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Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis

Background The extent to which adult height, a biomarker of the interplay of genetic endowment and early-life experiences, is related to risk of chronic diseases in adulthood is uncertain. Methods We calculated hazard ratios (HRs) for height, assessed in increments of 6.5 cm, using individual-participant data on 174 374 deaths or major non-fatal vascular outcomes recorded among 1 085 949 people in

Bra regler men dålig tillämpning – en enkätstudie om pressetik och publicitetsskador

Med en enkätstudie undersöks i detta projekt hur effektivt de berörda anser att de medieetiska systemen ger upprättelse. Här är det värt att nämna att vi då arbetet inleddes bad PO-kansliet om hjälp att distribuera vår enkät till alla dem som stod bakom framgångsrika anmälningar under 2015. På så sätt skulle enkäten kunna genomföras samtidigt som anonymiteten i PO-systemet kunde

Structured physiotherapy including a work place intervention for patients with neck and/or back pain in primary care: an economic evaluation

A cluster-randomized controlled trial, WorkUp, was conducted for working-aged patients at risk of sick leave or on short-term sick leave due to acute/subacute neck and/or back pain in Sweden. The purpose of WorkUp was to facilitate participants to stay at work or in case of sick leave, return-to-work. The aim of this study was to study whether the WorkUp trial was cost- effective. Patients in the A cluster-randomized controlled trial, WorkUp, was conducted for working-aged patients at risk of sick leave or on short-term sick leave due to acute/subacute neck and/or back pain in Sweden. The purpose of WorkUp was to facilitate participants to stay at work or in case of sick leave, return-to-work. The aim of this study was to study whether the WorkUp trial was cost-effective. Patients in the i

Non-invasive imaging methodologies for assessment of radiation damage to bone marrow and kidneys from peptide receptor radionuclide therapy. : -

Background/Aims: Peptide receptor radionuclide therapy (PRRT) is becoming clinical routine for management of neuroendocrine tumours. The number of PRRT cycles is correlated with treatment effect but theoretically limited by off-target radiation damage to kidneys and bone marrow. New imaging biomarkers for assessment of PRRT tissue damage would enable evaluation of novel renal and bone marrow prote

Övervakning av fåglarnas populationsutveckling : Årsrapport för 2017

I denna rapport redovisas populationstrender för 208 svenska fågelarter för olika långa tidsperioder. Fåglarna har räknats vinter, vår och sommar enligt strikt standardiserade metoder. Sommarrespektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan 1996) men täcker hela Sverige på ett representativt sätt. Nattaktiva fåglar harWe present the results of the Swedish Bird Survey, run by the Department of Biology, Lund University, as a part of the National Monitoring Programme of the Swedish Environmental Protection Agency. The results for 2017 include data from: 575 winter point counts in 2016/2017 (42nd winter), of which 284 were carried out during the Christmas/New Year count, 223 summer point count routes (43rd year) an

Regulation of rod phototransduction machinery by ciliary neurotrophic factor

Ciliary neurotrophic factor (CNTF) promotes photoreceptor survival but also suppresses electroretinogram (ERG) responses. This has caused concerns about whether CNTF is detrimental to the function of photoreceptors because it is considered to be a potential treatment for retinal degenerative disorders. Here we report that the suppression of ERG responses is attributable to negative regulation of t

Why European and United States drug regulators are not speaking with one voice on anti-influenza drugs: regulatory review methodologies and the importance of 'deep' product reviews

BackgroundRelenza represents the first neuraminidase inhibitor (NI), a class of drugs that also includes the drug Tamiflu. Although heralded as breakthrough treatments in influenza, NI efficacy has remained highly controversial. A key unsettled question is why the United States Food and Drug Administration (FDA) has approved more cautious efficacy statements in labelling than European regulators f

The use of the nest for parental roosting and thermal consequences of the nest for nestlings and parents

At temperate latitudes, altricial birds and their nestlings need to handle night temperatures well below thermoneutrality during the breeding season. Thus, energy costs of thermoregulation might constrain nestling growth, and low nocturnal temperatures might require resources that parents could otherwise have invested into nestlings during the day. To manipulate parental work rate, we performed brAt temperate latitudes, altricial birds and their nestlings need to handle night temperatures well below thermoneutrality during the breeding season. Thus, energy costs of thermoregulation might constrain nestling growth, and low nocturnal temperatures might require resources that parents could otherwise have invested into nestlings during the day. To manipulate parental work rate, we performed br

Video capsule colonoscopy in routine clinical practice

Background: Colon capsule endoscopy (CCE) offers direct mucosal visualisation without sedation or gas insufflation required in conventional colonoscopy (CC). However, evidence for the role of CCE as an adjunct or alternative to CC remains equivocal. In this observational cohort study, we report our experience of using CCE to investigate patients with suspected colon pathology at a tertiary referra

