Filtyp
Semiconductor nanowires are a promising candidate for next-generation solar cells. However, the optical response of nanowires is, due to diffraction effects, complicated to optimize. Here, we optimize through optical modeling the absorption in a dual-junction nanowire-array solar cell in terms of the Shockley-Quessier detailed balance efficiency limit. We identify efficiency maxima that originate
Erythroid cell commitment and differentiation proceed through activation of a lineage-restricted transcriptional network orchestrated by a group of well characterized genes. However, the minimal set of factors necessary for instructing red blood cell (RBC) development remains undefined. We employed a screen for transcription factors allowing direct lineage reprograming from fibroblasts to induced
The key steps in cellular signaling and regulatory pathways rely on reversible noncovalent protein-ligand binding, yet the equilibrium parameters for such events remain challenging to characterize and quantify in solution. Here, we demonstrate a microfluidic platform for the detection of protein-ligand interactions with an assay time on the second timescale and without the requirement for immobili
Vertical InAs/GaSb nanowire TFETs with diameters of 20 nm and 25 nm have been fabricated and characterized. The influence of diameter, gate-placement, and nanowire numbers have been studied. The best device shows a subthreshold swing of 68 mV/dec at VDS = 0.3 V and 26 μA/μm at VDS = 0.3 V and VGS = 0.5 V. It achieves a self-gain larger than 100 with high transconductance efficiency.
Background: In the course of our whole-genome sequencing efforts, we have developed a pipeline for analyzing germline genomes from Mendelian types of cancer pedigrees (familial cancer variant prioritization pipeline, FCVPP). Results: The variant calling step distinguishes two types of genomic variants: single nucleotide variants (SNVs) and indels, which undergo technical quality control. Mendelian
This study presents the first results from an ongoing initiative to develop a multi-millennial Baltic tree- ring width (TRW) chronology consisting of 12 floating records from subfossil Scots pines (Pinus sylvestris L.) extracted from three Lithuanian peat-mining areas. The floating series have been complemented with absolutely dated TRW chronologies which were obtained from living trees growing inThis study presents the first results from an ongoing initiative to develop a multi-millennial Baltic tree-ring width (TRW) chronology consisting of 12 floating records from subfossil Scots pines (Pinus sylvestris L.) extracted from three Lithuanian peat-mining areas. The floating series have been complemented with absolutely dated TRW chronologies which were obtained from living trees growing in
During the last decades, several research groups have used bisphosphonates for local application to counteract secondary bone resorption after bone grafting, to improve implant fixation or to control bone resorption caused by bone morphogenetic proteins (BMps). We focused on zoledronate (a bisphosphonate) due to its greater antiresorptive potential over other bisphosphonates. Recently, it has beco
Fishing access agreements with developing countries have been widely criticized, for example for contributing to overexploiting fish resources and threatening food security. However, there is littlequantitative evidence of their economic effects. We investigate how European Union (EU) fishing access agreements affect African partner countries’ fishery exports to OECD countries. We find that:• Fish
Objectives: Medial meniscal body extrusion ≥ 3 mm on MRI is often considered “pathologic.” The aims of this study were to (1) assess the adequacy of 3 mm as cut-off for “pathological” extrusion and (2) find an optimal cut-off for meniscal extrusion cross-sectionally associated with radiographic knee osteoarthritis, bone marrow lesions (BMLs), and cartilage damage. Methods: Nine hundred fifty-eight
Med hjälp av ett automatiserat mätsystem för partikelhalter i vatten har vattenkvaliteten vid Borensbergs vattenverk i Motala kommun undersökts under ett års tid med avseende på mikroskopiska partiklar i dricksvatten och råvatten. Antalet mikroskopiska partiklar registrerades som absoluta värden i realtid. I denna artikel diskuteras hur larmgränser skall definieras i praktiken för partikelhalter oDuring a one year long research project at Borensberg Waterworks, Motala, Sweden, water quality with respect to microscopic particle counts both in raw water and drinking water have been monitored by an online water quality monitoring system. Microscopic particle counts were documented with absolute values in real-time. In this paper, a discussion is introduced on how to analyze large data sets fr
Purpose To investigate multivoxel proton Magnetic Resonance Spectroscopy (1HMRS) biometrics for preoperative differentiation and prognosis of patients with brain metastases (MET), low-(LGG) and high grade glioma (HGG). Methods Thirty-five patients (15 HGG, 9 LGG and 11 MET) were included. Proton Magnetic Resonance Spectroscopy Imaging(1H-MRSI) data was assessed and neurochemical profiles for metab
Effective measurement of exposure to air pollution, not least NO2, for epidemiological studies along with the need to better management and control of air pollution in urban areas ask for precise interpolation and determination of the concentration of pollutants in nonmonitored spots. A variety of approaches have been developed and used. This paper aims to propose, develop, and test a spatial pred
Translation of novel discoveries to human disease is limited by the availability of human tissue-based models of disease. Precision-cut lung slices (PCLS) used as 3D lung tissue cultures (3D-LTCs) represent an elegant and biologically highly relevant 3D cell culture model, which highly resemble in situ tissue due to their complexity, biomechanics and molecular composition. Tissue slicing is widely
III-Nitride (III-N) materials are promising building blocks of optoelectronic devices such as light emitting diode and laser diode due to the unique material properties. Furthermore, direct and tunable band gaps of III-N materials enable them to cover the entire visible-UV region of electromagnetic spectrum for device applications. Even though the possibility of the fabrication of many devices bas
Lysozyme is known to form equilibrium clusters at pH ≈ 7.8 and at low ionic strength as a result of a mixed potential. While this cluster formation and the related dynamic and static structure factors have been extensively investigated, its consequences on the macroscopic dynamic behavior expressed by the zero shear viscosity η
An ecofriendly design of low-cost electrochemical sensor activated by low-grade photo-thermal energy can be a prime stepping-stone for the perspective developments of various renewable energy conversion and utilization schemes. In this study, an investigation of n-type indium arsenide (n-InAs)/aqueous solution of orange dye (OD)/Zinc (Zn) sensor was carried out at various molarities of 1, 2, and 3
From a theoretical point of view, result-based agri-environmental payments are clearly preferable to action-based payments. However, they suffer from two major practical disadvantages: costs of measuring the results and payment uncertainty for the participating farmers. In this paper, we propose an alternative design to overcome these two disadvantages by means of modelling (instead of measuring)
Simultaneous digital breast tomosynthesis (DBT) and mechanical imaging (MI) offer the potential to combine anatomic information from DBT with functional information from MI. This makes it possible to associate tissue stiffness with specific anatomic structures in the breast, a combination that can reduce false-positive findings by using the MI data to discriminate between ambiguous lesions in DBT.
