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In spite of the similar structural and genomic organization of human immunodeficiency viruses type 1 and 2 (HIV-1 and HIV-2), striking differences exist between them in terms of replication dynamics and clinical manifestation of infection. Although the pathomechanism of HIV-1 infection is well characterized, relatively few data are available regarding HIV-2 viral replication and its interaction wi
The Western Gneiss Region (WGR) is a Precambrian basement domain in the Scandinavian Caledonides and one of the world's largest high- and ultrahigh-pressure terranes. The south–central WGR underwent regional eclogite facies metamorphism 415–400 Ma ago when Baltica subducted beneath Laurentia, during the Scandian orogeny. Eclogites in the WGR group into two traditional types: (1) Precambrian mafic
Esophagectomy is a complex and complication laden procedure. Despite centralization, variations in perioparative strategies reflect a paucity of evidence regarding optimal routines. The use of nasogastric (NG) tubes post esophagectomy is typically associated with significant discomfort for the patients. We hypothesize that immediate postoperative removal of the NG tube is non-inferior to current r
Research on personality traits predicting life outcomes has typically been investigated using the Big Five factors and only occasionally their facets. However, recent research suggests that the use of items (reflecting personality nuances) can account for more predictive variance. The aim of the present study was to examine the predictive validity for various life outcomes comparing the hierarchic
The Saccharomyces cerevisiae Elongator complex consisting of the six Elp1-Elp6 proteins has been proposed to participate in three distinct cellular processes: transcriptional elongation, polarized exocytosis, and formation of modified wobble uridines in tRNA. Therefore it was important to clarify whether Elongator has three distinct functions or whether it regulates one key process that leads to m
Introduction: The Interpersonal-Psychological Theory of Suicide proposes that capability for suicide is acquired through exposure to painful and provocative events (PPEs). Although there is robust evidence for a positive association between aggregate measures of PPEs and risk for suicidal behavior, little is known about the contributions of physical injuries. The present study investigated the rel
This work concerns reduction of the peak flow rate of a district heating grid,a key system property which is bounded by pipe dimensions and pumpingcapacity. The peak flow rate constrains the number of additional consumersthat can be connected, and may be a limiting factor in reducing supplytemperatures when transitioning to the 4th generation of district heating.We evaluate a full year of operatio
Purpose: Forehead flaps are commonly used in oculoplastic surgery to cover defects after tumor excision. Blood perfusion is vital for flap survival. The aim of this study was to monitor the perfusion in forehead flaps and investigate the impact of flap length and thickness. Methods: Nineteen forehead flaps in patients undergoing direct brow lift were studied. Perfusion was monitored using laser sp
Background: Congestion is associated with poor prognosis in cardiac amyloidosis (CA). The cardio-hepatic interaction and the prognostic impact of secondary liver affection by cardiac congestion in CA are poorly understood and require further characterisation. Methods: Participants of the amyloidosis cohort study AmyKoS at the Interdisciplinary Amyloidosis Centre of Northern Bavaria with proven tra
We tested the chondrogenic potential of demineralized allogeneic bone matrix (DABM) in the repair of osteochondral defects. In 42 adult rabbits, a 5-mm2 or 15-mm2 defect was created bilaterally in the intercondylar groove of distal femur. DABM was inserted directly in 37 defects, whereas in 35 it was inserted after previous placement in muscle for 4, 16, or 19 days. Another 12 defects were left em
Background: Insufficient physical activity is a growing public health concern and is closely linked to obesity in both adults and children. Swedish physical activity on prescription (PAP) is effective in increasing physical activity levels in adults, but knowledge about how PAP is used in paediatric healthcare is lacking. Therefore, this study aimed to explore experiences of working with PAP for c
BackgroundChildren and adolescents treated for a brain tumor suffer from more fatigue than survivors of other types of childhood cancer. As tumor location might be predictive of fatigue, our aim was to investigate the longitudinal development of fatigue in children with brain tumors and risk factors for fatigue separately for different tumor locations.MethodsFatigue was assessed 1235 times for 425
In this essay I argue that with too few alternative approaches, the strong feminist epistemological habit of attending to the political utility of art risks placing representations of subjective narratives whose emancipatory qualities might be unclear or doubtful out of scholarly reach. Feminist art historian Irit Rogoff discusses how feminist art historians are inclined to acknowledge visual repr
To stay competitive in today’s environment, characterized by changing customer requirements, digitalization, new technologies, etc., companies must deliver fast and continuous innovation. Manufacturing companies have therefore started to launch large-scale agile transformation initiatives. A specificity of manufacturing companies is their need for deeply specialized organizational units. Knowledge
This article analyses the claims of contemporary disabilityrights activists mobilising in a context where de facto second-class citizenship co-exists with legal and political declarationsabout the rights of disabled people. As an empirical case,it focuses on the blog ‘Full Participation.Now’, which wasinitiated by disability rights activists in Sweden. Drawing uponcitizenship research, the article
Weighted blankets are a non-pharmacological intervention for treating sleep and anxiety problems in children with attention-deficit/hyperactivity disorder. However, research on the efficacy of weighted blankets is sparse. The aim of this randomized controlled trial with a crossover design (4 + 4 weeks) was to evaluate the efficacy of weighted blankets on sleep among children with attention-deficit
We set up a mortality surveillance system around two of the largest gold mines in Tanzania between February 2019 and February 2020 to estimate the mortality impact of gold mines. Death circumstances were collected using a standardized verbal autopsy tool, and causes of death were assigned using the InSilicoVA algorithm. We compared cause-specific mortality fractions in mining communities with othe
