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This article introduces a novel testing system for investigating rock hydromechanical behavior with neutron and X-ray imaging techniques. The system comprises four subsystems: an axial compression system, a confining pressure system, a fluid flow system, and a triaxial cell. In order to enable imaging with both modalities to track fluid flow and deformation in situ and 3D, the cell was designed to
The Saccharomyces cerevisiae Elongator complex consisting of the six Elp1-Elp6 proteins has been proposed to participate in three distinct cellular processes: transcriptional elongation, polarized exocytosis, and formation of modified wobble uridines in tRNA. Therefore it was important to clarify whether Elongator has three distinct functions or whether it regulates one key process that leads to m
Live virtual constructive (LVC) flight simulations mix pilots flying actual aircraft, pilots flying in simulators, and computer-generated forces, in joint scenarios. Training resources invested in LVC scenarios must give a high return, and therefore pilots in both live aircraft and simulators need to experience training value for the extensive resources invested in both, an aspect not emphasized i
Varje år dör cirka 90 000 personer i Sverige, en klar majoritet av dessaberör på olika sätt människobehandlande professioner. Att stå infördöden eller vara anhörig till någon som har dött eller ska dö måste räknas till några av de situationer där en människa kan ses som mest utsatt. Vad finns det då för ambitioner om vilka kunskaper och kompetens de som möter dessa människor ska besitta? Att möta
Introduction The population-based Inter99 cohort has contributed extensively to our understanding of effects of a systematic screening and lifestyle intervention, as well as the multifactorial aetiology of type 2 diabetes (T2D) and cardiovascular disease. To understand causes, trajectories and patterns of early and overt cardiometabolic disease manifestations, we will perform a combined clinical d
The first evidence for the Higgs boson decay to a Z boson and a photon is presented, with a statistical significance of 3.4 standard deviations. The result is derived from a combined analysis of the searches performed by the ATLAS and CMS Collaborations with proton-proton collision datasets collected at the CERN Large Hadron Collider (LHC) from 2015 to 2018. These correspond to integrated luminosi
This is a protocol for a Cochrane Review (Overview). The objectives are as follows:. The aim of this study is to evaluate the benefits and harms of different interventions used in the management of TTN of the newborn.
We demonstrate a novel dispersion-scan (d-scan) scheme for single-shot temporal characterization of ultrashort laser pulses. The novelty of this method relies on the use of a highly dispersive crystal featuring antiparallel nonlinear domains with a random distribution and size. This crystal, capable of generating a transverse second-harmonic signal, acts simultaneously as the dispersive element an
The tunable electronic structure of graphene nanoribbons (GNRs) has attracted much attention due to the great potential in nanoscale electronic applications. Most methods to produce GNRs rely on the lithographic process, which suffers from the process-induced disorder in the graphene and scalability issues. Here, we demonstrate a novel approach to directly grow free-standing GNRs on step-bunched f
Metal particles are embedded in the polymer to form a polymer composite film as a seed layer on an insulating substrate to overcome the limitation that electrodeposited copper only occurring at the interface between the polymer and the metal electrode. In this work, we successfully developed a Cu-polythiophenes composite film (Cu-PT composite film) through a facile in-situ reduction method, obtain
Reviews of the effectiveness of interventions for school refusal (SR) rely upon well-conducted primary studies. Currently there are no guidelines for those conducting primary studies about the measurement of outcome following intervention for SR. Most people would agree that it is important to measure school attendance as an outcome but there has been little discussion about other constructs that
The development of biomaterials for wound healing applications requires providing a number of properties, such as antimicrobial action, facilitation of cell proliferation, biocompatibility and biodegradability. The aim of the present study was to investigate morphological and mechanical properties of zein-based microfibers, ultimately aimed at creating an environment suitable for wound healing. Th
Model programs such as the ‘environmental protection model city’ have become an inherent part of China’s urban environmental governance. The role of these incentive schemes for promoting best practice, however, has been neglected so far. In this study, we show that model city programs raise the bar in terms of environmental standards. What is more, model cities have a positive impact on regional e
BACKGROUND: Ovarian cancer risk in BRCA1 and BRCA2 mutation carriers has been shown to decrease with longer duration of oral contraceptive preparations (OCPs) use. While the effects of OCPs in the general population are well established (∼50% reduction), the estimated risk reduction in mutation carriers is much less precise due to potential bias and small sample sizes. In addition, only a few stud
Daylight availability for buildings has been an integral part of architecture since ancient times, yet for the vast majority of countries, criteria for daylight provision were not normative until the 20th century. This article examines the case of Sweden, where the term “daylight” first appeared in regulations in 1960, and assesses the daylight compliance of multi-dwelling buildings before and aft
The use of daratumumab in combination with established regimens for the treatment of newly diagnosed multiple myeloma has recently been authorized by the European Medicines Agency based on results from three separate phase III randomized, active controlled, open-label studies that have confirmed enhanced efficacy and tolerability in both transplant-ineligible (MMY3008 and MMY3007) and transplant-e
Decision-making is central to Software Product Management (SPM) and includes deciding on requirements priorities and the content of coming releases. Several algorithms for prioritization and release planning have been proposed, where humans with or without machine support enact a series of steps to produce a decision outcome. Instead of applying some specific algorithm to find an acceptable soluti
