Filtyp
Objectives To study the association between lifestyle risk factors and chronic hypertension by history of hypertensive disorders of pregnancy (HDP: gestational hypertension and pre-eclampsia) and investigate the extent to which these risk factors modify the association between HDP and chronic hypertension. Design Prospective cohort study. Setting Nurses' Health Study II (1991-2013). Participants 5
Gestational diabetes mellitus(GDM) defines an unhealthy state of hyperglycaemia that develops in response to an otherwise normal physiological adaptive insulin resistance state during pregnancy. However, the exact plasma glucose levels differentiating the unhealthy GDM state from a normal pregnancy is unknown, and relies upon arbitrary cut off criteria based on associations with adverse health out
Background: Domestic violence during pregnancy is not only a severe public health issue that jeopardizes maternal and foetal health but also violates human rights. The aim was to explore the prevalence and incidence of domestic violence among pregnant women, in the southwestern region of Scania in Sweden, and their experience of a history of violence. In addition, to explore the association betwee
Reaction of Ru3(CO)12 with tris(2-thienyl)phosphine (PTh3) in CH2Cl2 at room temperature or in THF in the presence of a catalytic amount of Na[Ph2CO] furnishes the carbonyl substitution products Ru3(CO)11(PTh3) (1), Ru3(CO)10(PTh3)2 (2), and Ru3(CO)9(PTh3)3 (3). Heating 1 in toluene affords the cyclometalated cluster Ru3(CO)9{μ-Th2P(C4H2S)}(μ-H) (4) resulting from carbonyl loss and carbon-hydrogen
Background Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show pleiotropy; that is, they are also associated with other diseases or traits. Objectives This study sought to systematically test if genetic variants identified for non-CAD diseases/traits also associate with CAD and to undertake a comprehensive analysi
Background: The use of placebo comparisons for randomised trials assessing the efficacy of surgical interventions is increasingly being considered. However, a placebo control is a complex type of comparison group in the surgical setting and, although powerful, presents many challenges. Objectives: To provide a summary of knowledge on placebo controls in surgical trials and to summarise any recomme
A common migratory pattern in birds is that northerly breeding populations migrate to more southerly non-breeding sites compared to southerly breeding populations (leap-frog migration). Not only do populations experience differences in migration distances, but also different environmental conditions, which may vary spatiotemporally within their annual cycles, creating distinctive selective pressur
Background: Half the children with high-risk neuroblastoma die with widespread metastases. Molecular radiotherapy is an attractive systemic treatment for this relatively radiosensitive tumor. 131I-mIBG is the most widely used form in current use, but is not universally effective. Clinical trials of 177Lutetium DOTATATE have so far had disappointing results, possibly because the administered activi
Background: Ethiopia is one of the sub-Saharan countries hit hard by the HIV epidemic. Previous studies have shown that subtype C dominates the Ethiopian HIV-1 epidemic, but the evolutionary and temporal dynamics of HIV-1 in Ethiopia have not been closely scrutinized. Understanding the evolutionary and epidemiological pattern of HIV is vital to monitor the spread, evaluate and implement HIV preven
While the effects of particulate matter (PM) on morbidity and mortality are well-established, the specific properties of PM responsible for these effects are still not completely understood. However, identifying the toxic properties of particles is critical for developing cost-effective air quality standards and ultimately protecting public health. This dissertation investigates the potential heal
Purpose – The aim of this paper is to contribute with increased knowledge of the complex role of internal communication during a crisis like the COVID-19 pandemic. More specifically, the authors want to address the following research questions. How can the overall approach to internal crisis communication during the pandemic be interpreted, and what view of internal crisis communication does this
Popular Abstract in Swedish Tvärsektoriella nätverk mellan myndigheter, näringsliv och olika intressegrupper har tilldelats en allt större betydelse, då det varit en vanlig uppfattning att en hållbar utveckling bäst skapas genom ett gemensamt ansvar. Uppfattningarna om resultaten av dessa initiativ uppvisar dock spektakulära skillnader: från att framstå som oslagbara lösningar på de utmaningar soThe importance of cross-sectoral collaborative initiatives, that is partnerships of governments, civil society and the private sector, was elevated due to the belief that the issues of SD are a collective responsibility of all societal actors. The assessment of these initiatives is ranging dramatically; from giving them a status of an unbeatable solution for the SD challenges, to blaming them for
The cavitation phenomenon has today become a keystone for different areas of science and technology including various industrial processes and medicine. Recently increasing interest and much attention have been paid to study this phenomenon. The last two decades have witnessed the development of numerous devices for different important applications of considerable practical interest, and the rang
Popular Abstract in Swedish Antibiotikaresistens hos pneumokocker har utvecklats till ett problem i hela världen. Interkontinental spridning av ett fåtal resistenta kloner verkar stå för den snabba ökningen av förekomsten av pneumokocker med nedsatt känslighet för penicillin (PNSP). Förekomst av PNSP har reducerat behandlingsalternativen för såväl vanliga luftvägsinfektioner som invasiva infektionPneumococcal resistance to antibiotics has become a worldwide problem. The rapid increase in frequency seems to be caused by intercontinental spread of a few resistant clones. Resistance to antibiotics in pneumococci has reduced the therapeutic arsenal for common respiratory tract infections as well as for invasive infections. Problems of specific clinical concern are meningitis due to penicillin-
Background: SARS-CoV-2, the causal agent of COVID-19, enters human cells using the ACE2 (angiotensin-converting enzyme 2) protein as a receptor. ACE2 is thus key to the infection and treatment of the coronavirus. ACE2 is highly expressed in the heart and respiratory and gastrointestinal tracts, playing important regulatory roles in the cardiovascular and other biological systems. However, the gene
Synucleinopathies are neurodegenerative disorders characterized by intracellular protein aggregates, progressive neurodegeneration, and neuroinflammation. Alpha-synuclein (a-syn) is the principal component of intracellular aggregates and can be modified by several mutations and post-translational modifications (PTMs), which can alter the protein structure affecting its aggregation, toxicity, and a
Purpose or ObjectiveTo evaluate two commercial, CE labeled deep learning-based models for automatic organs at risk segmentation on planning CT images for prostate cancer radiotherapy. Model evaluation was focused on assessing both geometrical metrics and evaluating a potential time saving.Material and MethodsThe evaluated models consisted of RayStation 10B Deep Learning Segmentation (RaySearch Lab
BackgroundDiagnostic imaging is a dynamic medical field. In nuclear medicine, advancements introduce new procedures utilising innovative radiopharmaceuticals. These developments may influence supply requirements and exposure levels for the patient population. Surveying the frequency of procedures, types of pharmaceuticals, and administered activities provides valuable insights into utilisation tre
Apple is one of the most important pollinator-dependent fruit crops worldwide. To secure high-quality yields, it is crucial to know which, and to what extent, pollinating insects contribute to its pollination success as measured by fruit set, fruit weight and seed set. We perform a meta-analysis of field studies conducted across multiple orchards on insect-mediated pollination in apple cultivation
Birds periodically replace their flight feathers through moulting, a process needed to restore aerodynamic function that temporarily reduces the wing surface and flight performance. To mitigate these effects, birds adjust their wings, the angle of attack, and undergo mass loss to compensate for altered aerodynamics.Studying the aerodynamic impact of moult gaps in live birds is challenging, so we u
