in a previous trial has submitted evidence to which the plaintiff have copyright. Such a trial involves a conflict between the right to fair trial and the right of possession of copyrighted

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År 2025 fick en särskild utredare i uppdrag att analysera hur barnets ställning och stödet till barn i vårdnadsmål kan stärkas. Genom uppsatsens undersökning och analys av den historiska utvecklingen av barns delaktighet i vårdnadstvister under de senaste 100 åren framkommer att det är långt ifrån första gången som denna fråga utreds. Frågan har nämligen utretts ett flertal gånger i statliga offenIn 2025, a special investigator was commissioned to analyze how the position of the child and the support for children in custody cases can be strengthened. Through the thesis’s investigation and analysis of the historical development of children´s participation in custody disputes over the past 100 years, it emerges that this is far from the first time this question has been examined. The issue h

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In this time of global health interventions, preventing borderless diseases, such as Ebola, is a question of implementing global health policies in different cultural contexts. Although these interventions are mediated by international organs, the healthcare workers on the ground are actually those who implement policies. From this starting point, this thesis investigates the extent to which Swedi

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Dispositionsprincipen inom avtalsrätten ger som huvudregel var och en rätt att fritt bestämma över avtalsfrågor så som om avtal ska ingås, vem avtalet ska ingås med och vad avtalet ska innehålla. Inom den rätten ligger även att avgöra hur en framtida tvist dem emellan ska lösas. Avtalsfriheten är dock inte absolut. Den begränsas av ett olika hänsynstaganden, skapade som skyddsregler för svaga partThe principle of freedom of contract gives, as a rule, everyone the right to freely decide over contract issues such as, that agreements are to be concluded, whom the contract is to be concluded with, and what the contract should contain. Within the principle is also to determine how a future dispute between them will be resolved. Contractual freedom is not absolute. It is limited by a variety of

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Code review is a well-established and valuable software development practice associated with code quality, interpersonal, and team benefits. However, it is also time-consuming, with developers spending 10–20% of their working time doing code reviews. With recent advances in AI capabilities, there are more and more initiatives aimed at fully automating code reviews to save time and streamline softw

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Negative symptoms (avolition, anhedonia, asociality, blunted affect, and alogia) are among the most disabling features of schizophrenia spectrum disorders. In the absence of treatment consensus guidelines, this PRISMA-compliant meta-analysis (PROSPERO: CRD42024613967) evaluated efficacy and clinical significance of interventions targeting this dimension. Web of Science/PsycInfo databases were sear

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Massive MIMO has been shown to greatly improve spectral and transmit-energy efficiency. When implementing a massive MIMO system, one challenge is high hardware complexity. A solution is to reduce the number of radio frequency (RF) transceiver chains by performing antenna selection. However, a full RF switch that connects the antennas and RF chains can be highly complex and incurs significant loss

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BACKGROUND: Infants born after IVF are often twins, and singleton IVF babies have an increased risk for preterm birth. Both conditions are likely to increase morbidity. We examined the frequency and duration of hospitalization required by babies born after IVF, and compared this information with all infants born in Sweden during the same time period. METHODS: We used a nationwide registration of I

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Objectives Exposure to diisocyanates is a well known occupational hazard. The objective of this study was to determine the possibility of an association between low exposure to toluene diisocyanate (TDI) (airborne isocyanates and biomarkers of isocyanates in plasma and urine) and symptoms of the eyes and upper and lower airways. Methods Altogether 136 workers occupationally exposed to TDI and 118

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A two-phase hollow-fiber (HF) liquid-phase microextraction (LPME) method was developed for determination of a quaternary ammonium compound surfactant, dicocodimethylammonium chloride, in aqueous samples. The porous HF was fixed on a metal rod support and was impregnated with approximately 6.6 mu L of organic extractant, which was immobilized in the HF pores. Surfactant extraction was facilitated b

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The maldigestion and malabsorption of fat in infants fed milk formula results due to the minimal production of pancreatic lipase. Thus, to investigate lipid digestion and absorption and mimic the situation in newborns, a young porcine exocrine pancreatic insufficient (EPI) model was adapted and validated in the present study. A total of thirteen EPI pigs, aged 8 weeks old, were randomised into thr

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We report on the synthesis and characterization of fluorescent halogen substituted anthracene-bridge-aniline (ABA) supermolecules that undergo structural reorganization on photoexcitation to form transient complexes. The syntheses were achieved in high yields on a large scale and the molecular structures were confirmed by single crystal X-ray diffraction. The photophysics of the ABA supermolecules

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Homeodomain-interacting protein kinase 2 (Hipk2) has previously been implicated in the control of several transcription factors involved in embryonic development, apoptosis, cell proliferation, and tumor development, but very little is understood about the exact mechanisms through which Hipk2 influences these processes. Analysis of gene expression in normal tissues from genetically heterogeneous m