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The major seminal vesicle secreted proteins in human semen, semenogelin I and semenogelin II, interact non-covalently and via disulphide bridges to instantly form a coagulum upon ejaculation. The coagulum is liquefied after a few minutes due to the action of a prostatic serine protease, prostate-specific antigen (PSA). In contrast to rat semen, which forms an insoluble plug within minutes of expul
The role of inflammation in atherosclerosis and plaque vulnerability is well recognized. However, it is only during recent years it has become evident that this inflammation is modulated by immune responses against plaque antigens such as oxidized LDL. Interestingly, both protective and pathogenic immune responses exist and experimental data from animal studies suggest that modulation of these imm
A parallel procedure for an effective optimization of relative position and orientation between two or more fragments has been implemented in the MOLCAS program package. By design, the procedure does not perturb the electronic structure of a system under the study. The original composite system is divided into frozen fragments and internal coordinates linking those fragments are the only optimized
Abnormalities within a limited number of small and medium enterprises (SMEs) in Australia are reported. A set of interrelated industrial issues are brought out in order to advance the state of knowledge and avoid similar abnormalities / irregularities and to bring back some ideas for the mitigations. Impacts on new automated systems and on industrial as well as safety standards are expected in the
We analyze the propagation of electromagnetic waves in nonlinear, bianisotropic, nondispersive, homogeneous media using simple waves and six-vector formalism. The Maxwell equations are formulated as an eigenvalue problem, whose solutions are equivalent to the characteristic propagation directions. We solve the oblique incidence of plane waves in vacuum on a half space of nonlinear material, and pr
Purpose: To compare the volume rendering technique (VRT) with maximum intensity projection (MIP) for aortic diameter measurements in MR angiography (MRA) data sets. Material and Methods: Existing contrast-enhanced 3-dimensional MRA and digital subtraction angiography (DSA) data sets from 20 patients were analyzed. In each MRA data set, two aortic diameters were measured using MIP and VRT. Agreemen
We present a paleomagnefic study of 1785 to 1770 Ma composite and mafic intrusions in Smaland, Sweden. A positive inverse baked contact test suggests the primary nature of their magnetization. The palaeomagnetic pole (45.7 degrees N, 182.7 degrees E, A(95)=8.0 degrees) may be regarded as a key pole for Fennoscandia. Available paleomagnetic data suggest that Laurentia and Fennoscandia/Balfica drift
Background & aims: Tissue transglutaminase autoantibodies (tTGA) are used as diagnostic markers of celiac disease. Different methods have been developed for the detection of tTGA of which enzyme-linked immunosorbent assays (ELISA), radiobinding assays (RBA) and electrochemiluminescence (ECL) assays are the most commonly used. Here we aimed to evaluate a novel antibody detection by agglutinatio
It has been proposed that the relatively low duty cycle of the European Spallation Source (ESS) linac allows acceleration of additional mathbfH^- ion pulses interleaved with the baseline proton pulses, representing a unique opportunity to construct a neutrino super beam (ESSnuSB) facility of unparalleled luminosity. Coupled with a distant Cherenkov detector, it is believed that evidence of CP viol
BACKGROUND: Amyloid-β (Aβ) is a normal product of neuronal activity, including that of the aggregation-prone Aβ42 variant that is thought to cause Alzheimer's disease (AD). Much knowledge about AD comes from studies of transgenic rodents expressing mutated human amyloid-β protein precursor (AβPP) to increase Aβ production or the Aβ42/40 ratio. Yet, little is known about the normal expression of Aβ
Mycobacterial infections, including tuberculosis, are a major health problem globally. Prevention and treatments of tuberculosis are challenging due to the poor efficacy of the current vaccine and the emergence of drug-resistant strains. Therefore, it is critical to increase our basic understanding of mycobacterial virulence strategies as well as the host immune response during infection in the co
The role of multiple groups of primary biological aerosol particles (PBAPs) as ice nucleating particles (INPs), and of ice formation processes such as time-dependent freezing of various INPs, and various secondary ice production(SIP) mechanisms in overall ice concentration has been evaluated in a range of cloud systems by simulating them numerically with the state-of-the-art ‘Aerosol-Cloud’ (AC) m
Purpose The paper proposes a framework for the successful deployment of Industry 4.0 (I4.0) principles in the aerospace industry, based on identified success factors. The paper challenges the perception of I4.0 being aligned with de-skilling and personnel reduction and instead promotes a route to successful deployment centred on upskilling and retaining personnel for future role requirements. Desi
There is a lack of knowledge among food manufacturers about adopting the Internet of Things (IoT)-based water monitoring system and its ability to support water minimisation activities. It is therefore necessary to investigate the applicability of IoT-based real-time water monitoring systems in a real food manufacturing environment to pursue water-saving opportunities accordingly. This article aim
During the first year of NASA's Mars 2020 mission, Perseverance rover has investigated the dark crater floor unit of Jezero crater and four samples of this unit have been collected. The focus of this paper is to assess the potential of these samples to calibrate the crater-based Martian chronology. We first review the previous estimation of crater-based model age of this unit. Then, we investigate
Strategy is considered one of the most central concepts in public relationsresearch and practice. However, public relations strategizing, i.e., the doingof strategy, remains a black-box concept in public relations and wouldbenefit from additional approaches to theorizing strategy. This conceptualarticle draws upon strategy-as-practice, practice theory, and the existentialistnotion of human modes o
Weighted blankets are a non-pharmacological intervention for treating sleep and anxiety problems in children with attention-deficit/hyperactivity disorder. However, research on the efficacy of weighted blankets is sparse. The aim of this randomized controlled trial with a crossover design (4 + 4 weeks) was to evaluate the efficacy of weighted blankets on sleep among children with attention-deficit
