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Validation of standardized creatinine and cystatin C GFR estimating equations in a large multicentre European cohort of children

Background: Most validations of paediatric glomerular filtration rate (GFR) estimating equations using standardized creatinine (CR) and cystatin C (CYS) assays have comprised relatively small cohorts, which makes accuracy across subgroups of GFR, age, body mass index (BMI) and gender uncertain. To overcome this, a large cohort of children referred for GFR determination has been established from se

Surveillance of COVID-19 vaccine effectiveness : A real-time case-control study in southern Sweden

The extensive register infrastructure available for coronavirus disease 2019 surveillance in Scania county, Sweden, makes it possible to classify individual cases with respect to hospitalisation and disease severity, stratify on time since last dose and demographic factors, account for prior infection and extract data for population controls automatically. In the present study, we developed a case

Potential air-quality improvements with future energy carriers in transportation

AimOur aim is to provide a-priori information on air-quality implications of potential future energy carriers in transportation relevant for sustainability, life cycle and health-impact assessments.MethodologyInformation on air- and climate-pollutant formation from energy carriers is collected in detailed laboratory assessments on heavy-duty combustion engines as well as on non-tailpipe emissions.

Investigating the causal relationships between excess adiposity and cardiometabolic health in men and women

AIMS/HYPOTHESIS: Excess adiposity is differentially associated with increased risk of cardiometabolic disease in men and women, according to observational studies. Causal inference studies largely assume a linear relationship between BMI and cardiometabolic outcomes, which may not be the case. In this study, we investigated the shapes of the causal relationships between BMI and cardiometabolic dis

Autoimmunity to selenoprotein P predicts breast cancer recurrence

BackgroundLow concentrations of serum selenium (Se) and its main transporter selenoprotein P (SELENOP) are associated with a poor prognosis following breast cancer diagnosis. Recently, natural autoantibodies (aAb) with antagonistic properties to SELENOP uptake have been identified in healthy subjects, and in patients with thyroid disease. Given the potential transport disrupting properties, we hyp

Absorption and lymphatic transport of exogenous and endogenous arachidonic and linoleic acid in the rat

[3H]Arachidonic (20:4) and [14C]linoleic acid (18:2) were fed to thoracic duct-cannulated rats in test meals of either tracers alone, cream, Intralipid, pure arachidonic acid, or pure linoleic acid. Less [3H]20:4 than [14C]18:2 was recovered in chyle during the first 5 h. After cream feeding, the proportion of radioactivity found in phospholipids was high and increased during the first 3 h. After [3H]Arachidonic (20:4) and [14C]linoleic acid (18:2) were fed to thoracic duct-cannulated rats in test meals of either tracers alone, cream, Intralipid, pure arachidonic acid, or pure linoleic acid. Less [3H]20:4 than [14C]18:2 was recovered in chyle during the first 5 h. After cream feeding, the proportion of radioactivity found in phospholipids was high and increased during the first 3 h. After

What makes children learn how to swim? – health, lifestyle and environmental factors associated with swimming ability among children in the city of Malmö, Sweden

Background: Swimming ability among children in the city of Malmö, Sweden is strongly affected by socioeconomic differences. We investigated to what extent mediating health and lifestyle factors, such as children’s eating, sleeping and physical activity habits, as well as the characteristics of the social and working environment at both school and home, could explain the socioeconomic gradient in s

Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations. Diabetes affects hundreds of millions of people worldwide, many of whom will develop life-threatening complications and die prematurely. Precision medicine can potentially address this enormous proble

Professorsinstallationen 15mars2013 ny

Professorsinstallation Lunds universitet | auLan | 15 mars 2013 kL 16.00 Denna broschyr finns på installandis institutioner och kan också beställas från kommunikationsavdelningen, tel 046-222 70 10, e-post info@rektor.lu.se. Broschyren finns även på www.lu.se/om-universitetet/akademiska-hogtider/professors- installationer Produktion Kommunikationsavdelningen, Lunds universitet Foto Kennet Ruona Tr

https://www.lu.se/sites/www.lu.se/files/professorsinstallationen_15mars2013_ny.pdf - 2026-06-03

