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A mathematical model, based on branching processes, is proposed to interpret BrdUrd DNA FCM-derived data. Our main interest is in determining the distribution of the G2 phase duration. Two different model classes involving different assumptions on the distribution of the G2 phase duration are considered. Different assumptions of the G2 phase duration result in very similar distributions of the S p
OBJECTIVE—This study, one of the first to address issues of pulmonary insulin delivery in smokers, compared pharmacokinetics of inhaled insulin delivered via the AERx insulin Diabetes Management System (iDMS) in nondiabetic cigarette smokers and nonsmokers. RESEARCH DESIGN AND METHODS—In this randomized two-period crossover efficacy and safety trial in 27 nondiabetic smokers and 16 nonsmokers (18
In the process of evaluating a parallel twin-turbine pulseturbocharged concept, the results considering the turbine operation clearly pointed towards an axial type of turbine. The radial turbine design first analyzed was seen to suffer from suboptimum values of flow coefficient, stage loading and blade-speed-ratio. Modifying the radial turbine by both assessing the influence of "trim" and inlet ti
Skogen är bäst på bild is an electroacoustic text-sound-composition work; it could also be considered a radiophonic work. This was the first work of text-sound composition I ever made, repurposing that more abstract genre here as a direct tool for finding memory and identity in the city. Although Stockholm’s history of text-ljud-komposition (text-sound-composition) is something I have engaged with
Background: Intraventricular hemorrhage causes significant lifelong mortality and morbidity, especially in preterm born infants. Progress in finding an effective therapy is stymied by a lack of preterm animal models with long-term follow-up. This study addresses this unmet need, using an established model of preterm rabbit IVH and analyzing outcomes out to 1 month of age. Methods: Rabbit pups were
This study focuses on the production of subject–verb (SV) agreement in number in L2 French and investigates the role of cross-linguistic influence (CLI) in this particular morphosyntactic domain. CLI is a well-known phenomenon in Second Language Acquisition (SLA) research but it has rarely been investigated systematically in relation to SV agreement in French. The participants of the study are 114
A common challenge in the development of new drug substances is poor dissolution characteristics caused by low aqueous solubility. In this study, microcrystals with optimized physicochemical properties were prepared by precipitation in the presence of excipients, which adsorbed to the particle surface and altered particle size, morphology, and dissolution rate. The poorly water-soluble drug sirame
Boreal and temperate forests are undergoing structural, compositional and functional changes in response to increasing temperatures, changes in precipitation, and rising CO2, but the extent of the changes in forests will also depend on current and future forest management. This study utilized the dynamic vegetation model LPJ-GUESS enabled with forest management (version 4.1.2, rev11016) to simulat
The term “ethical consumption cap” describes all the forces that dampen or delimit a con- sumer’s attempts to consume ethically. It replaces the popular concept of the ethical consumption “gap’” sometimes also called the attitude–behaviour gap because it describes all the reasons that explain why consumers’ not-so-ethical behaviours do not always align with their highly ethical attitudes. The meta
Extensive research is being conducted on magnesium (Mg) alloys for bone implant manufacturing, due to their biocompatibility, biodegradability and mechanical properties. Gadolinium (Gd) is among the most promising alloying elements for property control in Mg alloy implants; however, its toxicity is controversial. Investigating Gd behavior during implant corrosion is thus of utmost importance. In t
Under de senaste åren har det skett en förskjutning i forskningen från att försöka förstå vem som löper risk att bli radikaliserad, till att undersöka vad som gör att vissa individer har större benägenhet att bli radikaliserad. Känslor av exkludering, diskriminering och marginalisering har tidigare kopplats till extremistiska handlingar. Trots det finns det få empiriska studier som utforskar sambaThe present thesis aims to examine the causal role of social exclusion within theradicalization process and further to explore moderating and mediating factors. In recent years there has been a move away from trying to understand who is at risk of becoming an extremist, to exploring what makes someone at risk. Feelings of exclusion, discrimination and marginalization have all been linked to partic
