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Background: Podocalyxin-like 1 (PODXL) is a cell-adhesion glycoprotein and stem cell marker that has been associated with an aggressive tumour phenotype and adverse outcome in several cancer types. We recently demonstrated that overexpression of PODXL is an independent factor of poor prognosis in colorectal cancer (CRC). The aim of this study was to validate these results in two additional indepen
This thesis describes how software for automated bidding on for example auction sites could function. The thesis is divided into three parts. The elements are composed of: • Collecting bid data from the website that the auction is held on and pass the raw data to the main application for further processing. • A graphical presentation of the auction data is shown divided into individual auctions in
Poland, the Czech Republic, and Slovakia all joined the European Union in 2004. Since then, there have been very different trends apparent in all these countries in terms of attitudes to Europe, both at elite and mass level. This thesis examines the nature and level of Euroscepticism in these countries, and discovers a number of reasons for the differences in these trends from country to country.
How is the identity of Swedish diplomats affected by living a very international life, regularly moving from one place to another, while their main task is to represent Sweden at all times? How does the national identity relate to the professional and the international identity and what role does the context play in this process? These are the questions asked in this thesis. By interviewing 39 Swe
Homelessness has always been and will always be a problem in every society. How should we organize the work and care for these people? There are three different types of welfare states, the liberal, the conservative and the social democratic. In the liberal welfare state the market is the supplier of the public good. In the conservative state the family and church and in the social democratic the
Rendering and simulating an ocean as realistic as possible is a desirable effect to many outdoor scenes of movies and video games. The difficulties with simulating a plausible ocean arise from the complex behavior and scaling of the ocean waves. The length of the waves may vary from being just a few millimeters up to several kilo meters long and the waves can for instance break and line up with th
Natural light brings a sense of presence to the physical environment. The interaction between natural light and form puts us in connection with place in a way that can not be simulated or replaced with artificial light. This relationship has fascinated and engaged architects of all times, you could claim that the question of light and form lies at the core of architecture. It is hard to work with
In myoelectric prosthesis design, there is often a trade-off between control robustness and range of executable movements. As a low movement error rate is necessary in any real application, this often results in a quite severe limitation on the dexterity of the user. One possible remedy for this could come from the use of multi-label machine learning methods, where complex hand movements can be ex
This thesis will explore the role of cryptocurrencies in a market index portfolio. The portfolios of a mix of Bitcoin, Ether and the market indices S&P 500, OMXS30 and VTI will be examined and optimized to maximize the Sharpe ratio. This process is done using the Markowitz Portfolio Theory for portfolios containing one market index and either one or both cryptocurrencies, numerically optimizin
I dagens samhälle är innovation av tilltagande värde för såväl industrialiserade som utvecklingsländer och ett innovativt samhällsklimat innebär ett betydande bidrag till den ekonomiska tillväxten och till samhällsutvecklingen i stort. Det bokförda värdet hos dagens bolag består till en stor och växande del av immateriella tillgångar och det blir ständigt lättare att tillgå mer och bättre kunskap.In today’s society innovation is increasingly important for a developed, as well as a developing, country and it is a significant contributor to economic growth and the evolution of society. The accounted value of companies increasingly consists of immaterial property and our access to existing knowledge is ever greater and ever easier. Since ideas and innovations are of such great importance to m
Unmanned stores are increasing in popularity as the prominence of digitalization is changing not only the customer-retailer interface but also the servicescapes of the stores. The current stakeholders within the industry are (1) tech-positive entrepreneurs that want to innovate the industry or (2) convenience-focused retailers adopting technological solutions to ease the workload. These innovation
Recent progress in parameterization of linear robust controllers has made it possible to investigate advanced controller specifications numerically using convex optimization. The main focus of this thesis project is to investigate how to design a LTI controller for a LTI plant using convex optimization, particularly Linear Programming technique. The concerned performance specification is defined a
In this paper, we present a comparison between the reduced mechanisms obtained through a computational singular perturbation method (CSP) and the reduced mechanisms obtained through a lifetime analysis based only on the diagonal elements of the Jacobian matrix and a species sensitivity The two methods are used for the analysis of autoignition, which is an interesting test situation because of the
The reduction of the surface oxide on Rh(111) by H-2 was observed in situ by scanning tunneling microscopy (STM) and high-resolution core level spectroscopy (HRCLS). At room temperature, H-2 does not adsorb on the oxide, only in reduced areas. Reduction starts in very few sites, almost exclusively in stepped areas. One can also initiate the reduction process by deliberately creating defects with t
The present work aims to study preparation of thin MIP films on a gold-coated QCM resonator in a well-controlled and reproducible manner. A surface-bound photo-radical initiator was used to furnish an imprinting polymerization in a dilute solution of template, functional monomer and crosslinker. Prior to polymerization, the photo-initiator was covalently coupled to a self-assembled monolayer of ca
The aim of this study was to investigate if it is possible to dry concrete samples in a microwave aven without damaging the concrete. This method could, if it is possible, fadilitate the work in many laboratories today. In the beginning of the work a theoretical study over the behavior of the microwaves is done. Same different areas in the construction business where it is possible to use microwav