Complement activation negatively affects the platelet response to thrombopoietin receptor agonists in patients with immune thrombocytopenia: : a prospective cohort study

Increased platelet destruction is central in the pathogenesis of immune thrombocytopenia. However, impaired platelet production is also relevant and its significance underlies the rationale for treatment with thrombopoietin receptor agonists (TPO-RAs). Previous studies have associated enhanced complement activation with increased disease severity. Additionally, treatment refractoriness has been de

Millora 2.0: : Redovisning av resultat för 2018 –2022

[The project Millora 2.0: Results 2018–2022] Based on repeated yearly surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southernmost Sweden, analysed in combination with speciesspecific traits and ecological indicator values (EIVs), changes in the flora and vegetation over the last four years are reported. Many of the changes observed, such as significant increasesBased on repeated yearly surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southernmost Sweden, analysed in combination with speciesspecific traits and ecological indicator values (EIVs), changes in the flora and vegetation over the last four years are reported. Many of the changes observed, such as significant increases in lightdemanding, shortlived, pollinatorind

An inclusive and participatory approach to counter-radicalization? : Examining the role of Muslim associations in the Swedish policy process

Policies on preventing radicalization and recruitment to violent Islamist organizations have been widely criticized for reinforcing negative stereotypes of Muslims as a group. Sweden has stood out by international comparison by announcing an approach built on inclusion and participation, especially with regard to Muslim civil society. But what does it mean to make a policy process inclusive and pa

Exploring the challenges and facilitators that impact the experiences of being an older female worker in the European labour market: Findings from a rapid review of literature

Older women make a significant contribution to the labour market yet still experiencenegative workplace impacts. We undertook a rapid review of literature to assess theexperiences of older female workers in the European labour market with the aim toidentify current research gaps. We discuss how current data and future research couldbe utilized to improve the working lives of older women in Europe.

Fuel Prices and Environment-Friendly Innovations. Evidence from the Automobile Industry

This paper empirically examines the relationship between fuel prices and patenting activity in environment-friendly technologies in the auto industry across the OECD countries for the period 1994-2011. Overall, the results suggest that tax-inclusive fuel price affects innovative activity in environment-friendly technologies. More specifically, the analysis shows that the technologies aiming to red

Secondary Materials in Indian Manufacturing - Factors, barriers and the implications for secondary materials brokers

Consumer manufacturing brands are touting circular business models as the solution to current linear economy production systems that are overburdening the Earth’s ecological carrying capacity. Using secondary materials in manufacturing can reduce the waste generation and embedded environmental impacts associated with consuming manufactured goods. Companies such as Karo Sambhav seek to connect manu

Pyrotechnically Generated Aerosols ability to extinguish cable fires

This study aimed to evaluate the use of Pyrotechnically Generated Aerosols in electrical fires. To represent a common starting point for these fires, a cable fire ignited by a shortcut was chosen. In order to do this in a realistic way, a new method with heating the cables from the inside was used. This study examined whether the PGA has the ability to supress a cable fire inside an electrical cab

”Om ett träd bränns utan att någon räknar utsläppen…” En studie av relationen mellan vetenskap och beslutsfattande i EU:s ramverk för förnybar energi; REDII

This study examines the influence of scientific knowledge in rule-making processes aimed at reducing greenhouse gas emissions in the European Union. Specifically, the paper examines the case of regulation on forest biomass in the revised Renewable Energy Directive from 2018. Through the method of process-tracing, the paper seeks to explain the science-policy interface in the case. The so called “u

Pursuing a sustainable future. The capability approach as an alternative to transform neoliberal energy policies in the case of Turkey.

Since 1950s fossil fuels are the main source of anthropogenic emissions (Friedlingstein et al., 2019) and developing economies with their increasing demand of energy are contributing to global fossil fuel consumption increasingly. Turkey, similarly, has been experiencing an increase of energy demand and have been heavily relied on fossil fuels in consumption patterns. This study employs Fairclough

The effects of technological and digital development on the insurance industry - A multiple case study of the Swedish insurance industry

In recent years, the insurance industry has undergone a transformation where new technologies and digitalization has impacted the competitive structure of the industry and the value chain. The competitive structure in its turn may affect the incentives to innovate. This thesis attempts to examine how technological development and digitalization has affected different parts of the value chain in th

Self-Selection and Wage Consequences among Undocumented Central American Migrants in the United States - The Case of Nicaraguan, Guatemalan, and Salvadorian Migrants

After the U.S. intervention, civil wars, and growing violence during the late 20th century, migration from the Central American countries to the U.S. increased rapidly in the 1980s, especially illegal migration. The Nicaraguan Adjustment and Central American Relief Act (NACARA) granted Nicaraguans permanent residency, while the others could apply “only” for asylum or were not even mentioned. In th