På Galgbackens vattenanläggning i Hässleholm tillämpas bassängsinfiltration genom återinfiltration av grundvatten i en isälvsavlagring. Syftet är att kunna leverera dricksvatten med god kvalitet till konsumenterna. Grundvattnet tas från brunnar i Ignaberga och Tyringe och återinfiltreras i isälvsavlagringen. Syftet med detta examenstarbete är att genom en spårämnesstudie undersöka uppehållstid ochGalgbacken water plant in Hässleholm is applying basin infiltration by re- infiltrating groundwater into a glaciofluvial deposit. The purpose is to supply drinking water with good quality to the consumers. Groundwater is pumped from wells in Ignaberga and Tyringe and re- infiltrated into the glaciofluvial deposit. The aim with this thesis is to examine retention and dispersion of the re- infiltrat
Uppsatsen handlar om hur den svenska lagstiftningen påverkades av den nationalsocialistiska utvecklingen som skedde i Tyskland under åren 1920 – 1945. Den antar ett historiskt utvecklingsperspektiv och är uppdelad i två delar. Den första delen ger en allmän bakgrund samt pekar på de nazistiska rösterna i den svenska politiken vid den aktuella perioden och definierar begreppet nazism. Den andra delThis essay is about how the Swedish legislation was influenced by the development of the National Socialism in Germany during the years 1920 – 1945. The essay will take on a historical development perspective and is divided into two parts. The first part gives a general background and highlights the Nazi voices in the Swedish politics at this current period and defines the concept of Nazism. The s
Parisavtalet, världens största samarbete för en bättre miljö, faktum är att det är världens största samarbete någonsin över precis alla områden. Av den här anledningen handlar den är uppsatsen om just det här avtalet, som har hyllats som tidernas största diplomatiska framgång. Avhandlingen går ut på att jämföra de initiativ som Parisavtalet har lagt fram med ett par väl utvalda ekonomiska teorier Paris agreement, the worlds biggest collective effort for a better climate, in fact it is the worlds largest collaboration between countries ever over all areas of expertice. For that reason is this essay about the agreement, that has been hailed as the greatest diplomatic achievment of all times. The thesis is about comparing the initiative that the Paris agreement has put forth with some economi
Under projektets gång användes gen-editeringsmetoden CRISPR/Cas9 för att förhindra uttrycket av en gen som är associerad med en familjär form av ALS i två stamcellslinjer som hade blivit differentierade till hjärnceller. Genom genuttrycksanalys visades att CRISPR/Cas9 hade lyckats orsaka en fyrfaldig minskning av SOD1-uttryck i båda cellinjer. Amyotrofisk lateralskleros, förkortat ALS är en neuromAmyotrophic lateral sclerosis (ALS) is a neuromuscular disease characterized by the degeneration and death of both upper and lower motor neurons for which there is no cure currently available. The degeneration of motor neurons leads to the inability to carry out voluntary movement and death usually occurs 3-5 years after disease onset by respiratory failure. The most common cause of familial ALS i
Godssektorn spås bli en tidig användare av självkörande fordonsteknik. Minskade drivmedelskostnader, ökad flexibilitet i ruttplaneringen och utökade drifttider är exempel på incitament för godsföretag att ställa om till en självkörande lastbilsflotta. Automatiseringen kommer mest sannolikt ske gradvis. I tidiga skeden spås självkörande lastbilar (AT:s) ha en konservativ körstil där körfältsbyten uThe truck sector is thought to be one of the first adopters of autonomous driving technology. Reduced fuel- and labour costs, increased flexibility in scheduling and increased hours of service, are all incentives for the freight companies to go autonomous. The automation of the truck fleet is likely to be gradual. At first, autonomous trucks (AT:s) are expected to have a conservative driving style
Wood decay fungi are often classified as either brown rot or white rot, depending on their mechanism of accessing nutrients in wood. This dichotomy assumes that white rot fungi break down lignin with various enzymes, while brown rot fungi leave it mostly unmodified and instead bypass it with diffusion of small molecules to reach the desired hemicellulose and cellulose. The effect of different sour
Abstract Host genes for resistance to pathogens and parasites have been a subject of long-term research efforts and continue to be a hot subject in biology. Many important theories have been hypothesized through the years, and they are now being complemented by new and more detailed ones leading to increased understanding of the complex dynamics between host life history strategies and the select
Denna uppsats syftar till att utreda vilken betydelse erkännandet har i brottmålsprocessen i Sverige. Uppsatsens fyra frågeställningar utgör ramen, och innefattar såväl en allmän del om bevisprövning som en djupdykning i erkännandets prövning och styrka som bevis. I uppsatsen används huvudsakligen rättsdogmatisk metod. Dock görs även en undersökning av sex omtalade tingsrättsdomar för att se hur pThis essay aims to study the importance of confessions in Swedish criminal law procedure. The essay consists of a general overview of the court’s evaluation of evidence as well as an examination of how the courts perceive confessions and the strength of a confession as evidence. Six renowned district court rulings have been analyzed to see how the law is applied. Since this area is largely unregul
