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A species-wide phylogeographical study of the root vole (Microtus oeconomus ) was performed using the whole 1140 base pair mitochondrial (mt) cytochrome b gene. We examined 83 specimens from 52 localities resulting in 65 unique haplotypes. Our results demonstrate that the root vole is divided into four main mtDNA phylogenetic lineages that seem to have largely allopatric distributions. Net diverge
Collagen induced arthritis (CIA) is a common mouse model for rheumatoid arthritis. Two sets of truncated peptides derived from type II collagen have been prepared and tested for binding to A(q), a MHC-II molecule associated with development of CIA. Binding to A(q) correlated well with predictions from a computer-based model. T-cell hybridomas, obtained in CIA, were also used to study the ability o
Many individuals with prediabetes, as presently defined, will progress to diabetes (T2D) despite the considerable benefit of lifestyle modification. Therefore, it is paramount to screen individuals at increased risk with a more sensitive method capable of identifying prediabetes at an even earlier time point in the lengthy trajectory to T2D. This petition reviews findings demonstrating that the 1-
Open testicular wedge biopsy has electively been performed prior to completion of maintenance therapy for acute lymphoblastic leukemia. 25 boys during 6 years were included in this prospective study. Three boys developed testicular enlargement while on maintenance therapy and biopsies confirmed testicular leukemia. The remaining 22 boys were biopsied at termination of maintenance therapy. Occult t
A sensitivity analysis on test outcomes from the microscale combustion calorimeter was performed using flexible polyurethane foam as the sample material. Three input factors were investigated: sample preparation, heating rate and pyrolysis chamber atmosphere. The experiments were setup according to the principles of design of experiments and a full factorial design was implemented. In total, 39 ex
During the recent years improved operation techniques and administrative procedures have been developed for early rehabilitation. At the same time preoperative lifestyle intervention (prehabilitation) has revealed a large potential for additional risk reduction. The aim was to assess the quality of life and to estimate the cost-effectiveness of standard care versus an integrated programme includin
Based on a modified force balance model, new correlations were proposed for the prediction of vapor bubble departure radius in saturated and subcooled pool boiling under atmospheric pressure. To predict the departure radius, the wall temperature and contact angle are two important input parameters. Instead of the static contact angle, the present correlations use the dynamic advancing contact angl
Purpose: To find a practical method for estimating the degree of sliding that occurs in screw-plate devices used in hip-fracture surgery. Greater understanding of the sliding mechanisms in different fracture types should improve surgical technique and reduce the failure rate. Methods and Results: In dynamic screw-plate devices, the lag screw slides inside the barrel of the plate. A recent innovati
Multiplex proteomic platforms provide excellent tools for investigating associations between multiple proteins and disease (e.g., diabetes) with possible prognostic, diagnostic, and therapeutic implications. In this study our aim was to explore novel pathophysiological pathways by examining 92 proteins and their association with incident diabetes in a population-based cohort (146 cases of diabetes
We reconsider the Generalized Kadanoff–Baym Ansatz (GKBA) approximation for non-equilibrium Green’s functions and extend it to self-consistently define an equilibrium correlated (within GKBA) state in closed systems. The advantage of the proposed prescription is to avoid the preparation of the initial equilibrium correlated state via adiabatic switching-on of the correlations. A simple model syste
Music in different forms is significant in young people's lives. In this presentation play is applied as a theoretical perspective to reach a deeper understanding of children’s musical learning and creativity. This presentation discusses findings from two empirical studies where children ages 6-8 years engage in musical activities: a doctoral a study (Nilsson, 2002) of nine 7-8-year-old Swedish ch
A search for doubly charged scalar bosons decaying into W boson pairs is presented. It uses a data sample from proton–proton collisions corresponding to an integrated luminosity of 36.1 fb- 1 collected by the ATLAS detector at the LHC at a centre-of-mass energy of 13 TeV in 2015 and 2016. This search is guided by a model that includes an extension of the Higgs sector through a scalar triplet, lead
Essentials Protein S and FV-Short are synergistic cofactors to Tissue Factor Pathway Inhibitor α (TFPIα). An assay for the TFPIα synergistic cofactor activity of protein S with FV-Short was developed. The assay was specific for the synergistic TFPIα-cofactor activity of free protein S. Protein S deficient individuals with known mutations were correctly distinguished from controls. Summary: Backgro
The transition to a Circular Economy (CE) requires enabling conditions that remove existing barriers in product life extension and material recovery operations. This contribution investigates barriers to material resource efficiency strategies in the maritime sector in Scandinavia and discusses the potential of policy interventions to enable increased reuse and remanufacturing of ship components.
The commissioning of the MAX IV synchrotron radiation facility in Lund marks the dawn of a new generation of storage-ring-based light sources. This new generation delivers one order of magnitude higher performance and allows realization of groundbreaking experiments on a variety of systems and materials at the atomic and molecular levels. This paper reviews the conceptual basis of the MAX IV desig
Limits are set on the pair production of scalar leptoquarks, where all possible decays of the leptoquark into a quark (t, b) and a lepton (τ, ν) of the third generation are considered. The limits are presented as a function of the leptoquark mass and the branching ratio into charged leptons for up-type (LQ3 u → tν/bτ) and down-type (LQ3 d → bν/tτ) leptoquarks. Many results are reinterpretations of
