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Grundämnena molybden, wolfram och vanadin spelar viktiga roller i biologiska system. De återfinns bl a i ett antal enzymer, där de genomför s k syreöverföringsreaktioner, d v s de tar en syreatom från en molekyl och överför den till en annan molekyl. Sådana reaktioner är av stor vikt i kemi, eftersom införandet av syre i olika molekyler är viktig vid framställning av många kemikalier som kan använA series of new dioxomolybdenum(VI) and -tungsten(VI) complexes of tripodal tetradentate and tridentate amino bis- and monophenolate ligands have been synthesized and characterized. The majority of the complexes are mononuclear, but dimeric and trimeric oxo-bridged M(VI) (M = Mo, W) were also obtained. The reactivities of all complexes have been investigated in oxygen atom transfer (OAT) processes

Background: Observational studies suggest an inequitable prescription of biologics in psoriasis care, which may be attributed to geographical differences in treatment access. Sweden regularly ranks high in international comparisons of equitable healthcare, and is, in connection with established national registries, an ideal country to investigate potential inequitable access. Objective: The aim wa

Aim: To estimate the effects of targeted elimination of environmental barriers (EB) in the ordinary housing stock in Sweden, and to explore the estimated effects on accessibility at a population level in relation to (a) residents with different functional profiles, (b) different housing types and (c) building periods. Method: Data on dwellings from existing Swedish research databases were utilized

Variants in HNF1A encoding hepatocyte nuclear factor 1a (HNF-1A) are associated with maturity-onset diabetes of the young form 3 (MODY 3) and type 2 diabetes. We investigated whether functional classification of HNF1A rare coding variants can inform models of diabetes risk prediction in the general population by analyzing the effect of 27 HNF1A variants identified in well-phenotyped populations (n

PURPOSE: To develop and assess a technique for self-gated fetal cardiac cine magnetic resonance imaging (MRI) using tiny golden angle radial sampling combined with iGRASP (iterative Golden-angle RAdial Sparse Parallel) for accelerated acquisition based on parallel imaging and compressed sensing.MATERIALS AND METHODS: Fetal cardiac data were acquired from five volunteers in gestational week 29-37 a

Although they are often subjected to critical scrutiny, formal geopolitical practices have rarely been put on trial. One exception is the case of Gudmund Hatt (1884-1960), professor of human geography at Copenhagen University from 1929 to 1947, who was found guilty of “dishonorable national conduct” for his geopolitics during the German occupation. As a contribution to the critical history of geop

Background and purpose — The proximal femur locking compression plate (PF-LCP) is a new concept in the treatment of hip fractures. When releasing new implants onto the market, biomechanical studies are conducted to evaluate performance of the implant. We investigated the relation between biomechanical and clinical studies on PF-LCP. Methods — A systematic literature search of relevant biomechanica

PURPOSE: To present Swedish Macula Register (SMR) data regarding treatment of neovascular age-related macular degeneration (AMD) in clinical practice since 2008.METHODS: A retrospective register-based study was conducted. Evaluation of baseline demographics, visual outcome and number of injections during this period is presented.RESULTS: Mean age at diagnosis was 79 ± (SD) 8 years; 65% were female

Background: To date, the estimated radiation-absorbed dose to organs and tissues in patients undergoing diagnostic examinations in nuclear medicine is derived via calculations based on models of the human body and the biokinetic behaviour of the radiopharmaceutical. An internal dosimetry computer program, IDAC-Dose2.1, was developed based on the International Commission on Radiological Protection

This article aims to contextualise the development of the Code of Ethics for Professional Accountants by the International Federation of Accountants (IFAC) between 1977 and 2006. Drawing on transnational regulation literature, an extensive review of archival documents was conducted. The analysis unfolds the development of the Code in an increasingly complex regulatory environment, revealing the dy

In the last decade, museums that were established in the 20th century by immigrants from the five Nordic countries have become increasingly concerned with broadening their audiences and more actively engaging their visitors. Efforts to do this have varied from offering traveling exhibitions produced in the Nordic countries, film programs, festivals, concert series, cocktail hours, culinary confere

The sparse number of high-resolution human membrane protein structures severely restricts our comprehension of molecular physiology and ability to exploit rational drug design. In the search for a standardized, cheap and easily handled human membrane protein production platform, we thoroughly investigated the capacity of S. cerevisiae to deliver high yields of prime quality human AQPs, focusing on

Objectives: The behavioural experience method has been extensively used in the literature for the measurement of potential bullying behaviours at work. However, this approach presents limitations when used to classify respondents as targets or non-targets of workplace bullying. Therefore, the present study aimed to: (i) identify optimal cut-off points, reflecting a possible subjectively experience

Background: Recent randomized trials demonstrated that laparoscopic lavage compared with resection for Hinchey III perforated diverticulitis was associated with similar mortality, less stoma formation but a higher rate of early reintervention. The aim of this study was to compare 1-year outcomes in patients who participated in the randomized Scandinavian Diverticulitis (SCANDIV) trial. Methods: Be

This work presents the development of a two-moment cloud microphysics scheme within version 5 of the NASA Goddard Earth Observing System (GEOS-5). The scheme includes the implementation of a comprehensive stratiform microphysics module, a new cloud coverage scheme that allows ice supersaturation, and a new microphysics module embedded within the moist convection parameterization of GEOS-5. Compreh

AbstractSeattle is currently the fastest growing city in the United States attracting a large pool of young international professionals – many of whom are working in the IT industry. However, Seattle is also home to a large Nordic community, immigrants once attracted by the agricultural, forestry, and fishing industries. At present however, the city is pulling in a highly educated young Nordic pop

The randomised phase III clinical trial Checkmate-214 showed a survival superiority for the combination of ipilimumab and nivolumab when compared with the previous standard of care in first-line metastatic/advanced clear cell renal cell carcinoma (RCC) (Escudier B, Tannir NM, McDermott DF, et al. CheckMate 214: efficacy and safety of nivolumab plus ipilimumab vs sunitinib for treatment-naïve advan

PurposeIn early breast cancer (BC), five conventional biomarkers—estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor 2 (HER2), Ki67, and Nottingham histologic grade (NHG)—are used to determine prognosis and treatment. We aimed to develop classifiers for these biomarkers that were based on tumor mRNA sequencing (RNA-seq), compare classification performance, a