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Background If carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some years. We assessed the long-term effects of successful CEA. Methods Between 1993 and 2003, 3120 asymptomatic patients from 126 centres in 30 countries were allocated equally, by blinded minimised rand
A severe water scarcity challenge is facing Iraq, which is predominantly due to the absence of water management policies, negatively impacting the water quantity and quality provision from the Tigris and Euphrates Rivers. Moreover, these practices have led to the intrusion of the Arabian Gulf salinity wedge into the Shatt Al-Arab River (SAR), which is the main water source for most water treatment
BACKGROUND: Rare locations of hernias, as well as primary ventral hernias under certain circumstances (cirrhosis, dialysis, rectus diastasis, subsequent pregnancy), might be technically challenging. The aim was to identify situations where the treatment strategy might deviate from routine management. METHODS: The guideline group consisted of surgeons from the European and Americas Hernia Societies
We initiate a proof complexity theoretic study of subsystems of cutting planes (CP) modelling proof search in conflict-driven pseudo-Boolean (PB) solvers. These algorithms combine restrictions such as that addition of constraints should always cancel a variable and/or that so-called saturation is used instead of division. It is known that on CNF inputs cutting planes with cancelling addition and s
Mutational signatures are patterns of mutations that arise during tumorigenesis. We present an enhanced, practical framework for mutational signature analyses. Applying these methods to 3,107 whole-genome-sequenced (WGS) primary cancers of 21 organs reveals known signatures and nine previously undescribed rearrangement signatures. We highlight interorgan variability of signatures and present a way
Background: Hypoxic-ischaemic encephalopathy (HIE) is a leading cause of mortality and long-term neurological sequelae, affecting thousands of children worldwide. Current therapies to treat HIE are limited to cooling. Stem cell-based therapies offer a potential therapeutic approach to repair or regenerate injured brain tissue. These preclinical findings have now culminated in ongoing human neonata
For all involved in astronomy, the importance of monitoring and determining astrophysical magnetic-field strengths is clear. It is also a well-known fact that the corona magnetic fields play an important part in the origin of solar flares and the variations of space weather. However, after many years of solar corona studies, there is still no direct and continuous way to measure and monitor the so
Objective: Previous studies of the consequences of unilateral hearing loss (UHL) on the functional-structural organization of the brain has included subjects with various degrees of UHL. We suggest that the consequences of a total loss of hearing in one ear might differ from those seen in subjects with residual hearing in the affected ear. Thus, the main aim of the present study was to compare the
Abstract: Sedan 1990-talet finns en till synes motstridig rörelse inom kulturområdet. Dels en tendens att kultursektorn, i dess nuvarande kulturpolitiskt mer traditionella avgränsning, uppfattas som alltmer marginaliserad. Dels att kultur i bredare bemärkelse efterfrågas i allt högre grad och inom allt fler områden. Rörelsen hänger samman med övergripande samhällsförändringar som globaliseringens Since the 1990s, there has been a seemingly contradictory movement in the field of culture. On the one hand, there is a tendency for the cultural sector, in its current cultural-political more traditional demarcation, to be perceived as increasingly marginalized. Secondly, that culture in a broader sense is in increasing demand and in more areas. The movement is connected with overarching societal
This is a protocol for a Cochrane Review (Overview). The objectives are as follows:. The aim of this study is to evaluate the benefits and harms of different interventions used in the management of TTN of the newborn.
We demonstrate a novel dispersion-scan (d-scan) scheme for single-shot temporal characterization of ultrashort laser pulses. The novelty of this method relies on the use of a highly dispersive crystal featuring antiparallel nonlinear domains with a random distribution and size. This crystal, capable of generating a transverse second-harmonic signal, acts simultaneously as the dispersive element an
The tunable electronic structure of graphene nanoribbons (GNRs) has attracted much attention due to the great potential in nanoscale electronic applications. Most methods to produce GNRs rely on the lithographic process, which suffers from the process-induced disorder in the graphene and scalability issues. Here, we demonstrate a novel approach to directly grow free-standing GNRs on step-bunched f
Metal particles are embedded in the polymer to form a polymer composite film as a seed layer on an insulating substrate to overcome the limitation that electrodeposited copper only occurring at the interface between the polymer and the metal electrode. In this work, we successfully developed a Cu-polythiophenes composite film (Cu-PT composite film) through a facile in-situ reduction method, obtain
Reviews of the effectiveness of interventions for school refusal (SR) rely upon well-conducted primary studies. Currently there are no guidelines for those conducting primary studies about the measurement of outcome following intervention for SR. Most people would agree that it is important to measure school attendance as an outcome but there has been little discussion about other constructs that
The development of biomaterials for wound healing applications requires providing a number of properties, such as antimicrobial action, facilitation of cell proliferation, biocompatibility and biodegradability. The aim of the present study was to investigate morphological and mechanical properties of zein-based microfibers, ultimately aimed at creating an environment suitable for wound healing. Th
OBJECTIVE: To evaluate a system for delivery of inhaled nitric oxide.DESIGN: Prospective, laboratory study.SETTING: Engineering laboratory.SUBJECTS: A standard ventilator (Servo Ventilator 300), supplemented with extra gas modules for nitric oxide delivery.INTERVENTIONS: Two ventilator-integrated gas modules, delivering < or = 10 parts per million (ppm) or < or = 100 ppm of nitric oxide, were used