Workshop NRCF 20250311 Final

Helping students learn uncertainty and significant figures Mätfel i gymnasiefysiken Workshop Elisabeth Nilsson, Lena Claesson & Lukasz Michalak Nationellt resurscentrum för fysik Nationellt Resurscentrum för Fysik, 2025-03-11 www.nrcf.lu.se Stående uppvärmning Bilda par – finn en “främling” Svara, var och en, på 3 frågor (2 min): “Varför har du valt att vara med här?” “Vad förväntar du att lära di

https://www.nrcf.lu.se/sites/nrcf.lu.se/files/2025-03/Workshop%20NRCF%2020250311%20final.pptx - 2026-06-03

Convergent input to the main output neurons of the decision making center of a bee brain

Centret för navigation i hjärnan hos ett bi I hjärnan hos ett litet bi som kallas Megalopta genalis finns en del som utgör centret för bland annat navigation. Detta navigationscenter benämns det centrala komplexet och ligger bakom de sofistikerade sätt som denna lilla organism förflyttar sig på i sin omvärld. Det har forskats på det centrala komplexet under flera år och nyligen kartlade några for

Analysing and Comparing the Intra-Halo Region in Milky Way-like Simulations

Universum är en underlig plats som har ställt många frågor, vissa som vi svarat på men många är kvar och ännu fler är okända. En av de som vi aktivt börjat besvara är frågan om mörk materia. Hur vet vi att det finns? Hur kan vi veta mer? Vad är det? Den första av dessa delfrågor har vi redan besvarat, vi vet att mörk materia finns för att det behövs någon osynlig massa för att, bland annat, rotatiDark matter has an important role in our Universe, especially in galaxy formation and evolution, but there are many theoretical models that attempt to describe it and to find out which one, if any, are correct we must test them. Testing a theoretical model of this nature at a galactic scale must and has been done using computational methods through simulations, but this has revealed more complicat

Personcentrad digital och interaktiv palliativ vård

Genom projektet har vi har strukturerat ett digitalt vårdförlopp som inte bara förbättrar tillgängligheten och flexibiliteten för patienter i palliativ vård, utan även ger närstående ett bättre stöd och underlättar kommunikationen med vården. Projektet syftar till att införa fler digitala vårdlösningar i den palliativa öppenvården genom 1177.se-plattformen, och därmed stärka vårdens strategiska må

Validation of a Digital Pathology–Based Multimodal Artificial Intelligence Biomarker in a Prospective, Real-World Prostate Cancer Cohort Treated with Prostatectomy

Purpose: A multimodal artificial intelligence (MMAI) biomarker was developed using clinical trial data from North American men with localized prostate cancer treated with definitive radiation, using biopsy digital pathology images and key clinical information (age, PSA, and T-stage) to generate prognostic scores. This study externally validates the biomarker in a prospective, real-world dataset of

Extending the dynamic range and endurance of ferroelectric tunnel junctions by conductance growth control

We use a closed-loop algorithm to accurately program hafnium zirconium oxide (HZO) ferroelectric tunnel junctions (FTJs) to arbitrary chosen target conductance values. The key enabler is suppression of conductance growth. We have identified two different mechanisms contributing to the total conductance of FTJs. By controlling both, we demonstrated an up to threefold increase of the usable conducta

National implementation of vaginal Natural Orifice Transluminal Endoscopic Surgery for benign hysterectomies : A historical cohort study of Swedish data 2021–2023

Introduction: Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a technique combining vaginal entrance to the abdomen with endoscopic overview. Previous studies have shown that vNOTES decreases operating time, hospitalization, postoperative complications, and pain. We aimed to present patient demographics, costs, and surgical outcomes following the implementation of vNOTES for be