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Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein structures, building phylogenetic trees etc. Although the automatic construction of a multiple sequence alignment for a set of remotely related sequences cause a very challenging and error-prone task, many downstream analyses still
The article provides an overview of ongoing research and key characteristics of Cognitive Semiotics, an emerging field dedicated to the transdiciplinary study of meaning, involving above all researchers from semiotics, linguistics, developmental and comparative psychology and philosophy. The combination of the following features distinguishes it from other synthetic approaches: (a) integration of
SGR012F: PhD Course Analyses in Qualitative Methods Course schedule, Spring Term 2022 Module 1) Date Time Location Topic/content Teachers Thursday Feb 17 9.15–12 13.15–16 Hus G 133 Hus G 133 Introduction Aims of qualitative methods Lecture: Generating data for analysis – access, sampling, material Kristina Göransson (KG) Malin Åkerström (MÅ) Tuesday Feb 22 9.15–12.00 13.15–16 Hus R 144 & Hus R 148
Objectives: Medial meniscal body extrusion ≥ 3 mm on MRI is often considered “pathologic.” The aims of this study were to (1) assess the adequacy of 3 mm as cut-off for “pathological” extrusion and (2) find an optimal cut-off for meniscal extrusion cross-sectionally associated with radiographic knee osteoarthritis, bone marrow lesions (BMLs), and cartilage damage. Methods: Nine hundred fifty-eight
Background: Faculty development roles are changing within organizations (Gibbs 2013). In previous research the expanding role in organizations as “Coming in from the margins” was described (Schroeder 2011). We studied how different levels of participation evolved within a research intense faculty with a complex organization and various educational programs.Summary of Work: The Centre was establish
Hypertension is considered the major modifiable risk factor for the development of cognitive impairment. Because increased blood pressure is often accompanied by an activation of the immune system, the concept of neuro-inflammation gained increasing attention in the field of hypertension-associated neurodegeneration. Particularly, hypertension-associated elevated circulating T-lymphocyte populatio
The development of business ecosystems in smart cities is currently hampered by the absence of established approaches for facilitating long-term value and sustainability. In our view, the underlying reason is the lack of collective action involving various organizations in the design process. Collective action for the good of the whole ecosystem does not take place in existing participatory practi
Although microfinance is often thought of as a tool to address poverty in developing countries, it is also being introduced in a number of countries in the developed world. The paper presents a qualitative study of the first year of the introduction of microfinance to address vulnerable groups in Sweden. Savings banks and nonprofit organisations collaborated in the introduction of microfinance as
Geophysical methods provide important information for mapping the subsurface. In semiarid areas, a detailed knowledge of the aquifers geometry can assist to a better management of groundwater. In the Valle Alto (Bolivia), which is a semiarid region, there is gap in the knowledge about the aquifer system geometry and hydrogeological processes. Local reports indicated problems in some wells such as
We explore the gravitational instability of clumpy and turbulent gas discs, taking into account the Larson-type scaling laws observed in giant molecular clouds (GMCs) and H i, as well as more general scaling relations. This degree of freedom is of special interest in view of the coming high-z interstellar medium surveys and is thus potentially important for understanding the dynamical effects of t
III-Nitride (III-N) materials are promising building blocks of optoelectronic devices such as light emitting diode and laser diode due to the unique material properties. Furthermore, direct and tunable band gaps of III-N materials enable them to cover the entire visible-UV region of electromagnetic spectrum for device applications. Even though the possibility of the fabrication of many devices bas
In order to improve curve safety, warning signs are used to alert drivers to unexpected changes in horizontal alignment and speed variations. While all countries have standards and guidelines for signs, markings and delineations to ensure a uniform system, they do not use them in the same way and choices and combinations may differ. SAFESTAR project promoted a method for establishing uniform curve
Carotenoid-based coloration in birds is widely considered an honest signal of individual condition, but the mechanisms responsible for condition dependency in such ornaments remain debated. Currently, the most common explanation for how carotenoid coloration serves as a reliable signal of condition is the resource trade-off hypothesis, which proposes that use of carotenoids for ornaments reduces t
Throughout time, communities have adapted to changes in their environment and, in doing so, have addressed risksthat threaten the things they value. The need to adapt is considered more urgent now than ever, notably given thecurrent focus on climate risk. Typically, adaptation is presented as a solution to reduce such risks. This is particularlythe case for Landlocked Developing Countries and Smal
The predictions of chiral perturbation theory for the weak non-leptonic decays of hyperons are examined beyond the leading order. For the S-wave amplitudes we find that the leading corrections to lowest order chiral perturbation theory preserve the vanishing of the Σ+ → nπ+ amplitude. However, the Lee-Sugawara relation gets a large correction indicating a breakdown of chiral perturbation theory fo
Objective: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is associated with life-threatening bleeding. This systematic review of postnatal management of FNAIT examined transfusion of human platelet antigen (HPA) selected or unselected platelets, and/or IVIg on platelet increments, hemorrhage and mortality. Study design: MEDLINE, EM
